A Study of the Effect of Dalcetrapib on Artherosclerotic Disease in Patients With Coronary Artery Disease
Public ClinicalTrials.gov record NCT01059682. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center, Double-blind, Randomized, Placebo Controlled, Parallel Group Study of the Effect of Dalcetrapib on Atherosclerotic Disease Progression As Measured by Coronary Intravascular Ultrasound, Carotid B-Mode Ultrasound and Coronary Angiography
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This multicenter, double-blind, randomized, placebo-controlled study will evaluate the effect of dalcetrapib 600 mg on artherosclerotic disease progression, lipid profile and biomarker profile and long-term safety profile of dalcetrapib in patients with coronary artery disease. Atherosclerotic disease progression will be measured 1. Coronary Intravascular Ultrasound (IVUS), Quantitative Coronary Angiography 2. Carotid B-Mode Ultrasound Intima Medial Thickness (IMT) and total plaque volume in subjects undergoing coronary angiography who have coronary artery disease (CAD). Patients will be randomized to receive dalcetrapib 600 mg orally once a day or placebo. The anticipated time on study treatment will be 24 months. The target sample size is 800-1000 patients.
Study identification
- NCT ID
- NCT01059682
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 936 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2009
- Primary completion
- Aug 31, 2011
- Completion
- Aug 31, 2011
- Last update posted
- Mar 23, 2020
2010 – 2011
United States locations
- U.S. sites
- 41
- U.S. states
- 22
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Los Angeles | California | 90033 | — |
| Not listed | Los Angeles | California | 90073 | — |
| Not listed | Torrance | California | 90502 | — |
| Not listed | Boulder | Colorado | 80304 | — |
| Not listed | Greeley | Colorado | 80631 | — |
| Not listed | Littleton | Colorado | 80120 | — |
| Not listed | Hartford | Connecticut | 06115 | — |
| Not listed | Atlantis | Florida | 33462 | — |
| Not listed | Fort Lauderdale | Florida | 33308 | — |
| Not listed | Fort Lauderdale | Florida | 33316 | — |
| Not listed | Jacksonville | Florida | 32216 | — |
| Not listed | Miami | Florida | 33137 | — |
| Not listed | Sarasota | Florida | 34239 | — |
| Not listed | Tampa | Florida | 33609 | — |
| Not listed | Decatur | Georgia | 30033 | — |
| Not listed | Chicago | Illinois | 60637-1470 | — |
| Not listed | Elkhart | Indiana | 46514 | — |
| Not listed | Louisville | Kentucky | 40205 | — |
| Not listed | Columbia | Maryland | 21044 | — |
| Not listed | Salisbury | Maryland | 21804 | — |
| Not listed | Boston | Massachusetts | 02114 | — |
| Not listed | Ann Arbor | Michigan | 48109-0666 | — |
| Not listed | Kalamazoo | Michigan | 49048 | — |
| Not listed | Midland | Michigan | 48670 | — |
| Not listed | Muskegon | Michigan | 49444 | — |
| Not listed | Petoskey | Michigan | 49770 | — |
| Not listed | Duluth | Minnesota | 55805 | — |
| Not listed | Rochester | Minnesota | 55905 | — |
| Not listed | Kansas City | Missouri | 64114 | — |
| Not listed | Paramus | New Jersey | 07652 | — |
| Not listed | New York | New York | 10011 | — |
| Not listed | Rochester | New York | 14642 | — |
| Not listed | Chapel Hill | North Carolina | 27599 | — |
| Not listed | Toledo | Ohio | 43614 | — |
| Not listed | Hershey | Pennsylvania | 17033 | — |
| Not listed | Providence | Rhode Island | 02906 | — |
| Not listed | Germantown | Tennessee | 38138 | — |
| Not listed | Oak Ridge | Tennessee | 37830 | — |
| Not listed | Dallas | Texas | 75216 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | Richmond | Virginia | 23249 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 69 non-U.S. sites.
Recently updated Cardiovascular Disease trials
Other public records listing Cardiovascular Disease. Sorted by last update posted; newest first. Not a recommendation.
- NCT07518719: Feasibility of The Health Integrated Nutrition and Kidney Wellness Program Recruiting
- NCT03372733: Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults Recruiting
- NCT07783802: A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event Not yet recruiting
- NCT07748858: Improving Patient-Centered Care for Underserved Older African American Patients With Cardiovascular Comorbidities Recruiting
- NCT07087184: Gauging Outcomes of Total Milk Ingestion on Lipid and gControl Recruiting
- NCT03127631: A Study for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients Active, not recruiting
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01059682, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 23, 2020 · Synced Sep 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01059682 live on ClinicalTrials.gov.