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Completed Phase 3 Interventional Results available

A Phase III Randomized, Double Blind, Placebo Controlled Multi-center Study of Panobinostat for Maintenance of Response in Patients With Hodgkin's Lymphoma (HL)

ClinicalTrials.gov ID: NCT01034163

Public ClinicalTrials.gov record NCT01034163. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 10, 2026, 1:19 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III Randomized, Double Blind, Placebo Controlled Multi-center Study of Panobinostat for Maintenance of Response in Patients With Hodgkin's Lymphoma Who Are at Risk for Relapse After High Dose Chemotherapy and Autologous Stem Cell Transplant (ASCT)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective was to provide drug to ongoing patients who were receiving panobinostat and to characterize the safety and tolerability of panobinostat in patients with HL after achieving a complete response following autologous hematopoietic stem cell transplant (AHSCT) with high dose chemotherapy (HDT). Primary objective as stated above reflects a change from the original protocol as of an amendment. The original objective was no longer feasible with only 41 of 367 patients randomized after the study was halted due to poor recruitment. An amendment was written to allow patients on panobinostat to continue their treatment until discontinuation/completion criteria were met (patients were unblinded). Therefore, the study was completed as per this amendment. No secondary objectives were included for this trial from the amendment; this was a change from the original protocol.

Study identification

NCT ID
NCT01034163
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
41 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2010
Primary completion
Apr 30, 2012
Completion
Apr 30, 2012
Last update posted
Jul 6, 2016

2010 – 2012

United States locations

U.S. sites
13
U.S. states
11
U.S. cities
11
Facility City State ZIP Site status
Cedars Sinai Medical Center Los Angeles California 90048
University of California at Los Angeles Los Angeles California 90095
Georgia Health Sciences University Medical College of Georgia Augusta Georgia 30912
Northwestern University Oncology Chicago Illinois 60611-3308
Indiana University Indianapolis Indiana 46202
Massachusetts General Hospital Boston Massachusetts 02114
Dana-Farber Cancer Institute Dana-Farber Cancer Institute Boston Massachusetts 02115
Mayo Clinic - Rochester Hematology/Oncology Dept. Rochester Minnesota 55905
Duke University Medical Center Durham North Carolina 27710
Medical University of South Carolina Oncology Charleston South Carolina 29425
Vanderbilt University Medical Center Vanderbilt Clinic - Oncology Nashville Tennessee 37232
Mary Babb Randolph Cancer Center Morgantown West Virginia 26506-9162
Medical College of Wisconsin Oncology Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01034163, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 6, 2016 · Synced Sep 10, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01034163 live on ClinicalTrials.gov.

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