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ClinicalTrials.gov record
Terminated Phase 3 Interventional

Study of the Safety and Efficacy of Apadenoson for Detection of Myocardial Perfusion Defects Using SPECT MPI

ClinicalTrials.gov ID: NCT00990327

Public ClinicalTrials.gov record NCT00990327. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 4:42 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

The ASPECT Trial: A Phase III, Randomized, Double-Blind Crossover Trial of Apadenoson for the Detection of Myocardial Perfusion Defects Using Single-Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to see whether apadenoson is as effective as adenosine when used as a pharmacological stress agent in myocardial SPECT-Imaging to detect defects in the supply of blood to the heart muscle (myocardial perfusion defects). The study will also look at whether apadenoson is better tolerated than adenosine when used in SPECT-MPI.

Study identification

NCT ID
NCT00990327
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Forest Laboratories
Industry
Enrollment
863 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2009
Primary completion
Mar 31, 2012
Completion
Mar 31, 2012
Last update posted
Apr 30, 2012

2009 – 2012

United States locations

U.S. sites
103
U.S. states
37
U.S. cities
90
Facility City State ZIP Site status
Forest Investigative Site 152 Birmingham Alabama 35294
Forest Investigative Site 250 Mobile Alabama 36608
Forest Investigative Site 223 Phoenix Arizona 85006
Forest Investigative Site 191 Phoenix Arizona 85020
Forest Investigative Site 230 Jonesboro Arkansas 72401
Forest Investigative Site 153 Little Rock Arkansas 72204
Forest Investigative Site 108 La Mesa California 91942
Forest Investigative Site 111 Mission Viejo California 92691
Forest Investigative Site 234 Murrieta California 92562
Forest Investigative Site 146 Roseville California 95661
Forest Investigative Site 225 Sacramento California 95816
Forest Investigative Site 122 Sacramento California 95825
Forest Investigative Site 105 Santa Rosa California 95405
Forest Investigative Site 196 Walnut Creek California 94598
Forest Investigative Site 132 Hartford Connecticut 06102
Forest Investigative Site 102 Newark Delaware 19713
Forest Investigative Site 205 Daytona Beach Florida 32114
Forest Investigative Site 233 Edgewater Florida 32141
Forest Investigative Site 164 Gainesville Florida 32605
Forest Investigative Site 120 Jacksonville Florida 32207
Forest Investigative Site 198 Jacksonville Florida 32209
Forest Investigative Site 118 Jacksonville Florida 32216
Forest Investigative Site 124 Jacksonville Florida 32216
Forest Investigative Site 125 Jacksonville Florida 32258
Forest Investigative Site 126 Jacksonville Beach Florida 32250
Forest Investigative Site 180 Melbourne Florida 32901
Forest Investigative Site 183 Miami Florida 33136
Forest Investigative Site 106 Miami Florida 33173
Forest Investigative Site 201 Naples Florida 34119
Forest Investigative Site 240 Tampa Florida 33609
Forest Investigative Site 238 Wellington Florida 33449
Forest Investigative Site 155 Augusta Georgia 30912
Forest Investigative Site 199 Cumming Georgia 30041
Forest Investigative Site 204 Tucker Georgia 30084
Forest Investigative Site 116 Honolulu Hawaii 96813
Forest Investigative Site 137 Boise Idaho 83712
Forest Investigative Site 138 Boise Idaho 83712
Forest Investigative Site 227 Chicago Illinois 60612
Forest Investigative Site 228 Joliet Illinois 60435
Forest Investigative Site 173 Winfield Illinois 60190
Forest Investigative Site 113 Indianapolis Indiana 46260
Forest Investigative Site 168 Valparaiso Indiana 46383
Forest Investigative Site 171 West Des Moines Iowa 50266
Forest Investigative Site 133 Overland Park Kansas 66209
Forest Investigative Site 248 Crestview Hills Kentucky 41017
Forest Investigative Site 241 Owensboro Kentucky 42303
Forest Investigative Site 202 Alexandria Louisiana 71301
Forest Investigative Site 257 Covington Louisiana 70433
Forest Investigative Site 114 Auburn Maine 04210
Forest Investigative Site 107 Scarborough Maine 04074
Forest Investigative Site 109 South Portland Maine 04106
Forest Investigative Site 193 Baltimore Maryland 21208
Forest investigative Site 197 Westminster Maryland 21157
Forest Investigative Site 143 Detroit Michigan 48202
Forest Investigative Site 207 Petoskey Michigan 49770
Forest Investigative Site 177 Saint Louis Park Minnesota 55416
Forest Investigative Site 131 Tupelo Mississippi 38801
Forest Investigative Site 176 Kansas City Missouri 64132
Forest Investigative Site 159 St Louis Missouri 63110
Forest Investigative Site 188 Missoula Montana 59802
Forest Investigative Site 115 Albany New York 12205
Forest Investigative Site 212 Buffalo New York 14215
Forest Investigative Site 165 Kingston New York 12401
Forest Investigative Site 224 Manhasset New York 11030
Forest Investigative Site 139 Massapequa New York 11758
Forest Investigative Site 208 Raleigh North Carolina 27610
Forest Investigative Site 249 Sanford North Carolina 27330
Forest Investigative Site 214 Fargo North Dakota 58122
Forest Investigative Site 235 Akron Ohio 44304
Forest Investigative Site163 Columbus Ohio 43210
Forest Investigative Site 161 Columbus Ohio 43214
Forest Investigative Site 156 Lorain Ohio 44053
Forest Investigative Site 185 Sandusky Ohio 44870
Forest Investigative Site 101 Westlake Ohio 44145
Forest Investigative Site 182 Oklahoma City Oklahoma 73109
Forest Investigative Site 190 Bend Oregon 97701
Forest Investigative Site 217 Portland Oregon 97239
Forest Investigative Site 213 Camp Hill Pennsylvania 17011
Forest Investigative Site 154 Philadelphia Pennsylvania 19102
Forest Investigative Site 134 Philadelphia Pennsylvania 19140
Forest Investigative Site 218 Philadelphia Pennsylvania 19141
Forest Investigative Site 160 Pittsburgh Pennsylvania 15213
Forest Investigative Site 187 Sellersville Pennsylvania 18960
Forest Investigative Site 117 Wyomissing Pennsylvania 19610
Forest Investigative Site 149 Charleston South Carolina 29425
Forest Investigative Site 172 Simpsonville South Carolina 29681
Forest Investigative Site 229 Spartanburg South Carolina 29302
Forest Investigative Site 167 Johnson City Tennessee 37604
Forest Investigative Site 192 Johnson City Tennessee 37604
Forest Investigative Site 128 Amarillo Texas 79106
Forest Investigative Site 252 Grapevine Texas 76051
Forest Investigative Site 200 McKinney Texas 75069
Forest Investigative Site 181 Plano Texas 75024
Forest Investigative Site 253 San Antonio Texas 78215
Forest Investigative Site 186 Sugar Land Texas 77479
Forest Investigative Site 231 Tomball Texas 77375
Forest Investigative Site 232 Tomball Texas 77375
Forest Investigative Site 236 Provo Utah 84604
Forest Investigative Site 210 Charlottesville Virginia 22908
Forest Investigative Site 110 Roanoke Virginia 24014
Forest Investigative Site 151 Seattle Washington 98195
Forest Investigative Site 142 Spokane Washington 99204
Forest Investigative Site 144 Madison Wisconsin 53715

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00990327, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 30, 2012 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00990327 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →