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Completed Phase 3 Interventional Results available

Safety and Therapeutic Effects of Sapropterin Dihydrochloride on Neuropsychiatric Symptoms in Phenylketonuria (PKU) Patients

ClinicalTrials.gov ID: NCT01114737

Public ClinicalTrials.gov record NCT01114737. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 9:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-blind, Placebo-controlled, Randomized Study to Evaluate the Safety and Therapeutic Effects of Sapropterin Dihydrochloride on Neuropsychiatric Symptoms in Subjects With Phenylketonuria

Study identification

NCT ID
NCT01114737
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
BioMarin Pharmaceutical
Industry
Enrollment
206 participants

Conditions and interventions

Interventions

  • Sapropterin dihydrochloride Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
8 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2010
Primary completion
Feb 28, 2013
Completion
Feb 28, 2013
Last update posted
Jan 31, 2016

2010 – 2013

United States locations

U.S. sites
26
U.S. states
17
U.S. cities
26
Facility City State ZIP Site status
Not listed La Jolla California
Not listed Los Angeles California
Not listed Palo Alto California
Not listed San Francisco California
Not listed Aurora Colorado
Not listed Washington D.C. District of Columbia
Not listed Gainesville Florida
Not listed Tampa Florida
Not listed Atlanta Georgia
Not listed Chicago Illinois
Not listed Indianapolis Indiana
Not listed Boston Massachusetts
Not listed Minneapolis Minnesota
Not listed Albany New York
Not listed Buffalo New York
Not listed Rochester New York
Not listed Chapel Hill North Carolina
Not listed Cleveland Ohio
Not listed Portland Oregon
Not listed Hershey Pennsylvania
Not listed Philadelphia Pennsylvania
Not listed Pittsburgh Pennsylvania
Not listed Nashville Tennessee
Not listed Dallas Texas
Not listed Madison Wisconsin
Not listed Milwaukee Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01114737, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 31, 2016 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01114737 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →