ClinicalTrials.gov record
An Investigational Drug, PF-02341066, Is Being Studied In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene
ClinicalTrials.gov ID: NCT00932451
Public ClinicalTrials.gov record NCT00932451. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 2, Open-label Single Arm Study Of The Efficacy And Safety Of Pf-02341066 In Patients With Advanced Non-small Cell Lung Cancer (Nsclc) Harboring A Translocation Or Inversion Involving The Anaplastic Lymphoma Kinase (Alk) Gene Locus
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2 trial that will evaluate the safety and efficacy of PF-02341066 in patients with advanced non-small cell lung cancer with a specific gene profile involving the ALK gene. This trial will also allow patients from a Phase 3 trial who received standard of care chemotherapy (Study A8081007) to receive PF-02341066.
Study identification
- NCT ID
- NCT00932451
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 1,069 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2010 (Type not available)
- Primary completion
- Mar 2015 (Actual)
- Completion
- Dec 2015 (Actual)
- Last update posted
- Jan 13, 2017
2010 – 2015
United States locations
- U.S. sites
- 140
- U.S. states
- 27
- U.S. cities
- 74
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Comprehensive Blood and Cancer Center | Bakersfield | California | 93309 | — |
| Tower Cancer Research Foundation | Beverly Hills | California | 90211-1850 | — |
| Tower Hematology Oncology Medical Group | Beverly Hills | California | 90211-1850 | — |
| Moores UCSD Cancer Center | La Jolla | California | 92037 | — |
| UCSD Medical Center - La Jolla | La Jolla | California | 92093-0698 | — |
| Drug Shipping Address: Ronald Reagen University of California-Los Angeles | Los Angeles | California | 90095-6984 | — |
| Ronald Reagen University of California-Los Angeles Medical Center | Los Angeles | California | 90095 | — |
| UCLA Opthalmic Oncology Center | Los Angeles | California | 90095 | — |
| University of California-Los Angeles | Los Angeles | California | 90095 | — |
| University of California, Irvine-Medical Center | Orange | California | 92868-3298 | — |
| University of California, Irvine-Pharmacy | Orange | California | 92868-3298 | — |
| Stanford University-Cancer Center | Palo Alto | California | 94305 | — |
| UC Davis Cancer Center | Sacramento | California | 95817 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| UCSD Medical Center - Hillcrest | San Diego | California | 92103 | — |
| Santa Monica-UCLA Medical Center & Orthopaedic Hospital Clinical Laboratory | Santa Monica | California | 90404 | — |
| UCLA Hematology Oncology-Santa Monica | Santa Monica | California | 90404 | — |
| University of California-Los Angeles | Santa Monica | California | 90404 | — |
| Redwood Regional Medical Group Inc | Santa Rosa | California | 95403 | — |
| DRUG SHIPMENT: University of Colorado Cancer Center | Aurora | Colorado | 80045 | — |
| Rocky Mountain Lions Eye Institute | Aurora | Colorado | 80045 | — |
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Kaiser Permanente Colorado - Franklin | Denver | Colorado | 80205 | — |
| Kaiser Permanente Colorado - Rock Creek | Lafayette | Colorado | 80026 | — |
| Smilow Cancer Center at Yale New Haven, Oncology Pharmacy | New Haven | Connecticut | 06510 | — |
| Smilow Cancer Hospital at Yale New Haven | New Haven | Connecticut | 06510 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| Michael and Dianne Bienes Cancer Center, Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | — |
| Memorial Cancer Institute | Hollywood | Florida | 33021 | — |
| Cancer Center of South Florida Foundation, Inc. | Lake Worth | Florida | 33461 | — |
| Memorial Cancer Center (West) | Pembroke Pines | Florida | 33028 | — |
| H Lee Moffitt Cancer Center & Research Institute | Tampa | Florida | 33612 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| Emory Clinic | Atlanta | Georgia | 30322 | — |
| Emory University Clinic | Atlanta | Georgia | 30322 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Winship Cancer Institution | Atlanta | Georgia | 30322 | — |
| Georgia Cancer Specialists - Administrative Annex | Atlanta | Georgia | 30341 | — |
| MCG Health Cancer Center Pharmacy | Augusta | Georgia | 30912 | — |
| MCG Health System Pharmacy (Drug Shipment Only) | Augusta | Georgia | 30912 | — |
| Medical College of Georgia | Augusta | Georgia | 30912 | — |
| Georgia Cancer Specialists-Stemmer | Decatur | Georgia | 30033 | — |
| Georgia Cancer Specialists-Macon | Macon | Georgia | 31217 | — |
| Georgia Cancer Specialists-Kennestone | Marietta | Georgia | 30060 | — |
| Georgia Cancer Specialists-Northside | Sandy Springs | Georgia | 30342 | — |
| OnCare Hawaii, Inc. | Honolulu | Hawaii | 96813 | — |
| University of Hawaii - Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| Hawaii Medical Center East | Honolulu | Hawaii | 96817 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Chicago Medical Center (Attn: J Pi PharmD / A. Patel Pharm D) | Chicago | Illinois | 60637 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Ingalls Memorial Hospital (Drug Shipment Only) | Harvey | Illinois | 60426 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Monroe Medical Associates | Harvey | Illinois | 60426 | — |
| Monroe Medical Associates | Tinley Park | Illinois | 60477 | — |
| Indiana University Hospital Clarian Health | Indianapolis | Indiana | 46202 | — |
| Indiana University Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| Ship drug to: Investigational Drug Services | Indianapolis | Indiana | 46202 | — |
| Wishard Memorial Hospital | Indianapolis | Indiana | 46202 | — |
| Springmill Medical Clinic | Indianopolis | Indiana | 46290 | — |
| Monroe Medical Associates | Munster | Indiana | 46321 | — |
| The Community Hospital | Munster | Indiana | 46321 | — |
| Johns Hopkins Sidney Kimmel Comprehensive Cancer Center | Baltimore | Maryland | 21231 | — |
| The Harry and Jeanette Cancer Research Building | Baltimore | Maryland | 21231 | — |
| National Institutes of Health National Cancer Institute | Bethesda | Maryland | 20892 | — |
| Massachusette General Hospital | Boston | Massachusetts | 02114 | — |
| Massachussetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Isreal Deaconess Medical Center, Pharmacy FD B18 | Boston | Massachusetts | 02115 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Beth Isreal Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Dana Farber Cancer Institute/Pharmacy | Boston | Massachusetts | 02215 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Karmanos Cancer lnstitute at Farmington Hllls | Farmington Hills | Michigan | 48334 | — |
| Siteman Cancer Center | City of Saint Peters | Missouri | 63376 | — |
| Barnes-Jewish Hospital | St Louis | Missouri | 63110-1094 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-7680 | — |
| Dartmouth Hitchcock Medical Center/Mary Hitchcock Memorial Hospital | Lebanon | New Hampshire | 03756-0001 | — |
| University of New Mexico Eye Clinic | Albuquerque | New Mexico | 87106 | — |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87131 | — |
| NSLIJ Health System/Monter Cancer Center | Lake Success | New York | 11042 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| Long Island Jewish Medical Center | New Hyde Park | New York | 11040 | — |
| Memorial Sloan-Kettering Cancer Center: Rockefeller Outpatient Pavilion | New York | New York | 10022 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| IP Shipment: CUMC Research Pharmacy | New York | New York | 10032 | — |
| Memorial Sloan - Kettering Cancer Center | New York | New York | 10065 | — |
| Department of Medicine MSG at SUNY HSC at Syracuse, INC., d/b/a University Physicians | Oneida | New York | 13421 | — |
| Department of Medicine MSG at SUNY HSC at Syracuse, INC., d/b/a University Physicians | Oswego | New York | 13126 | — |
| SUNY Upstate Medical University, Regional Oncology Center | Syracuse | New York | 13210-2306 | — |
| Department of Medicine MSG at SUNY HSC at Syracuse, INC., d/b/a University Physicians | Syracuse | New York | 13210 | — |
| UNC Health Care | Chapel Hill | North Carolina | 27514 | — |
| UNC Hospitals, The University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599-7600 | — |
| Presbyterian Hospital Cancer Center | Charlotte | North Carolina | 28204 | — |
| Presbyterian Hospital Huntersville | Huntersville | North Carolina | 28078 | — |
| Southern Oncology Specialists | Huntersville | North Carolina | 28078 | — |
| Presbyterian Hospital Matthews | Matthews | North Carolina | 28105 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University Hospital East | Columbus | Ohio | 43205 | — |
| The Ohio State University Investigational Drug Services | Columbus | Ohio | 43210 | — |
| The Ohio State University James Cancer Hospital and Solove Research Institute | Columbus | Ohio | 43210 | — |
| James Care in Kenny | Columbus | Ohio | 43221 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Penn State Milton S. Hershey Medical Center, Penn State Hershey Cancer Institute | Hershey | Pennsylvania | 17033-0850 | — |
| Abramson Cancer Center of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15232 | — |
| Vincent Armenio, MD | East Providence | Rhode Island | 02914 | — |
| Pharma Resource | East Providence | Rhode Island | 02915 | — |
| Medical University of South Carolina - Hollings Cancer Center | Charleston | South Carolina | 29425 | — |
| Tennessee Oncology, PLLC | Dickson | Tennessee | 37055 | — |
| Tennessee Oncology, PLLC | Franklin | Tennessee | 37067 | — |
| Tennessee Oncology, PLLC | Gallatin | Tennessee | 37066 | — |
| Tennessee Oncology, PLLC | Hermitage | Tennessee | 37076 | — |
| Tennessee Oncology, PLLC | Lebanon | Tennessee | 37087 | — |
| Tennessee Oncology, PLLC | Murfreesboro | Tennessee | 37130 | — |
| Sarah Cannon Research Institute (Administration) | Nashville | Tennessee | 37203 | — |
| Sarah Cannon Research Institute (Pharmacy) | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37205 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37207 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37211 | — |
| Vanderbilt Cancer Clinic | Nashville | Tennessee | 37232-5536 | — |
| The Vanderbilt Chemo Clinic | Nashville | Tennessee | 37232-7610 | — |
| Tennessee Oncology, PLLC | Smyrna | Tennessee | 37167 | — |
| UT Southwestern Medical Center - Simmons Cancer Center Pharmacy | Dallas | Texas | 75390-9015 | — |
| University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75390 | — |
| University of Texas Southwestern University Hospital - Zale Lipshy | Dallas | Texas | 75390 | — |
| UT Southwestern University Hospital - William P. Clements, Jr | Dallas | Texas | 75390 | — |
| The University of Texas | Houston | Texas | 77030 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109 | — |
| Lisa Nakatsu, RPh (Drug Shipment Address) | Seattle | Washington | 98122 | — |
| Swedish Medical Center | Seattle | Washington | 98122 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 140 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00932451, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 13, 2017 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00932451 live on ClinicalTrials.gov.