Comparison of NN1250 Versus Insulin Glargine in Subjects With Type 2 Diabetes
Public ClinicalTrials.gov record NCT00982644. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
NN1250-3579: A 52-week Randomised, Controlled, Open Label, Multicentre, Multinational Treat-to-target Trial Comparing the Efficacy and Safety of SIBA and Insulin Glargine, Both Injected Once Daily in Combination With Oral Anti-diabetic Drugs (OAD), in Subjects With Type 2 Diabetes Mellitus Currently Treated With OAD(s) and Qualifying for More Intensified Treatment / NN1250-3643: An Extension Trial to NN1250-3579 Comparing Safety and Efficacy of NN1250 Plus OAD(s) With Insulin Glargine Plus OAD(s) in Type 2 Diabetes (BEGIN™: Once Long)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This trial is conducted in Europe and the United States of America (USA). The aim of this trial is to compare NN1250 (insulin degludec (IDeg)) with insulin glargine (IGlar) in subjects with type 2 diabetes never treated with insulin followed by the extension trial investigating the long-term safety and tolerability in terms of comparing NN1250 with insulin glargine in subjects with type 2 diabetes. All oral anti-diabetic drug (OAD) treatment will be discontinued when trial participant enters the main trial (NN1250-3579) with the exception of metformin and dipeptidyl peptidase-IV (DPP-IV) inhibitor treatment (only in countries where DPP-IV inhibitor treatment is approved for combination treatment together with insulin, otherwise DPP-IV inhibitor treatment is also discontinued). Subjects who consent to participate in the extension trial will continue the treatment (NN1250 or insulin glargine + oral antidiabetic drugs (OADs)) to which they were randomly allocated in the 52 week main trial. The main period is registered internally at Novo Nordisk as NN1250-3579 while the extension period is registered as NN1250-3643.
Study identification
- NCT ID
- NCT00982644
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,030 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2009
- Primary completion
- Nov 30, 2010
- Completion
- Nov 30, 2010
- Last update posted
- Feb 8, 2017
2009 – 2010
United States locations
- U.S. sites
- 86
- U.S. states
- 28
- U.S. cities
- 83
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Novo Nordisk Investigational Site | Bay Minette | Alabama | 36507-4198 | — |
| Novo Nordisk Investigational Site | Birmingham | Alabama | 35209 | — |
| Novo Nordisk Investigational Site | Huntsville | Alabama | 35801 | — |
| Novo Nordisk Investigational Site | Goodyear | Arizona | 85395 | — |
| Novo Nordisk Investigational Site | Anaheim | California | 92801 | — |
| Novo Nordisk Investigational Site | Concord | California | 94520-1926 | — |
| Novo Nordisk Investigational Site | La Jolla | California | 92037 | — |
| Novo Nordisk Investigational Site | Lancaster | California | 93534 | — |
| Novo Nordisk Investigational Site | Long Beach | California | 90806 | — |
| Novo Nordisk Investigational Site | Los Angeles | California | 90057 | — |
| Novo Nordisk Investigational Site | Mission Hills | California | 91345 | — |
| Novo Nordisk Investigational Site | National City | California | 91950 | — |
| Novo Nordisk Investigational Site | North Hollywood | California | 91606 | — |
| Novo Nordisk Investigational Site | Northridge | California | 91325 | — |
| Novo Nordisk Investigational Site | Palm Springs | California | 92262 | — |
| Novo Nordisk Investigational Site | San Mateo | California | 94401 | — |
| Novo Nordisk Investigational Site | Santa Monica | California | 90404 | — |
| Novo Nordisk Investigational Site | Spring Valley | California | 91978 | — |
| Novo Nordisk Investigational Site | Tarzana | California | 91356-3551 | — |
| Novo Nordisk Investigational Site | Tustin | California | 92780 | — |
| Novo Nordisk Investigational Site | Norwalk | Connecticut | 06851 | — |
| Novo Nordisk Investigational Site | Boynton Beach | Florida | 33472 | — |
| Novo Nordisk Investigational Site | Jacksonville | Florida | 32208 | — |
| Novo Nordisk Investigational Site | Melbourne | Florida | 32901 | — |
| Novo Nordisk Investigational Site | Miami | Florida | 33156 | — |
| Novo Nordisk Investigational Site | Miami | Florida | 33169 | — |
| Novo Nordisk Investigational Site | New Port Richey | Florida | 34652 | — |
| Novo Nordisk Investigational Site | Orange Park | Florida | 32073 | — |
| Novo Nordisk Investigational Site | Orlando | Florida | 32806 | — |
| Novo Nordisk Investigational Site | Palm Harbor | Florida | 34684 | — |
| Novo Nordisk Investigational Site | West Palm Beach | Florida | 33401 | — |
| Novo Nordisk Investigational Site | Decatur | Georgia | 30033 | — |
| Novo Nordisk Investigational Site | Fort Valley | Georgia | 31030-5008 | — |
| Novo Nordisk Investigational Site | Idaho Falls | Idaho | 83404-7596 | — |
| Novo Nordisk Investigational Site | Chicago | Illinois | 60607 | — |
| Novo Nordisk Investigational Site | Evansville | Indiana | 47714 | — |
| Novo Nordisk Investigational Site | Indianapolis | Indiana | 46217 | — |
| Novo Nordisk Investigational Site | Lexington | Kentucky | 40503 | — |
| Novo Nordisk Investigational Site | Paducah | Kentucky | 42003 | — |
| Novo Nordisk Investigational Site | Metairie | Louisiana | 70002 | — |
| Novo Nordisk Investigational Site | Slidell | Louisiana | 70461-4231 | — |
| Novo Nordisk Investigational Site | Greenbelt | Maryland | 20770 | — |
| Novo Nordisk Investigational Site | North East | Maryland | 21901 | — |
| Novo Nordisk Investigational Site | Reisterstown | Maryland | 21136-2516 | — |
| Novo Nordisk Investigational Site | Rockville | Maryland | 20852 | — |
| Novo Nordisk Investigational Site | Brockton | Massachusetts | 02301 | — |
| Novo Nordisk Investigational Site | North Dartmouth | Massachusetts | 02747 | — |
| Novo Nordisk Investigational Site | St Louis | Missouri | 63104 | — |
| Novo Nordisk Investigational Site | St Louis | Missouri | 63141 | — |
| Novo Nordisk Investigational Site | Henderson | Nevada | 89052-2649 | — |
| Novo Nordisk Investigational Site | Las Vegas | Nevada | 89117 | — |
| Novo Nordisk Investigational Site | Toms River | New Jersey | 08755-8050 | — |
| Novo Nordisk Investigational Site | Northport | New York | 11768 | — |
| Novo Nordisk Investigational Site | Staten Island | New York | 10301 | — |
| Novo Nordisk Investigational Site | Asheboro | North Carolina | 27203 | — |
| Novo Nordisk Investigational Site | Charlotte | North Carolina | 28209 | — |
| Novo Nordisk Investigational Site | Cincinnati | Ohio | 45255 | — |
| Novo Nordisk Investigational Site | Dayton | Ohio | 45406 | — |
| Novo Nordisk Investigational Site | Toledo | Ohio | 43606-2920 | — |
| Novo Nordisk Investigational Site | Oklahoma City | Oklahoma | 73103 | — |
| Novo Nordisk Investigational Site | Kingston | Pennsylvania | 18704 | — |
| Novo Nordisk Investigational Site | Langhorne | Pennsylvania | 19047 | — |
| Novo Nordisk Investigational Site | Melrose Park | Pennsylvania | 19027 | — |
| Novo Nordisk Investigational Site | Pittsburgh | Pennsylvania | 15241 | — |
| Novo Nordisk Investigational Site | West Reading | Pennsylvania | 19611 | — |
| Novo Nordisk Investigational Site | East Providence | Rhode Island | 02914 | — |
| Novo Nordisk Investigational Site | Columbia | South Carolina | 29203 | — |
| Novo Nordisk Investigational Site | Greer | South Carolina | 29651 | — |
| Novo Nordisk Investigational Site | Newberry | South Carolina | 29108-2249 | — |
| Novo Nordisk Investigational Site | Chattanooga | Tennessee | 37411 | — |
| Novo Nordisk Investigational Site | Harriman | Tennessee | 37748-8653 | — |
| Novo Nordisk Investigational Site | Humboldt | Tennessee | 38343 | — |
| Novo Nordisk Investigational Site | Nashville | Tennessee | 37203 | — |
| Novo Nordisk Investigational Site | Arlington | Texas | 76014 | — |
| Novo Nordisk Investigational Site | Corpus Christi | Texas | 78404 | — |
| Novo Nordisk Investigational Site | Dallas | Texas | 75230 | — |
| Novo Nordisk Investigational Site | Dallas | Texas | 75246 | — |
| Novo Nordisk Investigational Site | El Paso | Texas | 79912 | — |
| Novo Nordisk Investigational Site | Hurst | Texas | 76054 | — |
| Novo Nordisk Investigational Site | Irving | Texas | 75061-2210 | — |
| Novo Nordisk Investigational Site | Lubbock | Texas | 79423 | — |
| Novo Nordisk Investigational Site | San Antonio | Texas | 78215 | — |
| Novo Nordisk Investigational Site | Sugar Land | Texas | 77479 | — |
| Novo Nordisk Investigational Site | Richmond | Virginia | 23233 | — |
| Novo Nordisk Investigational Site | Spokane | Washington | 99218 | — |
| Novo Nordisk Investigational Site | Milwaukee | Wisconsin | 53209 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 101 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00982644, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 8, 2017 · Synced Sep 24, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00982644 live on ClinicalTrials.gov.