Left Atrial Pressure Monitoring to Optimize Heart Failure Therapy
Public ClinicalTrials.gov record NCT01121107. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Left Atrial Pressure Monitoring to Optimize Heart Failure Therapy Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this clinical study is to evaluate the safety and clinical effectiveness of use of a physician-directed, patient self-management system, guided by left atrial pressure measurements, for use in patients with heart failure. The system allows patients to adjust their HF medications daily based on a physician-directed prescription plan and their current HF status, similar to the manner in which diabetes patients manage their insulin therapy. The goal of the LAPTOP-HF study is to demonstrate reductions in episodes of worsening heart failure (HF) and hospitalizations in patients who are managed with the left atrial pressure (LAP) management system (treatment group) versus those who receive only the current standard of care (control group).
Study identification
- NCT ID
- NCT01121107
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 486 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2010 (Type not available)
- Primary completion
- Apr 2015 (Actual)
- Completion
- Apr 2015 (Actual)
- Last update posted
- Jul 21, 2023
2010 – 2015
United States locations
- U.S. sites
- 63
- U.S. states
- 27
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cardiovascular Consultants Ltd | Phoenix | Arizona | 85032 | — |
| St. Jude Hospital | Fullerton | California | 92629 | — |
| Glendale Memorial Hospital and Medical Center | Glendale | California | 91204 | — |
| Scripps Green Hospital | La Jolla | California | 92037 | — |
| USC University Hospital | Los Angeles | California | 90033 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| VA Palo Alto Medical Center | Palo Alto | California | 95054 | — |
| Sutter Memorial Hospital | Sacramento | California | 95819 | — |
| University of California at San Francisco | San Francisco | California | 94143 | — |
| Pacific Heart Institute | Santa Monica | California | 90404 | — |
| Radiant Research | Santa Rosa | California | 95054 | — |
| Shands Jacksonville | Jacksonville | Florida | 32209 | — |
| Tampa General Hospital | Tampa | Florida | 33606 | — |
| The Emory Clinic - Crawford Long Hospital | Atlanta | Georgia | 30308 | — |
| St. Joseph's Hospital | Atlanta | Georgia | 30324 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60565 | — |
| Advocate Health and Hospitals Corporation | Oakbrook Terrace | Illinois | 60181 | — |
| Iowa Heart Center | Des Moines | Iowa | 50314 | — |
| Mid-America Cardiology Associates, PC | Kansas City | Kansas | 66160 | — |
| University of Kentucky | Lexington | Kentucky | 40515 | — |
| Jewish Hospital | Louisville | Kentucky | 40202 | — |
| Louisiana State University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Massachusettts Medical Center | Worcester | Massachusetts | 01655 | — |
| Trinity Health - Michigan d/b/a Michigan Heart | Ann Arbor | Michigan | 48104 | — |
| MidMichigan Physicians Group | Midland | Michigan | 48640 | — |
| Beaumont Hospital, Royal Oak | Royal Oak | Michigan | 48314 | — |
| Minneapolis Heart Institute | Minneapolis | Minnesota | 55410 | — |
| St. Luke's Hospital | Kansas City | Missouri | 64111 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Bryan LGH Heart Institute | Lincoln | Nebraska | 68506 | — |
| Morristown Memorial Hospital | Morristown | New Jersey | 07940 | — |
| University of Medicine & Dentistry of New Jersey | Newark | New Jersey | 07940 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Sanger Clinic | Charlotte | North Carolina | 29601 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Northeast Ohio Cardiovascular | Akron | Ohio | 44304 | — |
| The Linder Center | Cincinnati | Ohio | 45227 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| VA Medical Center Cleveland | Cleveland | Ohio | 44202 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Oklahoma Cardiovascular Research Group | Oklahoma City | Oklahoma | 73120 | — |
| Providence Heart and Vascular Institute | Portland | Oregon | 97225 | — |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17603 | — |
| Lancaster Heart Foundation | Lancaster | Pennsylvania | 17603 | — |
| Allegheny Singer Research Institute | Pittsburgh | Pennsylvania | 15212 | — |
| VA Pittsburgh Healthcare System | Pittsburgh | Pennsylvania | 15240 | — |
| Main Line Health Heart Center: Lankenau Hospitals | Wynnewood | Pennsylvania | 19096 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29403 | — |
| Baptist Memorial Hospital | Memphis | Tennessee | 38120 | — |
| Vanderbilt Medical Center | Nashville | Tennessee | 37212 | — |
| Austin Heart | Austin | Texas | 78703 | — |
| Texas Cardiac Arrhythmia Research Foundation | Austin | Texas | 78705 | — |
| Memorial Hermann Hospital | Houston | Texas | 77030 | — |
| Methodist Hospital Research Institute | Houston | Texas | 77030 | — |
| Texas Heart Institute | Houston | Texas | 77030 | — |
| Intermountain Heart Rhythm Specialists | Murray | Utah | 80134 | — |
| McKay-Dee Heart Services | Ogden | Utah | 84403 | — |
| University of Virginia Medical Center | Charlottesville | Virginia | 22908 | — |
| Sentara Hospitals and Sentara Cardiovascular Research Institute | Norfolk | Virginia | 23507 | — |
| Aurora Sinai Medical Center | Milwaukee | Wisconsin | 53201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01121107, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 21, 2023 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01121107 live on ClinicalTrials.gov.