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Completed Phase 1 Interventional

Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors

ClinicalTrials.gov ID: NCT01141244

Public ClinicalTrials.gov record NCT01141244. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 12:03 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Study of Temsirolimus in Combination With Irinotecan and Temozolomide in Children, Adolescents, and Young Adults With Relapsed or Refractory Solid Tumors

Study identification

NCT ID
NCT01141244
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
National Cancer Institute (NCI)
NIH
Enrollment
72 participants

Conditions and interventions

Interventions

  • temsirolimus Drug
  • temozolomide Drug
  • irinotecan hydrochloride Drug
  • laboratory biomarker analysis Other

Drug · Other

Eligibility (public fields only)

Age range
2 Years to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2010
Primary completion
Oct 31, 2013
Completion
Not listed
Last update posted
Apr 9, 2014

Started 2010

United States locations

U.S. sites
23
U.S. states
18
U.S. cities
21
Facility City State ZIP Site status
Children's Hospital of Alabama Birmingham Alabama 35233
University of Alabama at Birmingham Birmingham Alabama 35294
Childrens Hospital of Orange County Orange California 92868-3874
University of California San Francisco Medical Center-Parnassus San Francisco California 94143
Children's National Medical Center Washington D.C. District of Columbia 20010
Lurie Children's Hospital-Chicago Chicago Illinois 60614
Indiana University Medical Center Indianapolis Indiana 46202
Riley Hospital for Children Indianapolis Indiana 46202
Mark O Hatfield-Warren Grant Magnuson Clinical Center Bethesda Maryland 20892
Dana-Farber Cancer Institute Boston Massachusetts 02115
C S Mott Children's Hospital Ann Arbor Michigan 48109
University of Minnesota Medical Center-Fairview Minneapolis Minnesota 55455
Washington University School of Medicine St Louis Missouri 63110
Columbia University Medical Center New York New York 10032
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229
Oregon Health and Science University Portland Oregon 97239
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
Children's Hospital of Pittsburgh of UPMC Pittsburgh Pennsylvania 15224
St. Jude Children's Research Hospital Memphis Tennessee 38105
University of Texas Southwestern Medical Center Dallas Texas 75390
Baylor College of Medicine Houston Texas 77030
Seattle Children's Hospital Seattle Washington 98105
Midwest Children's Cancer Center Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01141244, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 9, 2014 · Synced Jun 25, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01141244 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →