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Terminated Phase 2 Interventional Results available

A Study Of The Efficacy And Safety Of CP-601,927 Augmentation Of Antidepressant Therapy In Major Depression

ClinicalTrials.gov ID: NCT01098240

Public ClinicalTrials.gov record NCT01098240. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 4:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A RANDOMIZED PHASE 2A, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF THE EFFICACY AND SAFETY OF CP-601,927 AUGMENTATION OF ANTIDEPRESSANT THERAPY IN MAJOR DEPRESSION

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objectives of this study are to: 1) Evaluate the efficacy of CP 601,927 compared to placebo in the augmentation of antidepressant therapy (ADT) in patients with Major Depressive Disorder (MDD) using the Montgomery Asberg Depression Rating Scale (MADRS). 2) Evaluate the safety and tolerability of CP 601,927 in patients with MDD on ADT.

Study identification

NCT ID
NCT01098240
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Pfizer
Industry
Enrollment
297 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 13, 2010
Primary completion
Sep 11, 2011
Completion
Sep 11, 2011
Last update posted
May 2, 2021

2010 – 2011

United States locations

U.S. sites
58
U.S. states
25
U.S. cities
47
Facility City State ZIP Site status
Arkansas Psychiatric Clinic Clinical Research Trials, P.A. Little Rock Arkansas 72223
Southwestern Research Incorporated Beverly Hills California 90210
Collaborative Neuroscience Network, Inc. Garden Grove California 92845
Synergy Clinical Research Center National City California 91950
Artemis Institute for Clinical Research San Diego California 92123
Radiant Research, Inc. Denver Colorado 80239
Comprehensive Psychiatric Care Norwich Connecticut 06360
William B. Backus Hospital Satellite Blood Draw Norwich Connecticut 06360
Clinical Neuroscience Solutions, Inc. Jacksonville Florida 32216
Florida Clinical Research Center, LLC Maitland Florida 32751
Clinical Neuroscience Solutions, Inc. Orlando Florida 32806
Comprehensive NeuroScience, Inc. St. Petersburg Florida 33716
Atlanta Center for Medical Research Atlanta Georgia 30308
Atlanta Institute of Medicine and Research Atlanta Georgia 30328
AMR-Baber Research Inc. Naperville Illinois 60563
Psychiatric Medicine Associates, LLC. Skokie Illinois 60076
Goldpoint Clinical Research, LLC Indianapolis Indiana 46260
Clinco Terre Haute Indiana 47802
Heartland Research Associates, LLC Wichita Kansas 67207
Lake Charles Clinical Trials Lake Charles Louisiana 70629
Louisiana Research Associates, Inc. New Orleans Louisiana 70114
Louisiana Clinical Research, LLC Shreveport Louisiana 71115
Massachusetts General Hospital Boston Massachusetts 02171
AccelRx Research Fall River Massachusetts 02721
Detroit Bio-Medical Laboratories, Inc. Rochester Hills Michigan 48307
Rochester Center for Behavioral Medicine Rochester Hills Michigan 48307
St. Charles Psychiatric Associates - Midwest Research Group Saint Charles Missouri 63301
Center for Emotional Fitness Cherry Hill New Jersey 08002
Social Psychiatry Research Institute Brooklyn New York 11235
Erie County Medical Center / State University of New York at Buffalo affiliate Buffalo New York 14215
Comprehensive NeuroScience, Inc. Fresh Meadows New York 11366
Montefiore Medical Center The Bronx New York 10467
Midwest Clinical Research Center Dayton Ohio 45417
Kettlie Joseph Daniels, MD, Inc. Toledo Ohio 43609
Neurology and Neuroscience Center of Ohio Toledo Ohio 43623
IPS Research Oklahoma City Oklahoma 73103
Cutting Edge Research Group Oklahoma City Oklahoma 73116
Summit Research Network (Oregon), Inc. Portland Oregon 97210
Lehigh Valley Health Network Allentown Pennsylvania 18103
City Line Family Medicine Bala-Cynwyd Pennsylvania 19004
Suburban Research Associates Media Pennsylvania 19063
University of Pennsylvania / Department of Psychiatry Philadelphia Pennsylvania 19104
Frankford Avenue Family Practice, PC Philadelphia Pennsylvania 19136
Lincoln Research Lincoln Rhode Island 02865
Carolina Clinical Research Service LLC Columbia South Carolina 29201
FutureSearch Trials Austin Texas 78731
FutureSearch Trials of Dallas, L.P. Dallas Texas 75231
University of Texas (UT) Southwestern Medical Center at Dallas Dallas Texas 75235
University of Texas (UT) Southwestern Medical Center at Dallas Dallas Texas 75390-9119
InSite Clinical Research DeSoto Texas 75115
Radiant Research, Inc Salt Lake City Utah 84107
University of Utah School of Medicine Department of Psychiatry Mood Disorders Clinic Salt Lake City Utah 84132
University of Virginia Health System / Department of Psychiatry and Neurobehavioral Sciences Charlottesville Virginia 22903
Mcguire Hall Annex Richmond Virginia 23219
Nelson Clinic Richmond Virginia 23219
Virginia Commonwealth University (VCU) Medical Center Richmond Virginia 23298-0155
Northbrooke Research Center Brown Deer Wisconsin 53223
Dean Foundation for Health, Research and Education Middleton Wisconsin 53562

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01098240, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 2, 2021 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01098240 live on ClinicalTrials.gov.

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