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Completed Phase 2 Interventional Results available

Vismodegib in Treating Patients With Recurrent or Refractory Medulloblastoma

ClinicalTrials.gov ID: NCT00939484

Public ClinicalTrials.gov record NCT00939484. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 1:48 PM EST

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Official title

A Phase II Clinical Trial Evaluating the Efficacy and Safety of GDC-0449 in Adults With Recurrent or Refractory Medulloblastoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This phase II trial is studying how well vismodegib works in treating adult patients with recurrent or refractory medulloblastoma. Vismodegib may slow the growth of tumor cells and may be an effective treatment for medulloblastoma.

Study identification

NCT ID
NCT00939484
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
31 participants

Conditions and interventions

Interventions

Other · Drug

Eligibility (public fields only)

Age range
22 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2009 (Type not available)
Primary completion
May 2013 (Actual)
Completion
Aug 2015 (Actual)
Last update posted
Feb 25, 2016

2009 – 2015

United States locations

U.S. sites
13
U.S. states
9
U.S. cities
12
Facility City State ZIP Site status
Children's Hospital Los Angeles Los Angeles California 90027 —
Lucile Packard Children's Hospital Stanford University Palo Alto California 94304 —
UCSF Medical Center-Mount Zion San Francisco California 94115 —
Children's National Medical Center Washington D.C. District of Columbia 20010 —
Lurie Children's Hospital-Chicago Chicago Illinois 60611 —
Memorial Sloan-Kettering Cancer Center New York New York 10065 —
Duke University Medical Center Durham North Carolina 27710 —
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229 —
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104 —
Children's Hospital of Pittsburgh of UPMC Pittsburgh Pennsylvania 15224 —
Pediatric Brain Tumor Consortium Memphis Tennessee 38105 —
St. Jude Children's Research Hospital Memphis Tennessee 38105 —
Baylor College of Medicine Houston Texas 77030 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00939484, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 25, 2016 · Synced Nov 7, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00939484 live on ClinicalTrials.gov.

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