Ixabepilone + Carboplatin Metastatic Breast Cancer
Public ClinicalTrials.gov record NCT01075100. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase II Trial of Ixabepilone Plus Carboplatin in Patients With Metastatic Breast Cancer: The ECLIPSE Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Ixabepilone adds significantly to the antitumor effectiveness of capecitabine in both ER+ and triple negative breast cancer. Ixabepilone has substantial antitumor activity in taxane-refractory patients and novel combinations are needed in this poor prognosis population. Carboplatin in combination with gemcitabine or paclitaxel has activity in metastatic breast cancer (MBC); there is also demonstrated activity of the gemcitabine/carboplatin combination in the ER+ versus triple negative subsets. A Phase I study of ixabepilone plus carboplatin in solid tumor patients demonstrated the safety of this combination at the doses and schedule proposed for this Phase II trial (BMS data on file).
Study identification
- NCT ID
- NCT01075100
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 103 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2010 (Type not available)
- Primary completion
- Jun 2013 (Actual)
- Completion
- Jun 2013 (Actual)
- Last update posted
- Dec 7, 2016
2010 – 2013
United States locations
- U.S. sites
- 59
- U.S. states
- 21
- U.S. cities
- 53
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Hematology Oncology Associates | Phoenix | Arizona | 85012 | — |
| Arizona Oncology Associates, PC - NAHOA | Sedona | Arizona | 86336 | — |
| Arizona Oncology Associates, PC - HOPE | Tucson | Arizona | 85704 | — |
| Southwest Cancer care | Murrieta | California | 92562 | — |
| Rocky Mountain Cancer Centers | Denver | Colorado | 80220 | — |
| Florida Cancer Institute - New Hope | Hudson | Florida | 34667 | — |
| Melbourne Internal Medicine Associates | Melbourne | Florida | 32901 | — |
| Florida Institute of Research, Medicine & Surgery | Ocoee | Florida | 34761 | — |
| Cancer Care & Hematology Specialists of Chicagoland | Niles | Illinois | 60714 | — |
| Central Indiana Cancer Centers | Carmel | Indiana | 46032 | — |
| Alliance Hematology Oncology, P.A. | Westminster | Maryland | 21157 | — |
| Minnesota Oncology Hematology, P.A. | Minneapolis | Minnesota | 55404 | — |
| Maryland Oncology Hematology, PA The Medical Pavillion at Howard County | Columbia | Missouri | 21044 | — |
| Missouri Cancer Associates | Columbia | Missouri | 65201 | — |
| Kansas City Cancer Center, LLC | Kansas City | Missouri | 64131 | — |
| St. Joseph Oncology, Inc. | Saint Joseph | Missouri | 64507 | — |
| Comprehensive Cancer Care Centers of Nevada | Henderson | Nevada | 89074 | — |
| Hematology-Oncology Associates of Northern NJ, PA Carol G. Simon Cancer Center | Morristown | New Jersey | 07962 | — |
| Ruth Oratz MD | New York | New York | 10016 | — |
| Interlakes Oncology & Hematology, P.C | Rochester | New York | 14623 | — |
| Raleigh Hematology Oncology Associates | Raleigh | North Carolina | 27607 | — |
| Dayton Oncology & Hematology, P.A. Greater Dayton Cancer Center | Kettering | Ohio | 45409 | — |
| Northwest Cancer Specialists, PC | Portland | Oregon | 97213 | — |
| Medical Oncology Associates of Wyoming Valley, PC | Kingston | Pennsylvania | 18704 | — |
| Cancer Centers of the Carolinas | Greenville | South Carolina | 29605 | — |
| Texas Oncology - Abilene | Abilene | Texas | 79606 | — |
| Texas Oncology - Amarillo | Amarillo | Texas | 79106 | — |
| Texas Oncology - Austin Midtown | Austin | Texas | 78705 | — |
| Texas Oncology - Bedford | Bedford | Texas | 76022 | — |
| Texas Oncology Medical City Dallas | Dallas | Texas | 75230 | — |
| Texas Oncology-Dallas Presbyterian Hospital | Dallas | Texas | 75231 | — |
| Texas Oncology-Methodist Charlton Cancer Center | Dallas | Texas | 75237 | — |
| Texas Oncology | Dallas | Texas | 75246 | — |
| Texas Oncology- Denton South | Denton | Texas | 76210 | — |
| Texas Oncology-Fort Worth 12 Ave | Fort Worth | Texas | 76104 | — |
| Texas Oncology-Memorial City | Houston | Texas | 77024 | — |
| Texas Oncology- Lewisville | Lewisville | Texas | 75067 | — |
| Texas Oncology-Longview Cancer Center | Longview | Texas | 75601 | — |
| Texas Oncology-McAllen South Second Street | McAllen | Texas | 78509 | — |
| Texas Oncology-Mesquite | Mesquite | Texas | 75150 | — |
| Texas Oncology-Midland Allison Cancer Center | Midland | Texas | 79701 | — |
| Texas Oncology- Odessa West Texas Cancer Center | Odessa | Texas | 79761 | — |
| Paris Regional Cancer Center | Paris | Texas | 75460 | — |
| Cancer Care Centers of South Texas | San Antonio | Texas | 78217 | — |
| Cancer Care Centers of South Texas-HOAST | San Antonio | Texas | 78229 | — |
| Texas Cancer Center - Sherman | Sherman | Texas | 75090 | — |
| Texas Oncology - Sugar Land | Sugar Land | Texas | 77479 | — |
| Texas Oncology-Tyler | Tyler | Texas | 75702 | — |
| Texas Oncology-Waco | Waco | Texas | 76712 | — |
| Texas Oncology Wichita Falls Texoma Cancer Center | Wichita Falls | Texas | 76310 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Highline Medical Oncology | Burien | Washington | 98166 | — |
| Puget Sound Cancer Centers | Edmonds | Washington | 98026 | — |
| Columbia Basin Hematology & Oncology | Kennewick | Washington | 99336 | — |
| Puget Sound Cancer Centers | Seattle | Washington | 98133 | — |
| Cancer Care Northwest | Spokane | Washington | 99202 | — |
| Evergreen Hematology & Oncology | Spokane | Washington | 99218 | — |
| Yakima Valley Memorial Hospital/North Star Lodge | Yakima | Washington | 98902 | — |
| Raleigh Regional Cancer Center dba Beckley Oncology Associates Inc. | Beckley | West Virginia | 25801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01075100, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 7, 2016 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01075100 live on ClinicalTrials.gov.