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Completed Phase 3 Interventional Results available

Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Relapsed Multiple Myeloma

ClinicalTrials.gov ID: NCT01080391

Public ClinicalTrials.gov record NCT01080391. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 13, 2026, 6:44 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Multicenter, Phase 3 Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Relapsed Multiple Myeloma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective was to compare progression-free survival in adults with relapsed multiple myeloma who are receiving CRd vs participants receiving Rd in a randomized multicenter setting.

Study identification

NCT ID
NCT01080391
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Amgen
Industry
Enrollment
792 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 14, 2010 (Actual)
Primary completion
Jun 16, 2014 (Actual)
Completion
Dec 5, 2017 (Actual)
Last update posted
Sep 21, 2022

2010 – 2017

United States locations

U.S. sites
22
U.S. states
15
U.S. cities
20
Facility City State ZIP Site status
Mayo Clinic Scottsdale Arizona 85259 —
Providence St. Joseph Medical Center Burbank California 91505 —
St. Jude Hospital Yorba Linda dba; St. Joseph Heritage Healthcare Santa Rosa California 94503 —
Stanford University Stanford California 94305 —
Colorado Blood Cancer Institute Denver Colorado 80218 —
Cancer and Blood Disease Center Lecanto Florida 34461 —
Rush University Medical Center Chicago Illinois 60612 —
Indiana University Health Melvin and Bren Simon Cancer Center Indianapolis Indiana 46202 —
University of Kansas Cancer Center Kansas City Kansas 66160 —
The University of Michigan - Comprehensive Cancer Center Ann Arbor Michigan 48109 —
Mayo Clinic Rochester Minnesota 55905 —
John Theurer Cancer Center at Hackensack University Medical Center Hackensack New Jersey 07601 —
NYU Clinical Cancer Center New York New York 10016 —
Weill Cornell Medical College New York New York 10021 —
Associates in Oncology and Hematology Chattanooga Tennessee 37404 —
The Don & Sybil Harrington Cancer Center Amarillo Texas 79106 —
Baylor Sammons Cancer Center Dallas Texas 75246 —
UT Southwestern Medical Center at Dallas Dallas Texas 75390-8565 —
The University of Texas, MD Anderson Cancer Center Houston Texas 77030 —
Scott and White Memorial Hospital Temple Texas 76508 —
Fred Hutchinson Cancer Research Center Seattle Washington 98109 —
Froedtert & Medical College of Wisconsin Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 105 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01080391, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 21, 2022 · Synced Oct 13, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01080391 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →