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Completed Phase 3 Interventional Results available

BIBW 2992 (Afatinib) Versus Chemotherapy as First Line Treatment in NSCLC With EGFR Mutation

ClinicalTrials.gov ID: NCT00949650

Public ClinicalTrials.gov record NCT00949650. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 4:01 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomised, Open-label, Phase III Study of BIBW 2992 Versus Chemotherapy as First-line Treatment for Patients With Stage IIIB or IV Adenocarcinoma of the Lung Harbouring an EGFR Activating Mutation

Study identification

NCT ID
NCT00949650
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Boehringer Ingelheim
Industry
Enrollment
345 participants

Conditions and interventions

Interventions

  • Pemetrexed Drug
  • BIBW 2992 Drug
  • Cisplatin Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 13, 2009
Primary completion
Feb 8, 2012
Completion
Mar 15, 2017
Last update posted
Apr 5, 2018

2009 – 2017

United States locations

U.S. sites
7
U.S. states
7
U.S. cities
7
Facility City State ZIP Site status
Highlands Oncology Group Fayetteville Arkansas 72703
Clinical Trials and Research Associates Inc Montebello California 90640
Innovative Medical Research of South Florida Miami Florida 33179
Crescent City Research Consortiom Marrero Louisiana 70072
Interlakes Foundation, Incorporated Rochester New York 14623
Lehigh Valley Hospital / Lehigh Valley Health Network Allentown Pennsylvania 18103
South Texas Institute of Cancer, Northwest Cancer Center Corpus Christi Texas 78410

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 126 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00949650, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 5, 2018 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00949650 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →