ClinicalTrials.gov record
Evaluation of Cardiovascular Outcomes in Patients With Type 2 Diabetes After Acute Coronary Syndrome During Treatment With AVE0010 (Lixisenatide)
ClinicalTrials.gov ID: NCT01147250
Public ClinicalTrials.gov record NCT01147250. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate Cardiovascular Outcomes During Treatment With Lixisenatide in Type 2 Diabetic Patients After an Acute Coronary Syndrome
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Primary Objective: \- To demonstrate that lixisenatide can reduce cardiovascular (CV) morbidity and mortality (composite endpoint of CV death, non-fatal myocardial infarction (MI), non-fatal stroke, hospitalization for unstable angina) compared to placebo in type 2 diabetic participants who recently experienced an acute coronary syndrome (ACS) event. Secondary Objectives: To demonstrate that when compared to placebo, lixisenatide can reduce: * composite endpoint of CV death, non-fatal MI, non-fatal stroke, hospitalization for unstable angina, or hospitalization for heart failure. * composite endpoint of CV death, non-fatal MI, non-fatal stroke, hospitalization for unstable angina, hospitalization for heart failure, or coronary revascularization procedure. * urinary albumin excretion (based on the urinary albumin/creatinine ratio). To assess the safety and tolerability of lixisenatide.
Study identification
- NCT ID
- NCT01147250
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 6,068 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 30 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2010 (Type not available)
- Primary completion
- Feb 2015 (Actual)
- Completion
- Feb 2015 (Actual)
- Last update posted
- Dec 20, 2016
2010 – 2015
United States locations
- U.S. sites
- 200
- U.S. states
- 37
- U.S. cities
- 163
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigational Site Number 840415 | Birmingham | Alabama | 35203 | — |
| Investigational Site Number 840307 | Foley | Alabama | 36535 | — |
| Investigational Site Number 840692 | Mobile | Alabama | 36604 | — |
| Investigational Site Number 840037 | Mobile | Alabama | 36608 | — |
| Investigational Site Number 840210 | Mobile | Alabama | 36609 | — |
| Investigational Site Number 840326 | Muscle Shoals | Alabama | 35661 | — |
| Investigational Site Number 840393 | Toney | Alabama | 35773 | — |
| Investigational Site Number 840656 | Mesa | Arizona | 85206 | — |
| Investigational Site Number 840506 | Phoenix | Arizona | 85012 | — |
| Investigational Site Number 840520 | Phoenix | Arizona | 85020 | — |
| Investigational Site Number 840322 | Phoenix | Arizona | 85032 | — |
| Investigational Site Number 840250 | Tempe | Arizona | 85284 | — |
| Investigational Site Number 840042 | Tucson | Arizona | 85723 | — |
| Investigational Site Number 840303 | Hot Springs | Arkansas | 71913 | — |
| Investigational Site Number 840184 | Jonesboro | Arkansas | 72401 | — |
| Investigational Site Number 840361 | Little Rock | Arkansas | 72204 | — |
| Investigational Site Number 840023 | Little Rock | Arkansas | 72205 | — |
| Investigational Site Number 840706 | Anaheim | California | 92801 | — |
| Investigational Site Number 840497 | Anaheim | California | 92804 | — |
| Investigational Site Number 840667 | Downey | California | 90242 | — |
| Investigational Site Number 840150 | Fresno | California | 93722 | — |
| Investigational Site Number 840624 | Hawthorne | California | 90250 | — |
| Investigational Site Number 840623 | Inglewood | California | 90301 | — |
| Investigational Site Number 840636 | Inglewood | California | 90301 | — |
| Investigational Site Number 840455 | La Mesa | California | 91942 | — |
| Investigational Site Number 840240 | Loma Linda | California | 92354 | — |
| Investigational Site Number 840262 | Long Beach | California | 90806 | — |
| Investigational Site Number 840606 | Long Beach | California | 90813 | — |
| Investigational Site Number 840694 | Los Angeles | California | 90024 | — |
| Investigational Site Number 840431 | Los Angeles | California | 90033 | — |
| Investigational Site Number 840135 | Los Angeles | California | 90073 | — |
| Investigational Site Number 840314 | Merced | California | 95348 | — |
| Investigational Site Number 840290 | Mission Viejo | California | 92691 | — |
| Investigational Site Number 840592 | National City | California | 91950 | — |
| Investigational Site Number 840275 | Northridge | California | 91328 | — |
| Investigational Site Number 840654 | Oakland | California | 94609 | — |
| Investigational Site Number 840351 | Orange | California | 92868 | — |
| Investigational Site Number 840689 | Orange | California | 92868 | — |
| Investigational Site Number 840582 | Pomona | California | 91767 | — |
| Investigational Site Number 840346 | Port Hueneme | California | 93041 | — |
| Investigational Site Number 840466 | Roseville | California | 95661 | — |
| Investigational Site Number 840575 | San Marino | California | 91108 | — |
| Investigational Site Number 840131 | Santa Ana | California | 82705 | — |
| Investigational Site Number 840335 | Santa Ana | California | 92704 | — |
| Investigational Site Number 840576 | Simi Valley | California | 93065 | — |
| Investigational Site Number 840414 | Sylmar | California | 91342 | — |
| Investigational Site Number 840395 | Ventura | California | 93003 | — |
| Investigational Site Number 840206 | Vista | California | 92081-7832 | — |
| Investigational Site Number 840480 | Westlake Village | California | 91361 | — |
| Investigational Site Number 840350 | Whittier | California | 90602 | — |
| Investigational Site Number 840093 | Colorado Springs | Colorado | 80910 | — |
| Investigational Site Number 840631 | Washington D.C. | District of Columbia | 20060 | — |
| Investigational Site Number 840044 | Washington D.C. | District of Columbia | 20422 | — |
| Investigational Site Number 840281 | Clearwater | Florida | 33755 | — |
| Investigational Site Number 840477 | Homosassa | Florida | 34448 | — |
| Investigational Site Number 840261 | Miami | Florida | 33135 | — |
| Investigational Site Number 840459 | Miami | Florida | 33155 | — |
| Investigational Site Number 840432 | Oviedo | Florida | 32765 | — |
| Investigational Site Number 840318 | Panama City | Florida | 32401 | — |
| Investigational Site Number 840056 | St. Petersburg | Florida | 33707 | — |
| Investigational Site Number 840295 | Wellington | Florida | 33449 | — |
| Investigational Site Number 840066 | Atlanta | Georgia | 30322 | — |
| Investigational Site Number 840446 | Atlanta | Georgia | 30322 | — |
| Investigational Site Number 840487 | Atlanta | Georgia | 30322 | — |
| Investigational Site Number 840578 | Blue Ridge | Georgia | 30513 | — |
| Investigational Site Number 840534 | Columbus | Georgia | 31904-5245 | — |
| Investigational Site Number 840447 | Duluth | Georgia | 30096 | — |
| Investigational Site Number 840499 | Duluth | Georgia | 30096 | — |
| Investigational Site Number 840536 | Idaho Falls | Idaho | 83404 | — |
| Investigational Site Number 840413 | Pocatello | Idaho | 83201 | — |
| Investigational Site Number 840519 | Arlington Heights | Illinois | 60005 | — |
| Investigational Site Number 840589 | Belleville | Illinois | 62220 | — |
| Investigational Site Number 840107 | Chicago | Illinois | 60415 | — |
| Investigational Site Number 840633 | Chicago | Illinois | 60611 | — |
| Investigational Site Number 840663 | Chicago | Illinois | 60612 | — |
| Investigational Site Number 840212 | Hines | Illinois | 60141 | — |
| Investigational Site Number 840345 | Joliet | Illinois | 60435 | — |
| Investigational Site Number 840681 | Peoria | Illinois | 61602 | — |
| Investigational Site Number 840360 | Elwood | Indiana | 46036 | — |
| Investigational Site Number 840676 | Gary | Indiana | 46409 | — |
| Investigational Site Number 840657 | Hammond | Indiana | 46320 | — |
| Investigational Site Number 840621 | Huntington | Indiana | 46750 | — |
| Investigational Site Number 840702 | Indianapolis | Indiana | 46202 | — |
| Investigational Site Number 840009 | Topeka | Kansas | 66606 | — |
| Investigational Site Number 840533 | Covington | Kentucky | 41011 | — |
| Investigational Site Number 840251 | Madisonville | Kentucky | 42431 | — |
| Investigational Site Number 840168 | Owensboro | Kentucky | 42303 | — |
| Investigational Site Number 840449 | Pikeville | Kentucky | 41501 | — |
| Investigational Site Number 840299 | Baton Rouge | Louisiana | 70808 | — |
| Investigational Site Number 840671 | Hammond | Louisiana | 70403 | — |
| Investigational Site Number 840470 | Metairie | Louisiana | 70006 | — |
| Investigational Site Number 840178 | Shreveport | Louisiana | 71130 | — |
| Investigational Site Number 840043 | Annapolis | Maryland | 21401 | — |
| Investigational Site Number 840639 | Catonsville | Maryland | 21228 | — |
| Investigational Site Number 840430 | Rockville | Maryland | 20852 | — |
| Investigational Site Number 840640 | Takoma Park | Maryland | 20912 | — |
| Investigational Site Number 840293 | Towson | Maryland | 21204 | — |
| Investigational Site Number 840019 | Alpena | Michigan | 49707 | — |
| Investigational Site Number 840352 | Buckley | Michigan | 49620 | — |
| Investigational Site Number 840555 | Chesterfield | Michigan | 48047 | — |
| Investigational Site Number 840411 | Dearborn | Michigan | 48124 | — |
| Investigational Site Number 840205 | Detroit | Michigan | 48235 | — |
| Investigational Site Number 840581 | Flint | Michigan | 48503 | — |
| Investigational Site Number 840404 | Kalamazoo | Michigan | 49048 | — |
| Investigational Site Number 840312 | Southfield | Michigan | 48075 | — |
| Investigational Site Number 840484 | Sterling Heights | Michigan | 48310 | — |
| Investigational Site Number 840219 | Duluth | Minnesota | 55805 | — |
| Investigational Site Number 840199 | Eagan | Minnesota | 55122 | — |
| Investigational Site Number 840196 | Biloxi | Mississippi | 39531 | — |
| Investigational Site Number 840445 | Kansas City | Missouri | 64111 | — |
| Investigational Site Number 840008 | Kansas City | Missouri | 64128 | — |
| Investigational Site Number 840091 | St Louis | Missouri | 63122 | — |
| Investigational Site Number 840046 | St Louis | Missouri | 63128 | — |
| Investigational Site Number 840678 | St Louis | Missouri | 63131 | — |
| Investigational Site Number 840400 | St Louis | Missouri | 63141 | — |
| Investigational Site Number 840337 | Kalispell | Montana | 59901 | — |
| Investigational Site Number 840509 | Lincoln | Nebraska | 68521 | — |
| Investigational Site Number 840007 | Omaha | Nebraska | 68131 | — |
| Investigational Site Number 840382 | Las Vegas | Nevada | 89102 | — |
| Investigational Site Number 840680 | Las Vegas | Nevada | 89102 | — |
| Investigational Site Number 840217 | Las Vegas | Nevada | 89148 | — |
| Investigational Site Number 840072 | Linden | New Jersey | — | — |
| Investigational Site Number 840628 | Ridgewood | New Jersey | 07450 | — |
| Investigational Site Number 840162 | Somerset | New Jersey | 08873 | — |
| Investigational Site Number 840285 | Albany | New York | 12206 | — |
| Investigational Site Number 840585 | Jamaica | New York | 11432 | — |
| Investigational Site Number 840348 | Mineola | New York | 11501 | — |
| Investigational Site Number 840119 | Northport | New York | 11768 | — |
| Investigational Site Number 840696 | Rosedale | New York | 14221 | — |
| Investigational Site Number 840310 | Asheville | North Carolina | 28805 | — |
| Investigational Site Number 840454 | Calabash | North Carolina | 28467 | — |
| Investigational Site Number 840672 | Charlotte | North Carolina | 28203 | — |
| Investigational Site Number 840152 | Charlotte | North Carolina | 28205 | — |
| Investigational Site Number 840344 | Elizabeth City | North Carolina | 27909 | — |
| Investigational Site Number 840328 | Greensboro | North Carolina | 27401 | — |
| Investigational Site Number 840513 | Greensboro | North Carolina | 27405 | — |
| Investigational Site Number 840504 | Greenville | North Carolina | 27858 | — |
| Investigational Site Number 840642 | Monroe | North Carolina | 28110 | — |
| Investigational Site Number 840481 | Raleigh | North Carolina | 27609 | — |
| Investigational Site Number 840381 | Wilmington | North Carolina | 28401 | — |
| Investigational Site Number 840532 | Winston-Salem | North Carolina | 27157-1071 | — |
| Investigational Site Number 840028 | Cincinnati | Ohio | 45219 | — |
| Investigational Site Number 840198 | Cincinnati | Ohio | 45220 | — |
| Investigational Site Number 840543 | Columbus | Ohio | 43201 | — |
| Investigational Site Number 840456 | Dayton | Ohio | 45439 | — |
| Investigational Site Number 840368 | Marion | Ohio | 43302 | — |
| Investigational Site Number 840427 | Bend | Oregon | 97701 | — |
| Investigational Site Number 840422 | Portland | Oregon | 97201-3098 | — |
| Investigational Site Number 840511 | Portland | Oregon | 97227-1191 | — |
| Investigational Site Number 840560 | Butler | Pennsylvania | 16001 | — |
| Investigational Site Number 840464 | Clark Summit | Pennsylvania | 18411 | — |
| Investigational Site Number 840401 | Pittsburgh | Pennsylvania | 15220 | — |
| Investigational Site Number 840266 | Providence | Rhode Island | 02908 | — |
| Investigational Site Number 840223 | Anderson | South Carolina | 29621 | — |
| Investigational Site Number 840353 | Columbia | South Carolina | 29201 | — |
| Investigational Site Number 840529 | Greenville | South Carolina | 29605 | — |
| Investigational Site Number 840550 | Greer | South Carolina | 29651 | — |
| Investigational Site Number 840258 | Myrtle Beach | South Carolina | 29572 | — |
| Investigational Site Number 840309 | Taylors | South Carolina | 29687-4105 | — |
| Investigational Site Number 840551 | Rapid City | South Dakota | 57701 | — |
| Investigational Site Number 840524 | Bartlett | Tennessee | 38133 | — |
| Investigational Site Number 840308 | Chattanooga | Tennessee | 37404 | — |
| Investigational Site Number 840047 | Germantown | Tennessee | 38138 | — |
| Investigational Site Number 840313 | Jackson | Tennessee | 38305 | — |
| Investigational Site Number 840625 | Memphis | Tennessee | 38114 | — |
| Investigational Site Number 840637 | Memphis | Tennessee | 38163 | — |
| Investigational Site Number 840096 | Nashville | Tennessee | 37208 | — |
| Investigational Site Number 840388 | Nashville | Tennessee | 37232 | — |
| Investigational Site Number 840473 | Dallas | Texas | 75246 | — |
| Investigational Site Number 840677 | Edinburg | Texas | 78539 | — |
| Investigational Site Number 840698 | El Paso | Texas | 79925 | — |
| Investigational Site Number 840439 | Fair Oaks Ranch | Texas | 78015 | — |
| Investigational Site Number 840164 | Houston | Texas | 77081 | — |
| Investigational Site Number 840545 | Longview | Texas | 75605 | — |
| Investigational Site Number 840385 | Lubbock | Texas | 79409 | — |
| Investigational Site Number 840530 | Lubbock | Texas | 79409 | — |
| Investigational Site Number 840174 | Marshall | Texas | 75670 | — |
| Investigational Site Number 840565 | Plano | Texas | 75024 | — |
| Investigational Site Number 840608 | Richmond | Texas | 77469 | — |
| Investigational Site Number 840573 | San Antonio | Texas | 78258 | — |
| Investigational Site Number 840564 | Sugarland | Texas | 77479 | — |
| Investigational Site Number 840241 | Waco | Texas | 76708 | — |
| Investigational Site Number 840232 | American Fork | Utah | 84003 | — |
| Investigational Site Number 840471 | Draper | Utah | 84020 | — |
| Investigational Site Number 840503 | Charlottesville | Virginia | 22908-0679 | — |
| Investigational Site Number 840180 | Chesapeake | Virginia | 23320 | — |
| Investigational Site Number 840465 | Chesapeake | Virginia | 23321 | — |
| Investigational Site Number 840128 | Chesapeake | Virginia | 23323 | — |
| Investigational Site Number 840045 | Norfolk | Virginia | 23502 | — |
| Investigational Site Number 840213 | Norfolk | Virginia | 23510 | — |
| Investigational Site Number 840001 | Richmond | Virginia | 23219 | — |
| Investigational Site Number 840286 | Roanoke | Virginia | 24014 | — |
| Investigational Site Number 840170 | Olympia | Washington | 98506 | — |
| Investigational Site Number 840094 | Spokane | Washington | 99207 | — |
| Investigational Site Number 840343 | Spokane | Washington | 99207 | — |
| Investigational Site Number 840268 | Spokane | Washington | 99220 | — |
| Investigational Site Number 840061 | Tacoma | Washington | 98405 | — |
| Investigational Site Number 840613 | Fairmount | Wisconsin | 26554 | — |
| Investigational Site Number 840121 | La Crosse | Wisconsin | 54601 | — |
| Investigational Site Number 840493 | Milwaukee | Wisconsin | 53211 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 629 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01147250, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 20, 2016 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01147250 live on ClinicalTrials.gov.