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Completed Phase 2 Interventional Results available

Study of Everolimus With Paclitaxel and Carboplatin in Patients With Metastatic Melanoma

ClinicalTrials.gov ID: NCT01014351

Public ClinicalTrials.gov record NCT01014351. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 30, 2026, 2:30 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Study of Everolimus in Combination With Paclitaxel and Carboplatin in Patients With Metastatic Melanoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Based on data demonstrating synergy between paclitaxel and mammalian target of rapamycin (mTOR) inhibition, the investigators propose that the addition of everolimus to paclitaxel with carboplatin should lead to improvements in efficacy as measured by progression-free survival and response rate.

Study identification

NCT ID
NCT01014351
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
70 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 2010 (Type not available)
Primary completion
Feb 2012 (Actual)
Completion
Aug 2013 (Actual)
Last update posted
Mar 26, 2014

2010 – 2013

United States locations

U.S. sites
12
U.S. states
11
U.S. cities
12
Facility City State ZIP Site status
Florida Cancer Specialists Fort Myers Florida 33901 —
Northeast Georgia Medical Center Gainesville Georgia 30501 —
Oncology Hematology of SW Indiana Evansville Indiana 47630 —
Hematology Oncology Clinic, LLP Baton Rouge Louisiana 70809 —
Center for Cancer and Blood Disorders Bethesda Maryland 20817 —
Grand Rapids Oncology Program Grand Rapids Michigan 49503 —
Research Medical Center Kansas City Missouri 64132 —
Nebraska Methodist Cancer Center Omaha Nebraska 68114 —
Oncology Hematology Care Cincinnati Ohio 45242 —
Chattanooga Oncology Hematology Associates Chattanooga Tennessee 37404 —
Tennessee Oncology, PLLC Nashville Tennessee 37023 —
Peninsula Cancer Institute Newport News Virginia 23601 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01014351, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 26, 2014 · Synced Sep 30, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01014351 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →