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Terminated Phase 2 Interventional Results available

Study of Sotatercept for the Treatment of Chemotherapy Induced Anemia in Patients With Metastatic Breast Cancer (MK-7962-012)

ClinicalTrials.gov ID: NCT00931606

Public ClinicalTrials.gov record NCT00931606. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 9:12 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Double-blind, Randomized, Placebo-Controlled Study of ACE-011 for the Treatment of Chemotherapy Induced Anemia in Patients With Metastatic Breast Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the percentage of participants in each sotatercept dose regimen who achieve a hematopoietic response during the treatment period including up to 2 months after the last dose of sotatercept treatment of chemotherapy-induced anemia (CIA) in participants with metastatic breast cancer. Hematopoietic response was defined as an increase in hemoglobin concentration of ≥ 1 g/dL relative to baseline for 28 consecutive days during the treatment period including up to 2 months after the last dose of sotatercept in the absence of red blood cell (RBC) transfusion or treatment with an erythropoiesis-stimulating agent (ESA).

Study identification

NCT ID
NCT00931606
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Enrollment
30 participants

Conditions and interventions

Interventions

Biological · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2009
Primary completion
Nov 17, 2010
Completion
Nov 17, 2010
Last update posted
Sep 12, 2023

2009 – 2010

United States locations

U.S. sites
28
U.S. states
20
U.S. cities
28
Facility City State ZIP Site status
Investigative Site Sedona Arizona
Investigative Site Hot Springs Arkansas
Investigative Site Beverly Hills California
Investigative Site Corona California
Investigative Site Fountain Valley California
Investigative Site Montebello California
Investigative Site Riverside California
Investigative Site Denver Colorado
Investigative Site Boynton Beach Florida
Investigative Site Hinsdale Illinois
Investigative Site Evansville Indiana
Investigative Site Wichita Kansas
Investigative Site Baltimore Maryland
Investigative Site Grand Rapids Michigan
Investigative Site Tupelo Mississippi
Investigative Site Kansas City Missouri
Investigative Site Nyack New York
Investigative Site Goldsboro North Carolina
Investigative Site High Point North Carolina
Investigative Site Winston-Salem North Carolina
Investigative Site Bismarck North Dakota
Investigative Site Middletown Ohio
Investigative Site Philadelphia Pennsylvania
Investigative Site Charleston South Carolina
Investigative Site Austin Texas
Investigative Site Dallas Texas
Investigative Site Tyler Texas
Investigative Site Lacey Washington

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00931606, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 12, 2023 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00931606 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →