PRE-DETERMINE Cohort Study
Public ClinicalTrials.gov record NCT01114269. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
PRE-DETERMINE: Biologic Markers and MRI SCD Cohort Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a prospective, multi-center cohort study of patients with a history of coronary artery disease (CAD) and documentation of either a prior myocardial infarction (MI) or mild to moderate left ventricular dysfunction (LVEF 35-50%). The primary objective of this study is to determine whether biologic markers and ECGs can be utilized to advance SCD risk prediction in patients with CHD and LVEF\>30-35%. The overarching goal of the study is to identify a series of markers that alone or in combination specifically predict risk of arrhythmic death as compared to other causes of mortality among this at risk population of coronary heart disease (CHD) patients with preserved left ventricular ejection fraction (LVEF\> 30-35%). If biologic or ECG markers are identified that can specifically predict risk of ventricular arrhythmias, then these markers may serve as relatively inexpensive methods to identify those at risk. The public health impact of identifying markers could be quite substantial, leading to more efficient utilization of ICDs and advances in our understanding of mechanisms underlying SCD.
Study identification
- NCT ID
- NCT01114269
- Recruitment status
- Active, not recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 5,764 participants
Conditions and interventions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2007 (Actual)
- Primary completion
- Nov 2026 (Estimated)
- Completion
- Nov 2026 (Estimated)
- Last update posted
- Oct 7, 2025
2007 – 2026
United States locations
- U.S. sites
- 86
- U.S. states
- 33
- U.S. cities
- 79
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alaska Heart Institute | Anchorage | Alaska | 99508 | — |
| Phoenix Heart, PLLC | Glendale | Arizona | 85306 | — |
| Cardiovascular Consultants | Phoenix | Arizona | 85032 | — |
| Beaver Medical Group/Clinical Care Research | Banning | California | 92220 | — |
| Memorial Health System | Colorado Springs | Colorado | 80909 | — |
| Colorado Heart and Vascular | Denver | Colorado | 80204 | — |
| Bay Area Cardiology Associates, P.A. | Brandon | Florida | 33511 | — |
| University of Florida - Gainsville | Gainesville | Florida | 32610 | — |
| Reliable Clinical Research | Miami | Florida | 33135 | — |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Florida Hospital | Orlando | Florida | 32804 | — |
| Orlando Regional Medical Center | Orlando | Florida | 32806 | — |
| Palm Beach Gardens Research Center | Palm Beach Gardens | Florida | 33410 | — |
| Velella Research | Sarasota | Florida | 34233 | — |
| Tallahassee Research Institute, Inc. | Tallahassee | Florida | 32308 | — |
| Cardiology Associates of Palm Beach - West Palm Beach | West Palm Beach | Florida | 33401 | — |
| Georgia Heart Specialist | Covington | Georgia | 30014 | — |
| Northeast Georgia Heart Center, P.C. | Gainesville | Georgia | 30501 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Advocate Medical Group | Chicago | Illinois | 60643 | — |
| Advocate Medical Group - Heart and Vascular of IL | Chicago | Illinois | 60657 | — |
| Consultants in Cardiovascular Medicine | Melrose Park | Illinois | 60160 | — |
| Community Heart and Vascular | Anderson | Indiana | 46011 | — |
| Iowa Heart Center | West Des Moines | Iowa | 50266 | — |
| The University of Kansas | Kansas City | Kansas | 66160 | — |
| Baptist Health Lexington | Lexington | Kentucky | 40503 | — |
| Leonard J. Chabert Medical Center | Houma | Louisiana | 70363 | — |
| Maine Research Associates | Auburn | Maine | 04210 | — |
| Maine Research Associates - Lewiston | Lewiston | Maine | 04240 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Primary Care Cardiology Research | Ayer | Massachusetts | 01432 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| NECCR Internal Medicine and Cardiology Associates, LLC | Fall River | Massachusetts | 02720 | — |
| Hawthorn Medical Associates | North Dartmouth | Massachusetts | 02747 | — |
| Baystate Cardiology | Springfield | Massachusetts | 01199 | — |
| University of Michigan Medical Center | Ann Arbor | Michigan | 48109 | — |
| Oakwood Hospital & Medical Center | Dearborn | Michigan | 48124 | — |
| McLaren Medical Center - Macomb | Mount Clemens | Michigan | 48043 | — |
| Michigan Heart | Ypsilanti | Michigan | 48197 | — |
| Minneapolis VA Medical Center | Minneapolis | Minnesota | 55417 | — |
| University of Missouri Health Care | Columbia | Missouri | 65201 | — |
| Glacier View Cardiology | Kalispell | Montana | 59901 | — |
| The Cardiac Center of Creighton University | Omaha | Nebraska | 68131 | — |
| Advanced Heartcare, LLC | Bridgewater | New Jersey | 08807 | — |
| St. Joseph Regional Medical Center | Paterson | New Jersey | 07503 | — |
| New Mexico VA Healthcare Systems | Albuquerque | New Mexico | 87108 | — |
| Albany Associates Cardiology | Albany | New York | 12205 | — |
| Maimonides Medical Center | Brooklyn | New York | 11219 | — |
| Buffalo General Hospital/Kaleida Health | Buffalo | New York | 14203 | — |
| Jamaica Hospital Medical Center | Jamaica | New York | 11418 | — |
| Mid-Valley Cardiology | Kingston | New York | 12401 | — |
| Winthrop-University Hospital | Mineola | New York | 11501 | — |
| Gotham Cardiovascular | New York | New York | 10001 | — |
| Columbia University Health Center | New York | New York | 10032 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| St. Elizabeth Medical Center - Hotvedt | Utica | New York | 13501 | — |
| Asheville Cardiology Associates | Asheville | North Carolina | 28801 | — |
| Eastern Carolina Cardiovascular | Elizabeth City | North Carolina | 27909 | — |
| Northstate Clinical Research | Lenoir | North Carolina | 28645 | — |
| Pinehurst Medical Clinic, Inc. | Pinehurst | North Carolina | 28374 | — |
| Sanford Cardiology | Sanford | North Carolina | 27330 | — |
| Wake Forest | Winston-Salem | North Carolina | 27157 | — |
| Northeast Ohio Cardiovascular Specialists | Akron | Ohio | 44304 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| North Ohio Research, Ltd. | Elyria | Ohio | 44035 | — |
| Mercy Medical Associates | Fairfield | Ohio | 45014 | — |
| Northwest Ohio Cardiology Consultants/The Toledo Hospital | Toledo | Ohio | 43615 | — |
| Oklahoma City VA Medical Center Veterans Research and Education Foundation | Oklahoma City | Oklahoma | 73104 | — |
| Oklahoma Foundation for Cardiovascular Research | Oklahoma City | Oklahoma | 73120 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| St. Luke's Bethlehem | Bethlehem | Pennsylvania | 18018 | — |
| Doylestown Cardiology Associates | Doylestown | Pennsylvania | 18901 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| AnMed Health | Anderson | South Carolina | 29621 | — |
| VA Medical Center - Charleston | Charleston | South Carolina | 29425 | — |
| Carolina Cardiology Associates | Rock Hill | South Carolina | 29732 | — |
| Black Hills Cardiovascular Research | Rapid City | South Dakota | 57701 | — |
| Cardiovasular Research of Knoxville | Knoxville | Tennessee | 37917 | — |
| Memphis VA Medical Center | Memphis | Tennessee | 38104 | — |
| St. Luke's Episcopal Hospital | Houston | Texas | 77030 | — |
| Non-Invasive Cardiovascular PA | Houston | Texas | 77074 | — |
| Providence Health Center | Waco | Texas | 76712 | — |
| Intermountain Medical Center | Murray | Utah | 84157 | — |
| Cardiovascular Associates Virginia Beach | Virginia Beach | Virginia | 23454 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01114269, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 7, 2025 · Synced Oct 29, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01114269 live on ClinicalTrials.gov.