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Completed Phase 3 Interventional Results available

ACT-293987 in Pulmonary Arterial Hypertension

ClinicalTrials.gov ID: NCT01112306

Public ClinicalTrials.gov record NCT01112306. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:22 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Long-term Single-arm Open-label Study, to Assess the Safety and Tolerability of ACT-293987 in Patients With Pulmonary Arterial Hypertension

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Long-term, single-arm, multicenter, open-label extension, Phase 3 study, to evaluate the safety and tolerability of ACT-293987 in patients with PAH who participated in the double-blind study AC-065A302 (GRIPHON)

Study identification

NCT ID
NCT01112306
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Actelion
Industry
Enrollment
709 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 6, 2010
Primary completion
Aug 25, 2021
Completion
Aug 25, 2021
Last update posted
Mar 29, 2025

2010 – 2021

United States locations

U.S. sites
45
U.S. states
25
U.S. cities
45
Facility City State ZIP Site status
Not listed Mobile Alabama
Not listed Phoenix Arizona
Not listed Tucson Arizona
Not listed La Jolla California
Not listed Los Angeles California
Not listed Sacramento California
Not listed Torrance California
Not listed Newark Delaware
Not listed Atlanta Georgia
Not listed Augusta Georgia
Not listed Austell Georgia
Not listed Carmel Indiana
Not listed Iowa City Iowa
Not listed Kansas City Kansas
Not listed Louisville Kentucky
Not listed New Orleans Louisiana
Not listed Baltimore Maryland
Not listed Boston Massachusetts
Not listed Ann Arbor Michigan
Not listed Detroit Michigan
Not listed Troy Michigan
Not listed Rochester Minnesota
Not listed Chesterfield Missouri
Not listed St Louis Missouri
Not listed Newark New Jersey
Not listed Islandia New York
Not listed New York New York
Not listed The Bronx New York
Not listed Durham North Carolina
Not listed Winston-Salem North Carolina
Not listed Cincinnati Ohio
Not listed Cleveland Ohio
Not listed Columbus Ohio
Not listed Bend Oregon
Not listed Portland Oregon
Not listed Doylestown Pennsylvania
Not listed Philadelphia Pennsylvania
Not listed York Pennsylvania
Not listed Nashville Tennessee
Not listed Dallas Texas
Not listed Houston Texas
Not listed Norfolk Virginia
Not listed Richmond Virginia
Not listed Madison Wisconsin
Not listed Milwaukee Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 112 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01112306, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 29, 2025 · Synced Sep 2, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01112306 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →