Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast Cancer
Public ClinicalTrials.gov record NCT01007942. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase III, Double-blind, Placebo-controlled Multicenter Trial of Daily Everolimus in Combination With Trastuzumab and Vinorelbine, in Pretreated Women With HER2/Neu Over-expressing Locally Advanced or Metastatic Breast Cancer.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase III, double-blind, placebo-controlled multinational study will assess the combination everolimus, vinorelbine, and trastuzumab compared to the combination vinorelbine and trastuzumab with respect to progressive-free survival and over survival in HER2/neu positive women with locally advanced or metastatic breast cancer who are resistant to trastuzumab and have been pre-treated with a taxane.
Study identification
- NCT ID
- NCT01007942
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 569 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2009 (Type not available)
- Primary completion
- Jun 2015 (Actual)
- Completion
- Jun 2015 (Actual)
- Last update posted
- Apr 5, 2017
2009 – 2015
United States locations
- U.S. sites
- 43
- U.S. states
- 24
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona / Cancer Center AZ Onc Assoc | Tucson | Arizona | 85724 | — |
| University of Arizona / Cancer Center Deptof Uof A/Arizona Cancer(3) | Tucson | Arizona | 85724 | — |
| University of California San Diego - Moores Cancer Center La Jolla - UCSD Moores Cancer | La Jolla | California | 92093-0658 | — |
| Rocky Mountain Cancer Centers RMCC | Greenwood Village | Colorado | — | — |
| Georgetown University/Lombardi Cancer Center Dept.of Lombardi CancerCtr (3) | Washington D.C. | District of Columbia | 20007-2197 | — |
| Comprehensive Cancer Center - Boca Raton Deerfield Beach | Boca Raton | Florida | 33248 | — |
| Comprehensive Cancer Center - Boca Raton Dept.of BocaRatonCompCanCtr | Boca Raton | Florida | 33248 | — |
| Florida Cancer Specialists DeptofFloridaCancerSpecialists | Fort Myers | Florida | 33916 | — |
| Memorial Hospital Memorial Cancer Institute | Hollywood | Florida | 33021 | — |
| MD Anderson Cancer Center - Orlando Dept.ofMDACC-Orlando(2) | Orlando | Florida | 32806 | — |
| Emory University School of Medicine/Winship Cancer Institute Dept.of WinshipCancerInst. (2) | Atlanta | Georgia | 30322 | — |
| North Shore University Health System NSU | Evanston | Illinois | 60201 | — |
| Kansas City Cancer Center KCCC- South (2) | Overland Park | Kansas | 66210 | — |
| Maryland Oncology Hematology | Owning Mills | Maryland | 21117, | — |
| Park Nicollet Institute Dept. of Park Nicollet | Saint Louis Park | Minnesota | 55416 | — |
| St. Louis University Cancer Center SLU Cancer Center | St Louis | Missouri | 63110 | — |
| University of Nebraska Medical Center Unv Nebraska Med Ctr (2) | Omaha | Nebraska | 68198 | — |
| Comprehensive Cancer Centers of Nevada CCC of Nevada Henderson (4) | Las Vegas | Nevada | 89109 | — |
| Nevada Cancer Institute Dept. of Nevada Cancer (3) | Las Vegas | Nevada | 89135 | — |
| Overlook Hospital - Carol G Simon Cancer Center Carol G Simon | Summit | New Jersey | 07901 | — |
| Clinical Research Alliance Dept.ofArenaOncologyAssoc(2) | Lake Success | New York | 11042 | — |
| Duke University Medical Center Dept. of DUMC (2) | Durham | North Carolina | 27710 | — |
| Northwest Cancer Specialists Tutlatin | Portland | Oregon | 97210 | — |
| University of Pittsburgh Cancer Institute DeptofMageeWomen'sHospital(2) | Pittsburgh | Pennsylvania | 15232 | — |
| The Jones Clinic Dept .of The Jones Clinic (3) | Germantown | Tennessee | 38138 | — |
| Sarah Cannon Research Institute Dept.ofSarahCannonCancerCtr(6) | Nashville | Tennessee | 37203 | — |
| Texas Cancer Center ( Medical City Dallas Hospital) Dept. of Texas Cancer Ctr. (2) | Dallas | Texas | 75230 | — |
| Texas Oncology Presbyterian Hospital (2) | Dallas | Texas | 75246 | — |
| Texas Oncology Texas Onc - Amarillo | Dallas | Texas | 75246 | — |
| Texas Oncology Texas Oncology - Sammons | Dallas | Texas | 75246 | — |
| Texas Oncology Midtown | Dallas | Texas | 75251 | — |
| University of Texas Southwestern Medical Center University of TX SW Med Ctr(2) | Dallas | Texas | 75390-8852 | — |
| University of Texas/MD Anderson Cancer Center SC-5 | Houston | Texas | 77030-4009 | — |
| Baylor College of Medicine Baylor | Houston | Texas | 77030 | — |
| Longview Cancer Center Longview Cancer Center (2) | Longview | Texas | 75601 | — |
| Cancer Care Centers of South Texas / HOAST CCC of So. TX- San Antonio(2) | San Antonio | Texas | 78229 | — |
| South Texas Oncology and Hematology, PA South Texas Oncology (2) | San Antonio | Texas | 78258 | — |
| Tyler Cancer Center Dept.ofTylerCancerCtr. (2) | Tyler | Texas | 75702 | — |
| Utah Cancer Specialists Utah Cancer (2) | Salt Lake City | Utah | 84106 | — |
| Virginia Cancer Specialists Fairfax No.VA (2) | Fairfax | Virginia | 22031 | — |
| Virginia Oncology Associates Dept. of VOA (2) | Norfolk | Virginia | 23502 | — |
| Swedish Cancer Institute Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Green Bay Oncology Green Bay Oncology | Green Bay | Wisconsin | 54301 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 118 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01007942, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 5, 2017 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01007942 live on ClinicalTrials.gov.