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Completed Phase 2 Interventional

Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee

ClinicalTrials.gov ID: NCT01111045

Public ClinicalTrials.gov record NCT01111045. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 8, 2026, 10:06 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Double Blind, Randomized, Placebo-Controlled, Proof of Concept, Dose Finding Study of Intraarticular Bone Morphogenetic Protein (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The objectives of the study are to evaluate the safety and efficacy of intraarticular BMP-7 for the treatment of osteoarthritis of the knee.

Study identification

NCT ID
NCT01111045
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Stryker Biotech
Industry
Enrollment
355 participants

Conditions and interventions

Eligibility (public fields only)

Age range
40 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2010
Primary completion
Jul 31, 2011
Completion
Jul 31, 2011
Last update posted
Jan 31, 2012

2010 – 2011

United States locations

U.S. sites
25
U.S. states
12
U.S. cities
23
Facility City State ZIP Site status
Arizona Arthritis and Rheumatology Research Glendale Arizona 85304
University of Arizona Arthritis Center Tucson Arizona 85724
Stanford University School of Medicine Palo Alto California 94304
UC Davis Medical Center, Center for Aging Sacramento California 95817
Robin Dore, MD, Inc Tustin California 92780
Boulder Medical Center, PC Boulder Colorado 80304
Rheumatology Associates of S. Florida Boca Raton Florida 33486
The Arthritis Center Palm Harbor Florida 34684
Rheumatology Associates Stuart Florida 34996
Northwestern Center for Clinical Research Chicago Illinois 60611
Apex Medical Research, AMR, Inc Chicago Illinois 60616
Illinois Bone and Joint Institute Morton Grove Illinois 60053
Johns Hopkins Medical Center Baltimore Maryland 21224
Klein & Associates, MD, PA Cumberland Maryland 21502
Arthritis and Osteoporosis Center of Maryland Frederick Maryland 21702
The Center for Pharmaceutical Research, PC Kansas City Missouri 64114
Billings Clinic Billings Montana 59101
The Ohio State University Medical Center Columbus Ohio 43210
David R. Mandel, MD, Inc. Mayfield Village Ohio 44143
Altoona Center for Clinical Research Duncansville Pennsylvania 16635
Clinical Research Center of Reading West Reading Pennsylvania 19611
Baylor Research Institute Dallas Texas 75231
Houston Institute for Clinical Research Houston Texas 77074
Houston Medical Research Associates Houston Texas 77090
Tacoma Center for Arthritis Research Tacoma Washington 98405

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01111045, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 31, 2012 · Synced Sep 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01111045 live on ClinicalTrials.gov.

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