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Completed Phase 2 Interventional

Imetelstat as Maintenance Therapy After Initial Induction Chemotherapy in Non-small Cell Lung Cancer (NSCLC)

ClinicalTrials.gov ID: NCT01137968

Public ClinicalTrials.gov record NCT01137968. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 4:25 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Phase II Study of Imetelstat as Maintenance Therapy After Initial Induction Chemotherapy for Advance Non-small Cell Lung Cancer(NSCLC)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this is to evaluate the efficacy and safety of imetelstat (GRN163L) as maintenance therapy for patients with advanced stage NSCLC who have not progressed after 4 cycles of platinum based therapy. Participants will be randomized in a 2:1 ratio to imetelstat + standard of care versus standard of care alone. Participants who received bevacizumab with their induction chemotherapy will continue to receive bevacizumab on this study.

Study identification

NCT ID
NCT01137968
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Geron Corporation
Industry
Enrollment
116 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2010
Primary completion
Aug 31, 2013
Completion
Aug 31, 2013
Last update posted
Jan 25, 2016

2010 – 2013

United States locations

U.S. sites
26
U.S. states
17
U.S. cities
26
Facility City State ZIP Site status
Achieve Clinical Research, Llc Birmingham Alabama 35216
Clearview Cancer Institute Huntsville Alabama 35805
Pacific Cancer Medical Center, Inc. Anaheim California 92801
Cancer Care Associates of Fresno Medical Group Inc Fresno California 93720
St. Joseph's Hospital Orange California 92868
Kaiser Permanente Medical Center Vallejo California 94589
University of Colorado Denver School of Medicine Aurora Colorado 80045
Florida Cancer Specialists Fort Myers Florida 33901
Integrated Community Oncology Network Jacksonville Florida 32256
H. Moffitt Lee Cancer Center Tampa Florida 33612
Ingalls Memorial Hospital Harvey Illinois 60426
Cancer Center of Kansas Wichita Kansas 67214
Montgomery Cancer Center Mount Sterling Kentucky 40353
Auerbach Hematology Oncology Baltimore Maryland 21237
Karmanos Cancer Institute Detroit Michigan 48201
Hematology Oncology Centers Billings Montana 59101
Blumenthal Cancer Center Charlotte North Carolina 28204
Kaiser Northwest Portland Oregon 97227
South Carolina Oncology Associates Columbia South Carolina 29210
The Jones Clinic Germantown Tennessee 38138
Sarah Cannon Research Institute Nashville Tennessee 37203
UT Southwestern Medical Center Dallas Texas 75390
Scott and White Memorial Hospital (Texas A & M) Temple Texas 76508
Swedish Cancer Institute Seattle Washington 98104
Northwest Medical Specialties Tacoma Washington 98405
University of Wisconsin Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01137968, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 25, 2016 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01137968 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →