Pioglitazone for Oral Premalignant Lesions

ClinicalTrials.gov ID: NCT00951379

Public ClinicalTrials.gov record NCT00951379. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 21, 2026, 7:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase IIB Randomized, Placebo Controlled Trial of Pioglitazone for Oral Premalignant Lesions an Inter-consortium Collaborative Study

Study identification

NCT ID: NCT00951379
Recruitment status: Terminated
Study type: Interventional
Phase: Phase 2
Lead sponsor: National Cancer Institute (NCI); NIH
Enrollment: 52 participants

Conditions and interventions

Conditions

Oral Leukoplakia

Interventions

Pioglitazone hydrochloride Drug
placebo Other
laboratory biomarker analysis Other

Drug · Other

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jan 31, 2010
Primary completion: Feb 28, 2014
Completion: Feb 28, 2014
Last update posted: Apr 5, 2016

2010 – 2014

United States locations

U.S. sites: 11
U.S. states: 8
U.S. cities: 9

Facility	City	State	ZIP	Site status
University of Alabama at Birmingham	Birmingham	Alabama	35294	—
University of Iowa Hospitals and Clinics	Iowa City	Iowa	52242	—
Brigham and Women's Hospital	Boston	Massachusetts	02115	—
Masonic Cancer Center, University of Minnesota	Minneapolis	Minnesota	55455	—
Roswell Park Cancer Institute	Buffalo	New York	14263	—
Columbia University Medical Center	New York	New York	10032	—
Memorial Sloan-Kettering Cancer Center	New York	New York	10065	—
Weill Medical College of Cornell University	New York	New York	10065	—
Medical University of South Carolina	Charleston	South Carolina	29425	—
MD Anderson Cancer Center	Houston	Texas	77030	—
University of Wisconsin Hospital and Clinics	Madison	Wisconsin	53792	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT00951379, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 5, 2016 · Synced Jul 21, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00951379 live on ClinicalTrials.gov.

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