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Completed Phase 3 Interventional

Apitox, Honeybee Toxin for Pain and Inflammation of Osteoarthritis

ClinicalTrials.gov ID: NCT01112722

Public ClinicalTrials.gov record NCT01112722. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 4:00 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double Blind, Active Controlled, Parallel Group, Clinical Study, to Evaluate the Safety and Efficacy of Apitox vs Histamine in Subjects With Refractory Osteoarthritis Pain and Inflammation of the Knee

Study identification

NCT ID
NCT01112722
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Apimeds, Inc.
Industry
Enrollment
363 participants

Conditions and interventions

Interventions

  • Apitox, purified honeybee toxin, lyophilized in saline Biological
  • histamine Biological

Biological

Eligibility (public fields only)

Age range
30 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2013
Primary completion
Oct 31, 2016
Completion
Nov 30, 2016
Last update posted
Dec 12, 2016

2013 – 2016

United States locations

U.S. sites
15
U.S. states
9
U.S. cities
14
Facility City State ZIP Site status
Functional Research LLC Gulf Shores Alabama 36542
Tucson Orthopaedic Institute Tucson Arizona 87512
SC Clinical Research Inc. Garden Grove California 92844
Axis Clinical Trials Los Angeles California 90036
Westlake Medical Research Thousand Oaks California 91360
SC Clinical Research Inc. Upland California 91786
Schrock Orthopedics Research Fort Lauderdale Florida 33316
AppleMed Research Inc. Miami Florida 33155
Radiant Research Inc. Pinellas Park Florida 33781
Beacon Clinical Brockton Massachusetts 02301
Radiant Research Inc Columbus Columbus Ohio 43212
Hillcrest Clinical Research Olahoma City Oklahoma 73119
PMG Research of Knoxville Knoxville Tennessee 37912
PMG Research of Knoxville Knoxville Tennessee 37938
Tekton Research Austin Texas 78745

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01112722, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 12, 2016 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01112722 live on ClinicalTrials.gov.

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