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Completed Phase 2 Interventional Results available

GDC-0449 in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery

ClinicalTrials.gov ID: NCT00980343

Public ClinicalTrials.gov record NCT00980343. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 4:28 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Biomarker and Phase II Study of GDC-0449 in Patients With Recurrent Glioblastoma Multiforme

Study identification

NCT ID
NCT00980343
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
National Cancer Institute (NCI)
NIH
Enrollment
44 participants

Conditions and interventions

Interventions

  • vismodegib Drug
  • therapeutic conventional surgery Procedure
  • laboratory biomarker analysis Other
  • pharmacological study Other

Drug · Procedure · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2010
Primary completion
Apr 30, 2012
Completion
May 31, 2012
Last update posted
Aug 15, 2017

2010 – 2012

United States locations

U.S. sites
9
U.S. states
7
U.S. cities
8
Facility City State ZIP Site status
University of California at Los Angeles Los Angeles California 90095
University of California San Francisco San Francisco California 94115
Emory University/Winship Cancer Institute Atlanta Georgia 30322
Dana-Farber Cancer Institute Boston Massachusetts 02115
Henry Ford Hospital Detroit Michigan 48202
Wake Forest University Health Sciences Winston-Salem North Carolina 27157
University Hospitals Case Medical Center Cleveland Ohio 44106
Cleveland Clinic Foundation Cleveland Ohio 44195
University of Pennsylvania/Abramson Cancer Center Philadelphia Pennsylvania 19104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00980343, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 15, 2017 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00980343 live on ClinicalTrials.gov.

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