A Randomized Study to Evaluate the Safety, Tolerability and Antiviral Activity of ABT-450, ABT-333 and ABT-072
Public ClinicalTrials.gov record NCT01074008. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Blinded, Randomized, Placebo-controlled, Dose Ranging Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Multiple Doses of ABT-450 With Ritonavir (ABT-450/r), ABT-333 or ABT-072 Each Administered Alone and in Combination With Peginterferon α-2a and Ribavirin (PegIFN/RBV) in Treatment-Naïve Subjects With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection
Study identification
- NCT ID
- NCT01074008
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- AbbVie (prior sponsor, Abbott)
- Industry
- Enrollment
- 74 participants
Conditions and interventions
Interventions
- ABT-072 Drug
- ABT-333 Drug
- ABT-450 Drug
- Peginterferon alpha-2a Drug
- Placebo Other
- Ribavirin Drug
- Ritonavir Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2010
- Primary completion
- May 31, 2011
- Completion
- Dec 31, 2011
- Last update posted
- Jan 7, 2015
2010 – 2012
United States locations
- U.S. sites
- 25
- U.S. states
- 16
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Site Reference ID/Investigator# 23392 | Phoenix | Arizona | 85054 | — |
| Site Reference ID/Investigator# 23370 | Anaheim | California | 92801 | — |
| Site Reference ID/Investigator# 23387 | La Jolla | California | 92037 | — |
| Site Reference ID/Investigator# 23388 | Los Angeles | California | 90048 | — |
| Site Reference ID/Investigator# 23371 | Aurora | Colorado | 80045 | — |
| Site Reference ID/Investigator# 23369 | Orlando | Florida | 32803 | — |
| Site Reference ID/Investigator# 26362 | Orlando | Florida | 32809 | — |
| Site Reference ID/Investigator# 23373 | Chicago | Illinois | 60611 | — |
| Site Reference ID/Investigator# 24908 | Chicago | Illinois | 60612 | — |
| Site Reference ID/Investigator# 23381 | Indianapolis | Indiana | 46202-5121 | — |
| Site Reference ID/Investigator# 23372 | Baton Rouge | Louisiana | 70810 | — |
| Site Reference ID/Investigator# 24710 | New Orleans | Louisiana | 70112 | — |
| Site Reference ID/Investigator# 23391 | Baltimore | Maryland | 21287 | — |
| Site Reference ID/Investigator# 23377 | Detroit | Michigan | 48202 | — |
| Site Reference ID/Investigator# 24909 | Saint Paul | Minnesota | 55114 | — |
| Site Reference ID/Investigator# 35842 | New York | New York | 10016 | — |
| Site Reference ID/Investigator# 23379 | New York | New York | 10021 | — |
| Site Reference ID/Investigator# 23375 | Chapel Hill | North Carolina | 27599-7584 | — |
| Site Reference ID/Investigator# 23385 | Durham | North Carolina | 27705 | — |
| Site Reference ID/Investigator# 23376 | Dallas | Texas | 75203 | — |
| Site Reference ID/Investigator# 24891 | Houston | Texas | 77030 | — |
| Site Reference ID/Investigator# 23382 | San Antonio | Texas | 78215 | — |
| Site Reference ID/Investigator# 24715 | Salt Lake City | Utah | 84132-2410 | — |
| Site Reference ID/Investigator# 25463 | Seattle | Washington | 98101 | — |
| Site Reference ID/Investigator# 23383 | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01074008, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 7, 2015 · Synced May 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01074008 live on ClinicalTrials.gov.