Study of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder
Public ClinicalTrials.gov record NCT01052077. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study of the Safety and Efficacy of OPDC-34712 (1 to 3 mg/Day) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Double-blind study wherein patients with Major Depressive Disorder (MDD) will receive either from 1 to 3 mg a day of study medication (OPC-34712)or placebo (an inactive substance) in addition to an FDA approved antidepressant in order to determine if the study medication is effective as an add on treatment of MDD.
Study identification
- NCT ID
- NCT01052077
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 773 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2010
- Primary completion
- Sep 30, 2011
- Completion
- Oct 31, 2011
- Last update posted
- Nov 1, 2015
2010 – 2011
United States locations
- U.S. sites
- 43
- U.S. states
- 21
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Pacific Clinical Research Medical Group | Arcadia | California | 91007 | — |
| Southwestern Research | Beverly Hills | California | 90210 | — |
| Excell Research | Oceanside | California | 92056 | — |
| Affiliated Research Institute | San Diego | California | 92108 | — |
| Neuropsychiatric Research Center of Orange County | Santa Ana | California | 92782 | — |
| California Neuroscience Research Medical Group, Inc. | Sherman Oaks | California | 91403 | — |
| CNS Clinical Research Group | Coral Springs | Florida | 33067 | — |
| Gulfcoast Clinical Research Center | Fort Myers | Florida | 33912 | — |
| Clinical Neuroscience Solutions, Inc. | Jacksonville | Florida | 32216 | — |
| Scientific Clinical Research, Inc. | North Miami | Florida | 33161 | — |
| Clinical Neuroscience Solutions, Inc. | Orlando | Florida | 32806 | — |
| Comprehensive NeuroScience, Inc. | Atlanta | Georgia | 30328 | — |
| Carman Research | Smyrna | Georgia | 30080 | — |
| Goldpoint Clinical Research, LLC | Indianapolis | Indiana | 46260 | — |
| Vince and Associates Clinical Research | Overland Park | Kansas | 66212 | — |
| Clinical InSights | Glen Burnie | Maryland | 21061 | — |
| Pharmasite Research, Inc. | Pikesville | Maryland | 21208 | — |
| MSU/Institute for Health Studies | East Lansing | Michigan | 48824 | — |
| Center for Emotional Fitness | Cherry Hill | New Jersey | 08002 | — |
| Neurobehavioral Research, Inc. | Cedarhurst | New York | 11515 | — |
| Eastside Comprehensive Medical Center | New York | New York | 10021 | — |
| Medical & Behavioral Health Research, PC | New York | New York | 10023 | — |
| Finger Lakes Clinical Research | Rochester | New York | 14618 | — |
| Richmond Behavioral Associates | Staten Island | New York | 10312 | — |
| Northcoast Clinical Trials | Beachwood | Ohio | 44122 | — |
| Patient Priority Clinical sites, LLC | Cincinnati | Ohio | 45242 | — |
| Midwest Clinical Research Center | Dayton | Ohio | 45408 | — |
| IPS Research Company | Oklahoma City | Oklahoma | 73103 | — |
| Summit Research Network (Oregon), LLC | Portland | Oregon | 97210 | — |
| City Line Avenue Family Practice | Bala-Cynwyd | Pennsylvania | 19004 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Lincoln Research | Lincoln | Rhode Island | 02865 | — |
| Clinical NeuroScience Solutions, Inc. | Memphis | Tennessee | 38119 | — |
| FutureSearch Trials | Austin | Texas | 78756 | — |
| FutureSearch Trials of Dallas | Dallas | Texas | 75231 | — |
| Clinical Trials of Texas | San Antonio | Texas | 78229 | — |
| Radiant Research | Salt Lake City | Utah | 84107 | — |
| Psychiatric Alliance of The Blue Ridge | Charlottesville | Virginia | 22903 | — |
| NeuroScience, Inc. | Herndon | Virginia | 20170 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
| Summit Research Network (Seattle), LLC | Seattle | Washington | 98104 | — |
| Northbrooke Research Center | Brown Deer | Wisconsin | 53223 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01052077, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 1, 2015 · Synced Sep 27, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01052077 live on ClinicalTrials.gov.