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Completed Phase 2 Interventional Results available

PF-00489791 For The Treatment Of Raynaud's

ClinicalTrials.gov ID: NCT01090492

Public ClinicalTrials.gov record NCT01090492. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 11:29 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2a Randomized Double-blinded, Placebo And Active Controlled Two Cohort Two Doses Cross-over Multi-center Clinical Study To Assess Efficacy Of A Once Daily Administration Of A Phosphodiesterase 5 Inhibitor (Pf-00489791) For The Treatment Of Vasospasm In Primary And Secondary Raynaud's Phenomenon

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The investigators propose that once daily administration of PF-00489791, a phosphodiesterase inhibitor, will reduce vasospasm and improve symptoms and signs associated with Primary and Secondary Raynaud's Phenomenon.

Study identification

NCT ID
NCT01090492
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Pfizer
Industry
Enrollment
243 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 4, 2010 (Actual)
Primary completion
May 31, 2011 (Actual)
Completion
May 31, 2011 (Actual)
Last update posted
May 16, 2018

2010 – 2011

United States locations

U.S. sites
23
U.S. states
15
U.S. cities
22
Facility City State ZIP Site status
Stanford Hospital and Outpatient Center Redwood City California 94063 —
University of Connecticut Health Center Farmington Connecticut 06030-5353 —
Georgetown University Hospital Washington D.C. District of Columbia 20007 —
Arthritis and Rheumatology of Georgia Atlanta Georgia 30342 —
Rockford Orthopedic Associates Rockford Illinois 61107 —
Diagnostic Rheumatology and Research, PC Indianapolis Indiana 46227 —
Memorial Health System, Inc. dba Memorial Medical Group Clinical Research Institute South Bend Indiana 46601 —
Johns Hopkins University - Division of Rheumatology Baltimore Maryland 21224 —
The Center for Rheumatology and Bone Research Wheaton Maryland 20902 —
Clinical Pharmacology Study Group Worcester Massachusetts 01610 —
University of Michigan Ann Arbor Michigan 48106 —
University of Michigan Health System Ann Arbor Michigan 48109 —
West Michigan Rheumatology, PLLC Grand Rapids Michigan 49546 —
Physician Research Collaboration, LLC Lincoln Nebraska 68516 —
UMDNJ - Robert Wood Johnson Medical Center Clinical Research Center New Brunswick New Jersey 08903-0019 —
The Center for Rheumatology Albany New York 12206 —
Regional Rheumatology Associates Binghamton New York 13905 —
AAIR Research Center Rochester New York 14618 —
East Penn Rheumatology Associates, PC Bethlehem Pennsylvania 18015 —
Altoona Center for Clinical Research Duncansville Pennsylvania 16635 —
Rheumatic Disease Associates, Ltd. Willow Grove Pennsylvania 19090 —
Metroplex Clinical Research Center Dallas Texas 75231 —
Rainier Clinical Research Center, Inc. Renton Washington 98057 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01090492, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 16, 2018 · Synced Oct 20, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01090492 live on ClinicalTrials.gov.

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