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Completed Phase 2 Interventional

Safety and Cognitive Function Study of EVP-6124 in Patients With Mild to Moderate Alzheimer's Disease

ClinicalTrials.gov ID: NCT01073228

Public ClinicalTrials.gov record NCT01073228. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 7:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-Controlled, Parallel, 24-Week, Phase 2 Study of Three Different Doses of an Alpha-7 Nicotinic Acetylcholine Receptor Agonist (EVP-6124) or Placebo in Subjects With Mild to Moderate Probable Alzheimer's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is being conducted to determine the safety and effect on cognitive function of the investigational medication, EVP-6124, in individuals with mild to moderate probable Alzheimer's disease.

Study identification

NCT ID
NCT01073228
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
FORUM Pharmaceuticals Inc
Industry
Enrollment
409 participants

Conditions and interventions

Eligibility (public fields only)

Age range
50 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2010
Primary completion
Oct 31, 2011
Completion
Jan 31, 2012
Last update posted
Apr 24, 2014

2010 – 2012

United States locations

U.S. sites
25
U.S. states
11
U.S. cities
24
Facility City State ZIP Site status
HOPE Research Institute Phoenix Arizona 85050
Catalina Research Institute Chino California 91710
ATP Clinical Research Costa Mesa California 92626
University of California, Irvine Orange California 92868
Radiant Research Santa Rosa California 95405
Research Center for Clinical Studies, Inc. Norwalk Connecticut 06851
Chase Medical Research, LLC Waterbury Connecticut 06708
Meridien Research Brooksville Florida 34601
Brain Matters Research Delray Beach Florida 33445
MD Clinical Hallandale Florida 33009
Galiz Research Miami Springs Florida 33166
Renstar Medical Research Ocala Florida 34471
Compass Research, LLC Orlando Florida 32806
Princeton Medical Institute Princeton New Jersey 08540
Memory Enhancement Center of NJ Toms River New Jersey 08755
Brooklyn Medical Institute Brooklyn New York 11214
Social Psychiatry Research Institute Brooklyn New York 11235
Advanced Bio Behavioral Sciences Inc. Elmsford New York 10523
University of Rochester Medical Center at MCH Rochester New York 14620
Columbus Research and Wellness Institute Columbus Ohio 31909
Summit Research Network Portland Oregon 97210
FutureSearch Trials of Dallas, L.P. Dallas Texas 75231
Grayline Clinical Drug Trials Wichita Falls Texas 76309
The Memory Clinic Bennington Vermont 05201
The Center for Excellence in Aging and Geriatric Health Williamsburg Virginia 23185

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01073228, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 24, 2014 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01073228 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →