The Biology of Resilience
Public ClinicalTrials.gov record NCT01011465. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
The Biology of Resilience: Oxytocin, Social Relationships and Health
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Positive social relationships have consistently been associated with better health, although the neurobiological underpinnings of these observed effects remain largely unknown. The overall goal of the proposed work is to explore novel biological pathways that may explain how social relationships influence health. Recent theorizing suggests that the oxytocin system may underlie some of the observed beneficial effects. Four hypotheses will be examined: 1. Oxytocin ameliorates the deleterious neuroendocrine, cardiovascular, and subjective effects of stress. 2. Oxytocin and social support have similar and additive stress-buffering effects. 3. Effects of oxytocin are evident among younger and older adults. 4. Effects of oxytocin are stronger in women vs men.
Study identification
- NCT ID
- NCT01011465
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 270 participants
Conditions and interventions
Interventions
- intranasal oxytocin Drug
- Placebo Drug
- Social support Behavioral
- No Social Support Behavioral
Drug · Behavioral
Eligibility (public fields only)
- Age range
- 22 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2009
- Primary completion
- Mar 31, 2012
- Completion
- Mar 31, 2012
- Last update posted
- Nov 25, 2012
2009 – 2012
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Harvard School of Public Health | Boston | Massachusetts | 02115 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01011465, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 25, 2012 · Synced Sep 1, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01011465 live on ClinicalTrials.gov.