ClinicalTrials.gov record
JC Virus Antibody Study of Participants With Relapsing Forms of MS Receiving Treatment With Natalizumab
ClinicalTrials.gov ID: NCT01070836
Public ClinicalTrials.gov record NCT01070836. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
JCV Antibody Program in Patients With Relapsing Multiple Sclerosis Receiving or Considering Treatment With Tysabri: STRATIFY-2
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to demonstrate that the incidence of progressive multifocal Leukoencephalopathy (PML) in natalizumab-treated participants who do not have detectable antibodies to John Cunningham virus (JCV) (antibody negative) is lower than in participants who have detectable antibodies to JCV (antibody positive). The secondary objectives of this study are to: Estimate the incidence of PML in natalizumab-treated participants who are anti-JCV antibody negative and anti-JCV antibody positive, based on a meta-analysis of data obtained from this study and other data sources; Define the prevalence of anti-JCV antibody in relapsing multiple sclerosis (MS) participants receiving natalizumab within the TYSABRI Outreach: United Commitment to Health (TOUCH) Prescribing Program; Determine changes in anti-JCV antibody status over time.
Study identification
- NCT ID
- NCT01070836
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 35,895 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2010 (Type not available)
- Primary completion
- Nov 2015 (Actual)
- Completion
- Nov 2015 (Actual)
- Last update posted
- Sep 29, 2016
2010 – 2015
United States locations
- U.S. sites
- 473
- U.S. states
- 51
- U.S. cities
- 389
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35209 | — |
| Research Site | Birmingham | Alabama | 35233 | — |
| Research Site | Cullman | Alabama | 35058 | — |
| Research Site | Tucaloosa | Alabama | 35406 | — |
| Research Site | Anchorage | Alaska | 99508 | — |
| Research Site | Flagstaff | Arizona | 86001 | — |
| Research Site | Gilbert | Arizona | 85234 | — |
| Research Site | Phoenix | Arizona | 85004 | — |
| Research Site | Phoenix | Arizona | 85013 | — |
| Research Site | Phoenix | Arizona | 85018 | — |
| Research Site | Phoenix | Arizona | 85032 | — |
| Research Site | Scottsdale | Arizona | 85258 | — |
| Research Site | Tucson | Arizona | 85718 | — |
| Research Site | Tucson | Arizona | 85741 | — |
| Research Site | Fayetteville | Arkansas | 72703 | — |
| Research Site | Little Rock | Arkansas | 72205 | — |
| Research Site | Sherwood | Arkansas | 72120 | — |
| Research Site | Auburn | California | 95602 | — |
| Research Site | Berkeley | California | 94705 | — |
| Research Site | Carmel | California | 93923 | — |
| Research Site | Carmichael | California | 95608 | — |
| Research Site | Fountain Valley | California | 92708 | — |
| Research Site | Fresno | California | 93701 | — |
| Research Site | Fresno | California | 93720 | — |
| Research Site | Fullerton | California | 92835 | — |
| Research Site | La Jolla | California | 92037 | — |
| Research Site | Loma Linda | California | 92354 | — |
| Research Site | Los Alamitos | California | 90720 | — |
| Research Site | Los Angeles | California | 90033 | — |
| Research Site | Los Angeles | California | 90073 | — |
| Research Site | Marina del Rey | California | 90292 | — |
| Research Site | Modesto | California | 95355 | — |
| Research Site | Newport Beach | California | 92663 | — |
| Research Site | Northridge | California | 91328 | — |
| Research Site | Palo Alto | California | 94301 | — |
| Research Site | Pasadena | California | 91101 | — |
| Research Site | Pasadena | California | 91105 | — |
| Research Site | Redding | California | 96001 | — |
| Research Site | Sacramento | California | 95816 | — |
| Research Site | San Diego | California | 82117 | — |
| Research Site | San Francisco | California | 94109 | — |
| Research Site | San Francisco | California | 94115 | — |
| Research Site | San Francisco | California | 94117 | — |
| Research Site | Santa Barbara | California | 93105 | — |
| Research Site | St. Helena | California | 94574 | — |
| Research Site | Stanford | California | 94305 | — |
| Research Site | Stockton | California | 95204 | — |
| Research Site | Thousand Oaks | California | 91360 | — |
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| Research Site | Arvada | Colorado | 80002 | — |
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| Research Site | Basalt | Colorado | 81621 | — |
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| Research Site | Colorado Springs | Colorado | 80907 | — |
| Research Site | Colorado Springs | Colorado | 80920 | — |
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| Research Site | New Haven | Connecticut | 06510 | — |
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| Research Site | Norwich | Connecticut | 06360 | — |
| Research Site | Dover | Delaware | 19901 | — |
| Research Site | Newark | Delaware | 19713 | — |
| Research Site | Washington D.C. | District of Columbia | 20007 | — |
| Research Site | Washington D.C. | District of Columbia | 20037 | — |
| Research Site | Bradenton | Florida | 34205 | — |
| Research Site | Clearwater | Florida | 33756 | — |
| Research Site | Fort Lauderdale | Florida | 33308 | — |
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| Research Site | Orlando | Florida | 32806 | — |
| Research Site | Ormond Beach | Florida | 32174 | — |
| Research Site | Palm Bay | Florida | 32905 | — |
| Research Site | Palm Beach Gardens | Florida | 33410 | — |
| Research Site | Pompano Beach | Florida | 33060 | — |
| Research Site | Ponte Vedra Beach | Florida | 32082 | — |
| Research Site | Port Charlotte | Florida | 33952 | — |
| Research Site | Sarasota | Florida | 34239 | — |
| Research Site | Sarasota | Florida | 34243 | — |
| Research Site | St. Petersburg | Florida | 33705 | — |
| Research Site | St. Petersburg | Florida | 33713 | — |
| Research Site | Sunrise | Florida | 33351 | — |
| Research Site | Tallahassee | Florida | 32308 | — |
| Research Site | Tampa | Florida | 33609 | — |
| Research Site | Tampa | Florida | 33612 | — |
| Research Site | Vero Beach | Florida | 32960 | — |
| Research Site | Winter Haven | Florida | 33880 | — |
| Research Site | Winter Park | Florida | 32792 | — |
| Research Site | Athens | Georgia | 30606 | — |
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| Research Site | Atlanta | Georgia | 30327 | — |
| Research Site | Columbus | Georgia | 31909 | — |
| Research Site | Johns Creek | Georgia | 30097 | — |
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| Research Site | Honolulu | Hawaii | 96813 | — |
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| Research Site | Bloomington | Illinois | 61701 | — |
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| Research Site | Champaign | Illinois | 61820 | — |
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| Research Site | Chicago | Illinois | 60637 | — |
| Research Site | Elk Grove Village | Illinois | 60007 | — |
| Research Site | Elmhurst | Illinois | 60126 | — |
| Research Site | Evanston | Illinois | 60201 | — |
| Research Site | Flossmoor | Illinois | 60422 | — |
| Research Site | Herrin | Illinois | 62948 | — |
| Research Site | Lake Barrington | Illinois | 60010 | — |
| Research Site | Lombard | Illinois | 60148 | — |
| Research Site | Melrose Park | Illinois | 60160 | — |
| Research Site | Niles | Illinois | 60714 | — |
| Research Site | North Aurora | Illinois | 60542 | — |
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| Research Site | Peoria | Illinois | 61606 | — |
| Research Site | St. Charles | Illinois | 60175 | — |
| Research Site | Anderson | Indiana | 46016 | — |
| Research Site | Bloomington | Indiana | 47403 | — |
| Research Site | Elkhart | Indiana | 46514 | — |
| Research Site | Evansville | Indiana | 47715 | — |
| Research Site | Fort Wayne | Indiana | 76845 | — |
| Research Site | Indianapolis | Indiana | 46256 | — |
| Research Site | Indianapolis | Indiana | 46260 | — |
| Research Site | Lafayette | Indiana | 47905 | — |
| Research Site | Merrillville | Indiana | 46410 | — |
| Research Site | Mishawaka | Indiana | 46545 | — |
| Research Site | Valparaiso | Indiana | 46383 | — |
| Research Site | Ames | Iowa | 80010 | — |
| Research Site | Des Moines | Iowa | 50309 | — |
| Research Site | Des Moines | Iowa | 50314 | — |
| Research Site | Iowa City | Iowa | 52242 | — |
| Research Site | West Burlington | Iowa | 52655 | — |
| Research Site | Hays | Kansas | 67601 | — |
| Research Site | Kansas City | Kansas | 66160 | — |
| Research Site | Lenexa | Kansas | 66214 | — |
| Research Site | Overland Park | Kansas | 66212 | — |
| Research Site | Topeka | Kansas | 66606 | — |
| Research Site | Wichita | Kansas | 67206 | — |
| Research Site | Wichita | Kansas | 67208 | — |
| Research Site | Wichita | Kansas | 67214 | — |
| Research Site | Lexington | Kentucky | 40513 | — |
| Research Site | Lexington | Kentucky | 40536 | — |
| Research Site | Louisville | Kentucky | 40207 | — |
| Research Site | Paducah | Kentucky | 42003 | — |
| Research Site | Alexandria | Louisiana | 71301 | — |
| Research Site | Baton Rouge | Louisiana | 70809 | — |
| Research Site | Baton Rouge | Louisiana | 70810 | — |
| Research Site | Lacombe | Louisiana | 70445 | — |
| Research Site | Lafayette | Louisiana | 70506 | — |
| Research Site | New Orleans | Louisiana | 70112 | — |
| Research Site | New Orleans | Louisiana | 70115 | — |
| Research Site | Shreveport | Louisiana | 71103 | — |
| Research Site | Belfast | Maine | 04915 | — |
| Research Site | Lewiston | Maine | 04240 | — |
| Research Site | Scarborough | Maine | 04074 | — |
| Research Site | Westbrook | Maine | 04092 | — |
| Research Site | Annapolis | Maryland | 21401 | — |
| Research Site | Baltimore | Maryland | 21201 | — |
| Research Site | Baltimore | Maryland | 21287 | — |
| Research Site | Bethesda | Maryland | 20814 | — |
| Research Site | Frederick | Maryland | 21702 | — |
| Research Site | Hagerstown | Maryland | 21742 | — |
| Research Site | Attleboro | Massachusetts | 02703 | — |
| Research Site | Boston | Massachusetts | 02111 | — |
| Research Site | Boston | Massachusetts | 02135 | — |
| Research Site | Boston | Massachusetts | 02215 | — |
| Research Site | Brookline | Massachusetts | 02445 | — |
| Research Site | Burlington | Massachusetts | 01805 | — |
| Research Site | Milford | Massachusetts | 01757 | — |
| Research Site | Peabody | Massachusetts | 01960 | — |
| Research Site | Springfield | Massachusetts | 01104 | — |
| Research Site | Worcester | Massachusetts | 01605 | — |
| Research Site | Ann Arbor | Michigan | 48109 | — |
| Research Site | Bingham Farms | Michigan | 48025 | — |
| Research Site | Cinton Township | Michigan | 48035 | — |
| Research Site | Detroit | Michigan | 48201 | — |
| Research Site | Detroit | Michigan | 48202 | — |
| Research Site | East Lansing | Michigan | 48824 | — |
| Research Site | Farmington Hills | Michigan | 48334 | — |
| Research Site | Grand Rapids | Michigan | 49525 | — |
| Research Site | Kalamazoo | Michigan | 49007 | — |
| Research Site | Kalamazoo | Michigan | 49048 | — |
| Research Site | Midland | Michigan | 48640 | — |
| Research Site | Muskegon | Michigan | 49444 | — |
| Research Site | Rochester Hills | Michigan | 48307 | — |
| Research Site | Roseville | Michigan | 48066 | — |
| Research Site | Saginaw | Michigan | 48604 | — |
| Research Site | Southfield | Michigan | 48034 | — |
| Research Site | Traverse City | Michigan | 49684 | — |
| Research Site | West Bloomfield | Michigan | 48322 | — |
| Research Site | Woodhaven | Michigan | 48183 | — |
| Research Site | Golden Valley | Minnesota | 55422 | — |
| Research Site | Minneapolis | Minnesota | 55404 | — |
| Research Site | Minneapolis | Minnesota | 55414 | — |
| Research Site | Rochester | Minnesota | 55905 | — |
| Research Site | Greenwood | Mississippi | 38930 | — |
| Research Site | Hattiesburg | Mississippi | 39401 | — |
| Research Site | Tupelo | Mississippi | 38801 | — |
| Research Site | Kansas City | Missouri | 64111 | — |
| Research Site | Nixa | Missouri | 65714 | — |
| Research Site | Springfield | Missouri | 65807 | — |
| Research Site | St Louis | Missouri | 63104 | — |
| Research Site | St Louis | Missouri | 63110 | — |
| Research Site | St Louis | Missouri | 63131 | — |
| Research Site | St Louis | Missouri | 63141 | — |
| Research Site | Washington | Missouri | 63090 | — |
| Research Site | Billings | Montana | 59101 | — |
| Research Site | Great Falls | Montana | 59405 | — |
| Research Site | Missoula | Montana | 59802 | — |
| Research Site | Hastings | Nebraska | 68901 | — |
| Research Site | Lincoln | Nebraska | 68521 | — |
| Research Site | Norfolk | Nebraska | 68701 | — |
| Research Site | North Platte | Nebraska | 69101 | — |
| Research Site | Omaha | Nebraska | 68131 | — |
| Research Site | Omaha | Nebraska | 68198 | — |
| Research Site | Scottsbluff | Nebraska | 69361 | — |
| Research Site | Las Vegas | Nevada | 89102 | — |
| Research Site | Reno | Nevada | 89502 | — |
| Research Site | Reno | Nevada | 89509 | — |
| Research Site | Lebanon | New Hampshire | 03766 | — |
| Research Site | Bayonne | New Jersey | 07002 | — |
| Research Site | Denville | New Jersey | 07834 | — |
| Research Site | Edison | New Jersey | 08820 | — |
| Research Site | Flemington | New Jersey | 08822 | — |
| Research Site | Freehold | New Jersey | 07728 | — |
| Research Site | Lawrenceville | New Jersey | 08648 | — |
| Research Site | Livingston | New Jersey | 07039 | — |
| Research Site | New Brunswick | New Jersey | 08901 | — |
| Research Site | Newark | New Jersey | 07103 | — |
| Research Site | Paterson | New Jersey | 07503 | — |
| Research Site | Stratford | New Jersey | 08084 | — |
| Research Site | Teaneck | New Jersey | 07666 | — |
| Research Site | West Long Branch | New Jersey | 07764 | — |
| Research Site | Albuquerque | New Mexico | 87106 | — |
| Research Site | Albany | New York | 12205 | — |
| Research Site | Albany | New York | 12206 | — |
| Research Site | Albany | New York | 12208 | — |
| Research Site | Amherst | New York | 14226 | — |
| Research Site | Bay Shore | New York | 11706 | — |
| Research Site | Brooklyn | New York | 11215 | — |
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| Research Site | Buffalo | New York | 14203 | — |
| Research Site | Camillus | New York | 13031 | — |
| Research Site | Cedarhurst | New York | 11516 | — |
| Research Site | Corning | New York | 14830 | — |
| Research Site | East Meadow | New York | 11554 | — |
| Research Site | East Syracuse | New York | 13057 | — |
| Research Site | Flushing | New York | 11365 | — |
| Research Site | Fresh Meadows | New York | 11365 | — |
| Research Site | Great Neck | New York | 11021 | — |
| Research Site | Kingston | New York | 12401 | — |
| Research Site | Lake Success | New York | 11042 | — |
| Research Site | Latham | New York | 12110 | — |
| Research Site | Mineola | New York | 11501 | — |
| Research Site | Mount Kisco | New York | 10549 | — |
| Research Site | New Hyde Park | New York | 11040 | — |
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| Research Site | New York | New York | 10019 | — |
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| Research Site | Newark | New York | 14513 | — |
| Research Site | Patchogue | New York | 11772 | — |
| Research Site | Plainview | New York | 11803 | — |
| Research Site | Poughkeepsie | New York | 12601 | — |
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| Research Site | Rochester | New York | 14642 | — |
| Research Site | Rye Brook | New York | 10573 | — |
| Research Site | Schenectady | New York | 12308 | — |
| Research Site | Staten Island | New York | 10306 | — |
| Research Site | Stony Brook | New York | 11794 | — |
| Research Site | Syracuse | New York | 13210 | — |
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| Research Site | Advance | North Carolina | 27006 | — |
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| Research Site | Charlotte | North Carolina | 28204 | — |
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| Research Site | Concord | North Carolina | 28025 | — |
| Research Site | Durham | North Carolina | 37710 | — |
| Research Site | Greensboro | North Carolina | 27405 | — |
| Research Site | Greenville | North Carolina | 27834 | — |
| Research Site | Henderson | North Carolina | 27536 | — |
| Research Site | Hendersonville | North Carolina | 28792 | — |
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| Research Site | Bismarck | North Dakota | 58501 | — |
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| Research Site | East Providence | Rhode Island | 02914 | — |
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| Research Site | Mt. Pleasant | South Carolina | 29464 | — |
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| Research Site | Silverdale | Washington | 98383 | — |
| Research Site | Spokane | Washington | 99202 | — |
| Research Site | Spokane | Washington | 99204 | — |
| Research Site | Spokane | Washington | 99208 | — |
| Research Site | Tacoma | Washington | 98405 | — |
| Research Site | Wenatchee | Washington | 98801 | — |
| Research Site | Huntington | West Virginia | 25702 | — |
| Research Site | Point Pleasant | West Virginia | 25550 | — |
| Research Site | Green Bay | Wisconsin | 54301 | — |
| Research Site | Green Bay | Wisconsin | 54308 | — |
| Research Site | La Crosse | Wisconsin | 54601 | — |
| Research Site | Madison | Wisconsin | 53715 | — |
| Research Site | Milwaukee | Wisconsin | 53215 | — |
| Research Site | Milwaukee | Wisconsin | 53226 | — |
| Research Site | Neenah | Wisconsin | 54956 | — |
| Research Site | Waukesha | Wisconsin | 53188 | — |
| Research Site | Cheyenne | Wyoming | 82001 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01070836, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 29, 2016 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01070836 live on ClinicalTrials.gov.