Role of Donor Genetics and Recipient Genetics in Kidney Transplant Outcomes
Public ClinicalTrials.gov record NCT01143532. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Background: \- Genetic variation in a particular chromosome is a major contributor to the increased risk for kidney disease that is common in people of African descent, although the specific gene, mutations, and other aspects of the variations remain to be determined. By studying the outcomes of kidney transplant in donors and recipients of African descent, researchers hope to better understand the effects of this genetic variation on the success of kidney transplants. Objectives: \- To examine possible connections between genetic variations and kidney transplant outcomes for donors and recipients. Eligibility: * Participants in kidney transplant where both donor and recipient were of black African descent. * Eligible transplants include both living donor and deceased donor. Design: * The study will involve one visit of up to 8 hours. * All participants will provide a detailed personal and family medical history. * All participants will provide blood and urine samples, including a 24-hour urine collection, to test kidney function and collect material for genetic testing. * Donor participants will also have a magnetic resonance imaging (MRI) scan of their remaining kidney.
Study identification
- NCT ID
- NCT01143532
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 26 participants
Conditions and interventions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 12, 2010 (Actual)
- Primary completion
- Oct 19, 2015 (Actual)
- Completion
- Oct 19, 2015 (Actual)
- Last update posted
- Feb 24, 2023
2010 – 2015
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| National Institutes of Health Clinical Center | Bethesda | Maryland | 20892 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01143532, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 24, 2023 · Synced Oct 3, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01143532 live on ClinicalTrials.gov.