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Completed Phase 2 Interventional Results available

A Study of AMNN107 in the Treatment of Metastatic and/or Inoperable Melanoma Harboring a c-Kit Mutation

ClinicalTrials.gov ID: NCT01028222

Public ClinicalTrials.gov record NCT01028222. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 9:55 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

The TEAM Trial (Tasigna Efficacy in Advanced Melanoma): A Phase II, Open Label, Multi-center, Single-arm Study to Assess the Efficacy of Tasigna ® in the Treatment of Patients With Metastatic and/or Inoperable Melanoma Harboring a c-Kit Mutation

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine whether nilotinib is efficacious in the treatment of metastatic and/or inoperable melanoma harboring a c-Kit mutation.

Study identification

NCT ID
NCT01028222
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
55 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2010 (Type not available)
Primary completion
Dec 2014 (Actual)
Completion
Dec 2014 (Actual)
Last update posted
Dec 30, 2015

2010 – 2014

United States locations

U.S. sites
14
U.S. states
10
U.S. cities
14
Facility City State ZIP Site status
City of Hope National Medical Center City of Hope national Med Ctr Duarte California 91010-3000 —
University of California San Diego - Moores Cancer Center UCSD Moores Cancer Center La Jolla California 92093-0658 —
University of California at Los Angeles UCLA Los Angeles California 90024 —
California Pacific Medical Center California Pacific Med San Francisco California 94120-7999 —
University of Colorado Univ Colorado 2 Aurora Colorado 80045 —
Rush University Medical Center SC Chicago Illinois 60612 —
Oncology Specialists, SC Dept.of Oncology Specialists Park Ridge Illinois 60068-0736 —
Sidney Kimmel Comprehensive Cancer Center/Johns Hopkins Med. Medical Oncology Baltimore Maryland 21231 —
Dana Farber Cancer Institute DFCI - Brookline Boston Massachusetts 02215 —
Mayo Clinic - Rochester Mayo Clinic- Gonda Rochester Minnesota 55905 —
Washington University School of Medicine CAMN107B2301 St Louis Missouri 63110 —
Memorial Sloan Kettering Cancer Center New York New York 10021 —
Case Western Reserve Case Western Cleveland Ohio 44106-5000 —
Baylor Health Care System/Sammons Cancer Center Baylor 2 Dallas Texas 75246 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01028222, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 30, 2015 · Synced Oct 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01028222 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →