Effect of Otamixaban Versus Unfractionated Heparin + Eptifibatide in Patients With Unstable Angina/Non ST Elevation Myocardial Infarction Undergoing Early Invasive Strategy
Public ClinicalTrials.gov record NCT01076764. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Double-blind, Triple-dummy Trial to Compare the Efficacy of Otamixaban With Unfractionated Heparin + Eptifibatide, in Patients With Unstable Angina/Non ST Segment Elevation Myocardial Infarction Scheduled to Undergo an Early Invasive Strategy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Primary Objective: * To demonstrate the superior efficacy (composite of all-cause death + Myocardial Infarction (MI)) of Otamixaban to Unfractionated Heparin (UFH) + Eptifibatide Secondary Objectives: * To demonstrate the superior efficacy (composite of all-cause death + MI + any stroke) of Otamixaban as compared to UFH + Eptifibatide * To document the effect of Otamixaban on rehospitalization or prolongation of hospitalization due to a new episode of myocardial ischemia/myocardial infarction as compared to UFH + eptifibatide * To document the effect on mortality (all cause death) of Otamixaban as compared to UFH + eptifibatide * To document the safety of Otamixaban as compared to UFH + eptifibatide * To document the effect of Otamixaban on thrombotic procedural complications during the index Percutaneous Coronary Intervention (PCI) as compared to UFH + eptifibatide
Study identification
- NCT ID
- NCT01076764
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 13,220 participants
Conditions and interventions
Conditions
Interventions
- Otamixaban Drug
- Placebo (for Otamixaban) Drug
- UFH Drug
- Placebo (for UFH) Drug
- Eptifibatide Drug
- Placebo (for Eptifibatide) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2010 (Type not available)
- Primary completion
- May 2013 (Actual)
- Completion
- May 2013 (Actual)
- Last update posted
- May 4, 2016
2010 – 2013
United States locations
- U.S. sites
- 107
- U.S. states
- 34
- U.S. cities
- 85
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigational Site Number 840015 | Huntsville | Alabama | 35801 | — |
| Investigational Site Number 840569 | Phoenix | Arizona | 85008 | — |
| Investigational Site Number 840703 | Phoenix | Arizona | 85054 | — |
| Investigational Site Number 840101 | Anaheim | California | 92801 | — |
| Investigational Site Number 840151 | Anaheim | California | 92801 | — |
| Investigational Site Number 840213 | Beverly Hills | California | 90211 | — |
| Investigational Site Number 840572 | Huntington Beach | California | 92648 | — |
| Investigational Site Number 840201 | Long Beach | California | 90806 | — |
| Investigational Site Number 840071 | Los Angeles | California | 90024 | — |
| Investigational Site Number 840557 | Los Angeles | California | 90024 | — |
| Investigational Site Number 840903 | Northridge | California | 91328 | — |
| Investigational Site Number 840065 | San Francisco | California | 94143 | — |
| Investigational Site Number 840561 | Santa Rosa | California | 95405 | — |
| Investigational Site Number 840721 | Littleton | Colorado | 80120 | — |
| Investigational Site Number 840551 | Bridgeport | Connecticut | 06606 | — |
| Investigational Site Number 840166 | New Haven | Connecticut | 06511 | — |
| Investigational Site Number 840520 | Washington D.C. | District of Columbia | 20010 | — |
| Investigational Site Number 840185 | Fort Lauderdale | Florida | 33322 | — |
| Investigational Site Number 840028 | Jacksonville | Florida | 32204 | — |
| Investigational Site Number 840047 | Lake Mary | Florida | 32746 | — |
| Investigational Site Number 840500 | Melbourne | Florida | 32901 | — |
| Investigational Site Number 840706 | Miami | Florida | 33133 | — |
| Investigational Site Number 840009 | Ocala | Florida | 34471 | — |
| Investigational Site Number 840146 | Ocala | Florida | 34471 | — |
| Investigational Site Number 840577 | Orlando | Florida | 32803 | — |
| Investigational Site Number 840021 | Sarasota | Florida | 34239 | — |
| Investigational Site Number 840902 | St. Petersburg | Florida | 33701 | — |
| Investigational Site Number 840508 | Tampa | Florida | 33613 | — |
| Investigational Site Number 840719 | Gainesville | Georgia | 30501 | — |
| Investigational Site Number 840532 | Boise | Idaho | 83712 | — |
| Investigational Site Number 840105 | Aurora | Illinois | 60506 | — |
| Investigational Site Number 840190 | Chicago | Illinois | 60612 | — |
| Investigational Site Number 840205 | Chicago | Illinois | 60637 | — |
| Investigational Site Number 840521 | Harvey | Illinois | 60426 | — |
| Investigational Site Number 840148 | Joliet | Illinois | 60435 | — |
| Investigational Site Number 840042 | Hammond | Indiana | 46320 | — |
| Investigational Site Number 840554 | Indianapolis | Indiana | 46202 | — |
| Investigational Site Number 840560 | Muncie | Indiana | 47303-3400 | — |
| Investigational Site Number 840904 | Ames | Iowa | 50010 | — |
| Investigational Site Number 840058 | West Des Moines | Iowa | 50266 | — |
| Investigational Site Number 840912 | Overland | Kansas | 66209 | — |
| Investigational Site Number 840568 | Louisville | Kentucky | 40207 | — |
| Investigational Site Number 840534 | Alexandria | Louisiana | 71301 | — |
| Investigational Site Number 840564 | Lake Charles | Louisiana | 70601 | — |
| Investigational Site Number 840533 | New Orleans | Louisiana | 70112 | — |
| Investigational Site Number 840517 | Dearborn | Michigan | 48123 | — |
| Investigational Site Number 840544 | Kalamazoo | Michigan | 49007 | — |
| Investigational Site Number 840531 | Saginaw | Michigan | 48602 | — |
| Investigational Site Number 840525 | Minneapolis | Minnesota | 55404 | — |
| Investigational Site Number 840510 | Minneapolis | Minnesota | 55433 | — |
| Investigational Site Number 840527 | Tupelo | Mississippi | 38801 | — |
| Investigational Site Number 840208 | Bridgeton | Missouri | 63044 | — |
| Investigational Site Number 840209 | Independence | Missouri | 64057 | — |
| Investigational Site Number 840194 | Kansas City | Missouri | 64108 | — |
| Investigational Site Number 840138 | Kansas City | Missouri | 64114 | — |
| Investigational Site Number 840056 | Kansas City | Missouri | 64128 | — |
| Investigational Site Number 840210 | St Louis | Missouri | 63128 | — |
| Investigational Site Number 840530 | St Louis | Missouri | 63128 | — |
| Investigational Site Number 840580 | St Louis | Missouri | 63128 | — |
| Investigational Site Number 840052 | St Louis | Missouri | 63131 | — |
| Investigational Site Number 840529 | Kalispell | Montana | 59901 | — |
| Investigational Site Number 840059 | Omaha | Nebraska | 68122 | — |
| Investigational Site Number 840727 | Omaha | Nebraska | 68122 | — |
| Investigational Site Number 840079 | Omaha | Nebraska | 68131 | — |
| Investigational Site Number 840157 | Reno | Nevada | 89502 | — |
| Investigational Site Number 840518 | Brooklyn | New York | 11215 | — |
| Investigational Site Number 840539 | New York | New York | 10021 | — |
| Investigational Site Number 840585 | Charlotte | North Carolina | 28204 | — |
| Investigational Site Number 840515 | Greenville | North Carolina | 27834 | — |
| Investigational Site Number 840566 | Raleigh | North Carolina | 27610 | — |
| Investigational Site Number 840908 | Winston-Salem | North Carolina | 27157-1071 | — |
| Investigational Site Number 840136 | Minot | North Dakota | 58701 | — |
| Investigational Site Number 840082 | Toledo | Ohio | 43608 | — |
| Investigational Site Number 840025 | Midwest City | Oklahoma | 73110 | — |
| Investigational Site Number 840049 | Oklahoma City | Oklahoma | 73112 | — |
| Investigational Site Number 840905 | Oklahoma City | Oklahoma | 73112 | — |
| Investigational Site Number 840193 | Oklahoma City | Oklahoma | 73135 | — |
| Investigational Site Number 840901 | Tulsa | Oklahoma | 74104 | — |
| Investigational Site Number 840206 | Eugene | Oregon | 97401 | — |
| Investigational Site Number 840540 | Chambersburg | Pennsylvania | 17201 | — |
| Investigational Site Number 840519 | Doylestown | Pennsylvania | 18901 | — |
| Investigational Site Number 840003 | Erie | Pennsylvania | 16502-4604 | — |
| Investigational Site Number 840098 | Harrisburg | Pennsylvania | 17110 | — |
| Investigational Site Number 840573 | Philadelphia | Pennsylvania | 19104 | — |
| Investigational Site Number 840075 | Pittsburgh | Pennsylvania | 15224 | — |
| Investigational Site Number 840911 | Pittsburgh | Pennsylvania | 15240 | — |
| Investigational Site Number 840211 | Washington | Pennsylvania | 15301 | — |
| Investigational Site Number 840072 | Oak Ridge | Tennessee | 37830 | — |
| Investigational Site Number 840023 | Amarillo | Texas | 79106 | — |
| Investigational Site Number 840203 | Austin | Texas | 78745 | — |
| Investigational Site Number 840574 | Austin | Texas | 78758 | — |
| Investigational Site Number 840060 | Dallas | Texas | 75216 | — |
| Investigational Site Number 840578 | Dallas | Texas | — | — |
| Investigational Site Number 840715 | Fort Worth | Texas | 76104 | — |
| Investigational Site Number 840090 | Houston | Texas | 77030 | — |
| Investigational Site Number 840207 | Houston | Texas | 77030 | — |
| Investigational Site Number 840559 | Houston | Texas | 77096 | — |
| Investigational Site Number 840586 | Houston | Texas | 77096 | — |
| Investigational Site Number 840087 | Tyler | Texas | 75701 | — |
| Investigational Site Number 840910 | Victoria | Texas | 77901 | — |
| Investigational Site Number 840555 | Wichita Falls | Texas | 76310 | — |
| Investigational Site Number 840553 | Richmond | Virginia | 23249 | — |
| Investigational Site Number 840188 | Richmond | Virginia | 23298 | — |
| Investigational Site Number 840165 | Salem | Virginia | 24153 | — |
| Investigational Site Number 840565 | Winchester | Virginia | 22601 | — |
| Investigational Site Number 840121 | Tacoma | Washington | 98405 | — |
| Investigational Site Number 840513 | Manitowoc | Wisconsin | 54220 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 500 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01076764, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2016 · Synced Oct 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01076764 live on ClinicalTrials.gov.