A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin
Public ClinicalTrials.gov record NCT01143246. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center, Randomized, Placebo-controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Lucassin® (Terlipressin) (The REVERSE Study)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is designed to evaluate the efficacy and safety of intravenous terlipressin versus placebo for the treatment of type 1 hepatorenal syndrome (HRS) in participants receiving standard of care albumin therapy.
Study identification
- NCT ID
- NCT01143246
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 196 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 11, 2010 (Actual)
- Primary completion
- Feb 2013 (Actual)
- Completion
- May 10, 2013 (Actual)
- Last update posted
- Nov 29, 2022
2010 – 2013
United States locations
- U.S. sites
- 71
- U.S. states
- 33
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Banner Good Samaritan Medical Center/Liver Disease Center | Phoenix | Arizona | 85006 | — |
| Mayo Clinic Arizona | Phoenix | Arizona | 85054 | — |
| University of Arizona Medical Center South Campus | Tucson | Arizona | 85713 | — |
| University of Arizona Liver Research Institute | Tucson | Arizona | 85724 | — |
| Arrowhead Regional Medical Center | Colton | California | 92324 | — |
| SCTI Research Foundation | Coronado | California | 92118 | — |
| Scripps Clinic | La Jolla | California | 92037 | — |
| USC University Hospital | Los Angeles | California | 90033 | — |
| UC Davis Medical Center | Sacramento | California | 95817 | — |
| Veteran's Administration Medical Center | San Diego | California | 92161 | — |
| California Pacific Medical Center | San Francisco | California | 94115 | — |
| University of Colorado Denver | Aurora | Colorado | 80045 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06520 | — |
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Indiana University Health - University Hospital | Indianapolis | Indiana | 46202 | — |
| Iowa City VA Health Care System | Iowa City | Iowa | 52246 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Kentucky Chandler Medical Center | Lexington | Kentucky | 40536 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Tulane Medical Center | New Orleans | Louisiana | 70112 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Beth Lsrael Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Lahey Clinic Medical Center | Burlington | Massachusetts | 01805 | — |
| University of Massachusetts Medical Center | Worcester | Massachusetts | 01655 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| University of Minnesota | Minneapolis | Minnesota | 55414 | — |
| Saint Luke's Hospital | Kansas City | Missouri | 64111 | — |
| Saint Louis University | St Louis | Missouri | 63110 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Bellevue Hospital | New York | New York | 10016 | — |
| NYU Langhorn Medical Center | New York | New York | 10016 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| New York Medical College/Westchester Medical Center | Valhalla | New York | 10595 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28203 | — |
| University of Cincinnati, Internal Medicine-Digestive Diseases | Cincinnati | Ohio | 45267 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| INTEGRIS Baptist Medical Center | Oklahoma City | Oklahoma | 73112 | — |
| Orgeon Health & Science University | Portland | Oregon | 97239 | — |
| Drexel University College of Medicine | Philadelphia | Pennsylvania | 19102 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Albert Einstein Medical Center | Philadelphia | Pennsylvania | 19141 | — |
| VA Pittsburgh Healthcare System | Pittsburgh | Pennsylvania | 15240 | — |
| WJB Dorn VA Medical Center | Columbia | South Carolina | 29209 | — |
| Vanderbilt Medical Center | Nashville | Tennessee | 37212 | — |
| Dallas VA Medical Center | Dallas | Texas | 75216 | — |
| Baylor University Medical Center | Dallas | Texas | 75246 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Baylor All Saints Medical Center | Fort Worth | Texas | 76104 | — |
| The University of Texas Medical Branch at Galveston | Galveston | Texas | 77555 | — |
| St. Luke's Advanced Liver Therapies | Houston | Texas | 77030 | — |
| The Methodist Hospital | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at Houston - Memorial Hermann Hospital | Houston | Texas | 77030 | — |
| Methodist Specialty Transplant Hospital Lab | San Antonio | Texas | 78229 | — |
| The University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| University of Texas Health Science Center | San Antonio | Texas | 78229 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| McGuire DVAMC | Richmond | Virginia | 23249 | — |
| Virginia Commonwealth University Health System | Richmond | Virginia | 23298 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01143246, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 29, 2022 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01143246 live on ClinicalTrials.gov.