The RE-ENERGIZE Study: RandomizEd Trial of ENtERal Glutamine to minimIZE Thermal Injury
Public ClinicalTrials.gov record NCT00985205. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Effects of Enteral Glutamine Supplementation on Mortality and Infectious Morbidity in Severely Burned Patients: a Multi-center Pilot Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to test the following hypotheses: 1. Enteral glutamine administration decreases in-hospital mortality in adult patients with severe thermal burn injuries. 2. Enteral glutamine administration decreases hospital-acquired blood stream infections from Gram negative organisms and length of stay in ICU and hospital for adult patients with severe thermal burn injuries. 3. Enteral glutamine administration will improve the physical function of surviving burn injured patients and reduce their cost of care. The objectives of this trial are to determine the overall treatment effect and safety of glutamine in burn patients. Specifically, the investigators want to assess the following outcomes in a sample of 1200 patients in 80 sites: 1. In patients with severe, life-threatening burn injury, what is the effect of enteral glutamine on time to discharge alive from hospital 2. In patients with severe, life-threatening burn injury, what is the effect of enteral glutamine on 6 month mortality, hospital-acquired blood stream infections from Gram negative organisms, hospital mortality, duration of stay in ICU and hospital, health-related quality of life, and health care resources?
Study identification
- NCT ID
- NCT00985205
- Recruitment status
- Not listed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,201 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2010 (Actual)
- Primary completion
- Dec 2021 (Estimated)
- Completion
- Dec 2021 (Estimated)
- Last update posted
- Dec 30, 2021
2010 – 2021
United States locations
- U.S. sites
- 27
- U.S. states
- 19
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of South Alabama Medical Center | Mobile | Alabama | 36609 | — |
| Arizona Burn Center at Maricopa Medical Center | Phoenix | Arizona | 85008 | — |
| Southern California Regional Burn Ctr at LAC & USC Med. Ctr. | Los Angeles | California | 90089-9235 | — |
| Shriners Hospitals for Children Northern California | Sacramento | California | 95817 | — |
| Department of Anesthesiology, University of Colorado | Aurora | Colorado | 80045 | — |
| North Colorado Medical Center - Banner Health | Greeley | Colorado | 80631 | — |
| Connecticut Burn Center | Bridgeport | Connecticut | 06610 | — |
| The Burn Center at Washington Hospital Center | Washington D.C. | District of Columbia | 20782 | — |
| Shands Burn Center at the University of Florida | Gainesville | Florida | 32610 | — |
| University of South Florida/Tampa Gen. Hosp. Reg. Burn Center, FL | Tampa | Florida | 33606 | — |
| Joseph M Still Burn Center | Augusta | Georgia | 30909 | — |
| Department of Surgery University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | — |
| Mercy Hospital St. Louis | St Louis | Missouri | 63141 | — |
| CHI St.Elizabeth Regional Burn Center | Lincoln | Nebraska | 68150 | — |
| The Nebraska Medical Center | Omaha | Nebraska | 68198-7835 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Akron's Children's Hospital, Paul & Carol David Foundation | Akron | Ohio | 44308-1062 | — |
| The Ohio State University Wexnar Medical Center | Columbus | Ohio | 43210 | — |
| Legacy Emmanuel Hospital & Health Center | Portland | Oregon | 97232 | — |
| The Western Pennsylvania Hospital Burn Center | Pittsburgh | Pennsylvania | 15224 | — |
| Firefighters' Regional Burn Center TN, University of Tennesse Health & Sciences Center | Memphis | Tennessee | 38102 | — |
| University of Texas Southwestern | Dallas | Texas | 8563 | — |
| JBSA Fort Sam Houston | Fort Sam Houston | Texas | 78234-7767 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555 | — |
| Memorial Hermann/UTHSC | Houston | Texas | 77030 | — |
| Harbourview Medical Center | Seattle | Washington | 98195-9796 | — |
| Columbia-St. Mary's, Milwaukee, Wi | Milwaukee | Wisconsin | 53202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00985205, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 30, 2021 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00985205 live on ClinicalTrials.gov.