A Study Comparing CO-1.01 With Gemcitabine as First Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma (LEAP)
Public ClinicalTrials.gov record NCT01124786. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Randomized, Open-Label, Multicenter Study Comparing CO-1.01 With Gemcitabine as First-Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether CO-1.01 is safe and effective in the treatment of patients with metastatic pancreatic cancer and low hENT1 expression compared with gemcitabine.
Study identification
- NCT ID
- NCT01124786
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 367 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2010 (Type not available)
- Primary completion
- Nov 2012 (Actual)
- Completion
- Jun 2013 (Actual)
- Last update posted
- Apr 17, 2014
2010 – 2013
United States locations
- U.S. sites
- 21
- U.S. states
- 13
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Center for Hematology Oncology | Glendale | Arizona | 85306 | — |
| Wilshire Oncology Medical Group, Inc. | Corona | California | 92879 | — |
| White Memorial Medical Center | Los Angeles | California | 90033 | — |
| Cancer Care Institute | Los Angeles | California | 90036 | — |
| Newport Cancer Care Medical | Newport Beach | California | 92660 | — |
| Hematology Oncology Associates | Oakland | California | 94609 | — |
| Sharp Clinical Oncology Research | San Diego | California | 92123 | — |
| Rocky Mountain Cancer Centers | Denver | Colorado | 80218 | — |
| Hartford Hospital Clinical Research | Hartford | Connecticut | 06102 | — |
| Oncology Associates of Bridgeport | Trumbull | Connecticut | 06611 | — |
| Annapolis Oncology Center | Annapolis | Maryland | 21401 | — |
| Virginia Piper Cancer Institute | Minneapolis | Minnesota | 55407 | — |
| The Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| New Mexico Cancer Care Alliance | Albuquerque | New Mexico | 87109 | — |
| Arena Oncology Associates, PC | Lake Success | New York | 11042 | — |
| Bend Memorial Clinic | Bend | Oregon | 97701 | — |
| Cancer Center of the Carolinas | Greenville | South Carolina | 29605 | — |
| Cancer Specialists of South Texas, P.A. | Corpus Christi | Texas | 78412 | — |
| Valley Cancer Associates | Harlingen | Texas | 78550 | — |
| South Texas Oncology and Hematology, PA | San Antonio | Texas | 78229 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 74 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01124786, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 17, 2014 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01124786 live on ClinicalTrials.gov.