A Six-Month Randomized Controlled Trial (RCT) of Probuphine Safety and Efficacy in Opioid Addiction
Public ClinicalTrials.gov record NCT01114308. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Placebo and Active-Controlled, Multi-Center Study of Probuphine in Patients With Opioid Dependence
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Probuphine (buprenorphine implant) is an implant placed just below the skin containing buprenorphine (BPN). BPN is an approved treatment for opioid dependence. This study will confirm the efficacy of Probuphine vs. placebo and compare Probuphine treatment verses treatment with sublingual buprenorphine in the treatment of patients with opioid dependence.
Study identification
- NCT ID
- NCT01114308
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 287 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2010 (Type not available)
- Primary completion
- May 2011 (Actual)
- Completion
- May 2011 (Actual)
- Last update posted
- Dec 31, 2018
2010 – 2011
United States locations
- U.S. sites
- 20
- U.S. states
- 13
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| David Geffen School of Medicine at UCLA | Los Angeles | California | 90025 | — |
| Synergy Clinical Research Center | National City | California | 91950 | — |
| North County Clinical Research | Oceanside | California | 92056 | — |
| Friends Research Institute | Torrance | California | 90502 | — |
| Amit Vijapura, MD | Jacksonville | Florida | 32256 | — |
| Operation PAR, Inc. - TC Campus | Largo | Florida | 33771 | — |
| Fidelity Clinical Research, Inc. | Lauderhill | Florida | 33319 | — |
| Scientific Clinical Research, Inc. | North Miami | Florida | 33161 | — |
| BPRU, Behavioral Biology Research Center | Baltimore | Maryland | 21224 | — |
| SSTAR: Stanley Street Treatment and Resources, Inc. | Fall River | Massachusetts | 02720-6009 | — |
| Precise Research Centers | Flowood | Mississippi | 39232 | — |
| PsychCare Consultants Research | St Louis | Missouri | 63128 | — |
| New York VA Medical Center, NYU School of Medicine | New York | New York | 10010 | — |
| St. Luke's Roosevelt Hospital Center | New York | New York | 10025 | — |
| Duke University, Duke Addictions Program | Durham | North Carolina | 27705 | — |
| University of Cincinnati | Cincinnati | Ohio | 45220 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Carolina Clinical Trials, Inc. | Charleston | South Carolina | 29407 | — |
| University of Vermont | Burlington | Vermont | 05401 | — |
| Providence Behavioral Health Services | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01114308, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 31, 2018 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01114308 live on ClinicalTrials.gov.