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Completed Phase 2 Interventional

Safety and Efficacy of TKI258 in FGFR1 Amplified and Non-amplified Metastatic HER2 Negative Breast Cancer

ClinicalTrials.gov ID: NCT00958971

Public ClinicalTrials.gov record NCT00958971. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 15, 2026, 6:33 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-center, Open Label Phase II Trial of TKI258 in FGFR1 Amplified and Non-amplified Metastatic or Advanced HER2 Negative Breast Cancer

Study identification

NCT ID
NCT00958971
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
43 participants

Conditions and interventions

Interventions

  • TKI258 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 30, 2009
Primary completion
Feb 28, 2011
Completion
Feb 28, 2011
Last update posted
Dec 18, 2020

2009 – 2011

United States locations

U.S. sites
18
U.S. states
9
U.S. cities
16
Facility City State ZIP Site status
Comprehensive Blood and Cancer Center Dept CBCC (3) Bakersfield California 93309
Tower Cancer Research Beverly Hills California 90211
UCLA/ University of California Los Angeles Div. of Hematology/Oncology Los Angeles California 90095
Cancer Care Associates Medical Group Dept. of CCA Redondo Beach California 90277
Central Coast Medical Oncology Corporation Santa Maria California 93454
Florida Cancer Specialists Dept.of FloridaCancerSpec. (2) Fort Myers Florida 33901
Kansas City Cancer Center KCCC (3) Overland Park Kansas 66210
Associates in Oncology/Hematology, P.C. Rockville Maryland 20850
Comprehensive Cancer Centers of Nevada Henderson Nevada 89052
UNC/ Lineberger Comprehensive Cancer Center Dept. of Linberger Cancer Ctr Chapel Hill North Carolina 27599-7295
Northwest Cancer Specialists Northwest Office (2) Portland Oregon 97210
Texas Oncology, P.A. Dept. of Texas Oncology Bedford Texas 76022
Texas Oncology, P.A. Austin Dallas Texas 75246
Texas Oncology, P.A. Presbyterian Hospital Dallas Texas 75246
Texas Oncology, P.A. Texas Oncology - Sammons Dallas Texas 75246
Tyler Cancer Center Dept.ofTylerCancerCtr. (2) Tyler Texas 75702
Fairfax Northern Virginia Hematology Oncology Fairfax NVH Fairfax Virginia 22031
Blue Ridge Research Center at Roanoke Neurological Center Blue Ridge Cancer Care Roanoke Virginia 24014

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00958971, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 18, 2020 · Synced May 15, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00958971 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →