ClinicalTrials.gov record
Cardiovascular Safety of Febuxostat and Allopurinol in Participants With Gout and Cardiovascular Comorbidities (CARES)
ClinicalTrials.gov ID: NCT01101035
Public ClinicalTrials.gov record NCT01101035. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Active-Control, Phase 3B Study to Evaluate the Cardiovascular Safety of Febuxostat and Allopurinol in Subjects With Gout and Cardiovascular Comorbidities
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to see whether subjects with gout who receive febuxostat or allopurinol for up to 9 years have a higher rate of serious heart and blood vessel complications (major cardiovascular events).
Study identification
- NCT ID
- NCT01101035
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 6,198 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 23, 2010 (Actual)
- Primary completion
- May 15, 2017 (Actual)
- Completion
- Jul 18, 2017 (Actual)
- Last update posted
- Jun 14, 2018
2010 – 2017
United States locations
- U.S. sites
- 202
- U.S. states
- 37
- U.S. cities
- 202
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Decatur | Georgia | — | — |
| Not listed | Dunwoody | Georgia | — | — |
| Not listed | Marietta | Georgia | — | — |
| Not listed | Norcross | Georgia | — | — |
| Not listed | Roswell | Georgia | — | — |
| Not listed | Suwanee | Georgia | — | — |
| Not listed | Waycross | Georgia | — | — |
| Not listed | Honolulu | Hawaii | — | — |
| Not listed | Boise | Idaho | — | — |
| Not listed | Coeur d'Alene | Idaho | — | — |
| Not listed | Nampa | Idaho | — | — |
| Not listed | Addison | Illinois | — | — |
| Not listed | Arlington Heights | Illinois | — | — |
| Not listed | Evanston | Illinois | — | — |
| Not listed | Evergreen Park | Illinois | — | — |
| Not listed | Flossmoor | Illinois | — | — |
| Not listed | Melrose Park | Illinois | — | — |
| Not listed | Morton | Illinois | — | — |
| Not listed | Naperville | Illinois | — | — |
| Not listed | Quincy | Illinois | — | — |
| Not listed | Rockford | Illinois | — | — |
| Not listed | Bloomington | Indiana | — | — |
| Not listed | Brownsburg | Indiana | — | — |
| Not listed | Lafayette | Indiana | — | — |
| Not listed | Valparaiso | Indiana | — | — |
| Not listed | Iowa City | Iowa | — | — |
| Not listed | Lenexa | Kansas | — | — |
| Not listed | Overland Park | Kansas | — | — |
| Not listed | Topeka | Kansas | — | — |
| Not listed | Wichita | Kansas | — | — |
| Not listed | Elizabethtown | Kentucky | — | — |
| Not listed | Lexington | Kentucky | — | — |
| Not listed | Owensboro | Kentucky | — | — |
| Not listed | Paducah | Kentucky | — | — |
| Not listed | Mer Rouge | Louisiana | — | — |
| Not listed | Monroe | Louisiana | — | — |
| Not listed | Shreveport | Louisiana | — | — |
| Not listed | Biddeford | Maine | — | — |
| Not listed | Rockport | Maine | — | — |
| Not listed | Baltimore | Maryland | — | — |
| Not listed | Cumberland | Maryland | — | — |
| Not listed | Hagerstown | Maryland | — | — |
| Not listed | Lutherville | Maryland | — | — |
| Not listed | Wheaton | Maryland | — | — |
| Not listed | Brockton | Massachusetts | — | — |
| Not listed | Fall River | Massachusetts | — | — |
| Not listed | Hyannis | Massachusetts | — | — |
| Not listed | Worcester | Massachusetts | — | — |
| Not listed | Ann Arbor | Michigan | — | — |
| Not listed | Bingham Farms | Michigan | — | — |
| Not listed | Chelsea | Michigan | — | — |
| Not listed | Detroit | Michigan | — | — |
| Not listed | Flint | Michigan | — | — |
| Not listed | Kalamazoo | Michigan | — | — |
| Not listed | Lansing | Michigan | — | — |
| Not listed | Chaska | Minnesota | — | — |
| Not listed | Duluth | Minnesota | — | — |
| Not listed | Edina | Minnesota | — | — |
| Not listed | Saint Paul | Minnesota | — | — |
| Not listed | Jackson | Mississippi | — | — |
| Not listed | Olive Branch | Mississippi | — | — |
| Not listed | Port Gibson | Mississippi | — | — |
| Not listed | Clarkson Valley | Missouri | — | — |
| Not listed | Hazelwood | Missouri | — | — |
| Not listed | Kansas City | Missouri | — | — |
| Not listed | Saint Charles | Missouri | — | — |
| Not listed | St Louis | Missouri | — | — |
| Not listed | Washington | Missouri | — | — |
| Not listed | Billings | Montana | — | — |
| Not listed | Butte | Montana | — | — |
| Not listed | Bellevue | Nebraska | — | — |
| Not listed | Grand Island | Nebraska | — | — |
| Not listed | Lincoln | Nebraska | — | — |
| Not listed | Omaha | Nebraska | — | — |
| Not listed | Henderson | Nevada | — | — |
| Not listed | Las Vegas | Nevada | — | — |
| Not listed | Reno | Nevada | — | — |
| Not listed | Brick | New Jersey | — | — |
| Not listed | Edison | New Jersey | — | — |
| Not listed | Oradell | New Jersey | — | — |
| Not listed | Albuquerque | New Mexico | — | — |
| Not listed | Las Vegas | New Mexico | — | — |
| Not listed | Endwell | New York | — | — |
| Not listed | Freeport | New York | — | — |
| Not listed | Glens Falls | New York | — | — |
| Not listed | Mineola | New York | — | — |
| Not listed | New Windsor | New York | — | — |
| Not listed | New York | New York | — | — |
| Not listed | Rochester | New York | — | — |
| Not listed | West Seneca | New York | — | — |
| Not listed | Westfield | New York | — | — |
| Not listed | Asheboro | North Carolina | — | — |
| Not listed | Cary | North Carolina | — | — |
| Not listed | Charlotte | North Carolina | — | — |
| Not listed | Columbia | North Carolina | — | — |
| Not listed | Greensboro | North Carolina | — | — |
| Not listed | Huntersville | North Carolina | — | — |
| Not listed | Lenoir | North Carolina | — | — |
| Not listed | Monroe | North Carolina | — | — |
| Not listed | Raleigh | North Carolina | — | — |
| Not listed | Salisbury | North Carolina | — | — |
| Not listed | Shelby | North Carolina | — | — |
| Not listed | Wilmington | North Carolina | — | — |
| Not listed | Winston-Salem | North Carolina | — | — |
| Not listed | Fargo | North Dakota | — | — |
| Not listed | Akron | Ohio | — | — |
| Not listed | Centerville | Ohio | — | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Columbus | Ohio | — | — |
| Not listed | Dayton | Ohio | — | — |
| Not listed | Delaware | Ohio | — | — |
| Not listed | Franklin | Ohio | — | — |
| Not listed | Kettering | Ohio | — | — |
| Not listed | Lyndhurst | Ohio | — | — |
| Not listed | Marion | Ohio | — | — |
| Not listed | Mentor | Ohio | — | — |
| Not listed | Middleburg Heights | Ohio | — | — |
| Not listed | Toledo | Ohio | — | — |
| Not listed | Willoughby Hills | Ohio | — | — |
| Not listed | Oklahoma City | Oklahoma | — | — |
| Not listed | Tulsa | Oklahoma | — | — |
| Not listed | Ashland | Oregon | — | — |
| Not listed | Bend | Oregon | — | — |
| Not listed | Eugene | Oregon | — | — |
| Not listed | Portland | Oregon | — | — |
| Not listed | Altoona | Pennsylvania | — | — |
| Not listed | Bensalem | Pennsylvania | — | — |
| Not listed | Bethlehem | Pennsylvania | — | — |
| Not listed | Downingtown | Pennsylvania | — | — |
| Not listed | Duncansville | Pennsylvania | — | — |
| Not listed | Ephrata | Pennsylvania | — | — |
| Not listed | Harleysville | Pennsylvania | — | — |
| Not listed | Lansdale | Pennsylvania | — | — |
| Not listed | McMurray | Pennsylvania | — | — |
| Not listed | Philadelphia | Pennsylvania | — | — |
| Not listed | Quakertown | Pennsylvania | — | — |
| Not listed | Wyomissing | Pennsylvania | — | — |
| Not listed | Cumberland | Rhode Island | — | — |
| Not listed | East Providence | Rhode Island | — | — |
| Not listed | Providence | Rhode Island | — | — |
| Not listed | Anderson | South Carolina | — | — |
| Not listed | Charleston | South Carolina | — | — |
| Not listed | Columbia | South Carolina | — | — |
| Not listed | Greenville | South Carolina | — | — |
| Not listed | Greenwood | South Carolina | — | — |
| Not listed | Greer | South Carolina | — | — |
| Not listed | Myrtle Beach | South Carolina | — | — |
| Not listed | Orangeburg | South Carolina | — | — |
| Not listed | Pelzer | South Carolina | — | — |
| Not listed | Simpsonville | South Carolina | — | — |
| Not listed | Spartanburg | South Carolina | — | — |
| Not listed | Athens | Tennessee | — | — |
| Not listed | Chattanooga | Tennessee | — | — |
| Not listed | Clarksville | Tennessee | — | — |
| Not listed | Collierville | Tennessee | — | — |
| Not listed | Fayetteville | Tennessee | — | — |
| Not listed | Jackson | Tennessee | — | — |
| Not listed | Kingsport | Tennessee | — | — |
| Not listed | Memphis | Tennessee | — | — |
| Not listed | New Tazewell | Tennessee | — | — |
| Not listed | Bellaire | Texas | — | — |
| Not listed | Carrollton | Texas | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | El Paso | Texas | — | — |
| Not listed | Fort Worth | Texas | — | — |
| Not listed | Grapevine | Texas | — | — |
| Not listed | Houston | Texas | — | — |
| Not listed | Irving | Texas | — | — |
| Not listed | McKinney | Texas | — | — |
| Not listed | New Braunfels | Texas | — | — |
| Not listed | Odessa | Texas | — | — |
| Not listed | Pearland | Texas | — | — |
| Not listed | Plano | Texas | — | — |
| Not listed | Richardson | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Southlake | Texas | — | — |
| Not listed | Sugar Land | Texas | — | — |
| Not listed | Tomball | Texas | — | — |
| Not listed | Waco | Texas | — | — |
| Not listed | Bountiful | Utah | — | — |
| Not listed | Draper | Utah | — | — |
| Not listed | Salt Lake City | Utah | — | — |
| Not listed | West Jordan | Utah | — | — |
| Not listed | Alexandria | Virginia | — | — |
| Not listed | Arlington | Virginia | — | — |
| Not listed | Burke | Virginia | — | — |
| Not listed | Danville | Virginia | — | — |
| Not listed | McLean | Virginia | — | — |
| Not listed | Norfolk | Virginia | — | — |
| Not listed | Richmond | Virginia | — | — |
| Not listed | Salem | Virginia | — | — |
| Not listed | Virginia Beach | Virginia | — | — |
| Not listed | Port Orchard | Washington | — | — |
| Not listed | Tacoma | Washington | — | — |
| Not listed | Clarksburg | West Virginia | — | — |
| Not listed | Green Bay | Wisconsin | — | — |
| Not listed | Milwaukee | Wisconsin | — | — |
| Not listed | New Berlin | Wisconsin | — | — |
| Not listed | Oregon | Wisconsin | — | — |
| Not listed | Verona | Wisconsin | — | — |
| Not listed | Waukesha | Wisconsin | — | — |
| Not listed | Weston | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01101035, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 14, 2018 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01101035 live on ClinicalTrials.gov.