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Completed Phase 1Phase 2 Interventional

A Study of CDX-1401 in Patients With Malignancies Known to Express NY-ESO-1

ClinicalTrials.gov ID: NCT00948961

Public ClinicalTrials.gov record NCT00948961. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 30, 2026, 2:37 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I/II, Open-Label, Dose-Escalation Study of CDX-1401 in Patients With Malignancies Known to Express NY-ESO-1

Study identification

NCT ID
NCT00948961
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Celldex Therapeutics
Industry
Enrollment
70 participants

Conditions and interventions

Interventions

  • CDX-1401 Biological
  • CDX-1401 in combination with Resiquimod and/or Poly-ICLC Biological
  • Resiquimod Biological
  • poly-ICLC Biological

Biological

Eligibility (public fields only)

Age range
18 Years to 99 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2009
Primary completion
May 31, 2012
Completion
Jan 31, 2014
Last update posted
Jun 26, 2016

2009 – 2014

United States locations

U.S. sites
7
U.S. states
6
U.S. cities
6
Facility City State ZIP Site status
Yale Comprehensive Cancer Center New Haven Connecticut 06519-1717
Mount Sinai Comprehensive Cancer Center Miami Beach Florida 33140
Henry Ford Health System Detroit Michigan 48202
Memorial Sloan Kettering Cancer Center New York New York 10017
Weill Cornell Cancer Center New York New York 10065
Carolina BioOncology Institute, PLLC Huntersville North Carolina 28078
Providence Portland Cancer Center Portland Oregon 97213

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00948961, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 26, 2016 · Synced Apr 30, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00948961 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →