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Completed Phase 1 Interventional Results available

Safety And Tolerability Study Of RN6G In Subjects With Advanced Dry, Age-Related Macular Degeneration Including Geographic Atrophy

ClinicalTrials.gov ID: NCT01003691

Public ClinicalTrials.gov record NCT01003691. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 9:14 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 1, DOUBLE-MASKED, PLACEBO-CONTROLLED STUDY EVALUATING THE SAFETY, TOLERABILITY, IMMUNOGENICITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF MULTIPLE ESCALATING DOSAGES OF RN6G (PF-04382923) IN SUBJECTS WITH ADVANCED DRY, AGE-RELATED MACULAR DEGENERATION (AMD) INCLUDING GEOGRAPHIC ATROPHY

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine the safety and tolerability of multiple doses of RN6G in subjects with advanced dry, age-related macular degeneration including geographic atrophy.

Study identification

NCT ID
NCT01003691
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Pfizer
Industry
Enrollment
24 participants

Conditions and interventions

Eligibility (public fields only)

Age range
60 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 4, 2010
Primary completion
Mar 4, 2013
Completion
Apr 18, 2013
Last update posted
May 11, 2022

2010 – 2013

United States locations

U.S. sites
24
U.S. states
6
U.S. cities
10
Facility City State ZIP Site status
Retinal Diagnostic Center Campbell California 95008
American Institute of Research (Administrative Only) Los Gatos California 95032
Neurology Center Rai Kumar San Jose California 95116
Harmeet Sachdev, MD, FAAN San Jose California 95124
Santa Clara Drug San Jose California 95128
Retina Associates of Florida, PA Tampa Florida 33609
Hoye's Pharmacy Tampa Florida 33611
Ranjit K. Sethi, MD, PC Augusta Georgia 30901
Clinical Specialists, LLC Augusta Georgia 30907
Southeast Retina Center, PC Augusta Georgia 30909
University of Rochester Medical Center Rochester New York 14642
University of Rochester Rochester New York 14642
Hawthorne Pharmacy West Columbia South Carolina 29169
Jay Markowitz and Associates West Columbia South Carolina 29169
Palmetto Retina Center, LLC West Columbia South Carolina 29169
South Carolina Neurological West Columbia South Carolina 29169
National Central Pharmacy Abilene Texas 79605
Abilene Surgery Center Abilene Texas 79606
Heart and Vascular Institute Abilene Texas 79606
Retina Research Institute of Texas Abilene Texas 79606
Brian B. Berger, MD, PA Austin Texas 78705
Retina Research Center, PLLC Austin Texas 78705
Sleep Medicine Consultants Austin Texas 78731
Specialty Compounding Cedar Park Texas 78613

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01003691, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 11, 2022 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01003691 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →