Efficacy and Safety Study of Abatacept Subcutaneous Plus Methotrexate in Inducing Remission in Adults With Very Early Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT01142726. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3b, Randomized, Active Controlled Trial to Evaluate the Efficacy and Safety of Abatacept SC in Combination With Methotrexate in Inducing Clinical Remission Compared to Methotrexate Monotherapy in Adults With Very Early RA
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of the protocol is to demonstrate the ability of abatacept plus methotrexate to induce remission in patients with very early rheumatoid arthritis after 12 months of treatment and to maintain remission following 6 months of drug withdrawal.
Study identification
- NCT ID
- NCT01142726
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 511 participants
Conditions and interventions
Conditions
Interventions
- Abatacept Drug
- Methotrexate Drug
- Abatacept placebo Drug
- Methotrexate placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2010 (Type not available)
- Primary completion
- Sep 2013 (Actual)
- Completion
- Oct 2014 (Actual)
- Last update posted
- Jan 14, 2016
2010 – 2014
United States locations
- U.S. sites
- 15
- U.S. states
- 13
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Rheumatology Associates Of North Alabama, P.C. | Huntsville | Alabama | 35801 | — |
| St. Joseph'S Mercy Clinic | Hot Springs | Arkansas | 71913 | — |
| Sarasota Arthritis Research Center | Sarasota | Florida | 34239 | — |
| Coeur D'Alene Arthrit Clin | Coeur d'Alene | Idaho | 83814 | — |
| Johns Hopkins University Division Of Rheumatology | Baltimore | Maryland | 21224 | — |
| Clinical Pharmacology Study Group | Worcester | Massachusetts | 01605 | — |
| Arthritis Associates Of Mississippi | Jackson | Mississippi | 39202 | — |
| Physician Research Collaboration, Llc | Lincoln | Nebraska | 68516 | — |
| Piedmont Rheumatology, Pa | Hickory | North Carolina | 28602 | — |
| Carolina Arthritis Associates | Wilmington | North Carolina | 28401 | — |
| Metrohealth Medical Center | Cleveland | Ohio | 44109 | — |
| Isam A. Diab, Md | Middleburg | Ohio | 44130 | — |
| Alan J. Kivitz, Md, Cpi | Duncansville | Pennsylvania | 16635 | — |
| Mitchell C. Feinman, Md | Orangeburg | South Carolina | 29118 | — |
| Kurt Oelke, Md | Glendale | Wisconsin | 53217 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 58 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01142726, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 14, 2016 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01142726 live on ClinicalTrials.gov.