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Completed Phase 2 Interventional Results available

Trial of Exemestane +/- MM-121 in Postmenopausal Women With Locally Advanced or Metastatic Estrogen Receptor Positive and/or Progesterone Receptor Positive Her2 Negative Breast Cancer

ClinicalTrials.gov ID: NCT01151046

Public ClinicalTrials.gov record NCT01151046. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 8:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Double-Blind Phase 2 Trial of Exemestane +/- MM-121 in Postmenopausal Women With Locally Advanced or Metastatic Estrogen Receptor Positive (ER+) and/or Progesterone Receptor Positive (PR+) Her2 Negative Breast Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To determine whether the combination MM-121 + Exemestane in ER+ and/or PR+ breast cancer patients is more effective than Exemestane alone

Study identification

NCT ID
NCT01151046
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Merrimack Pharmaceuticals
Industry
Enrollment
118 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2010
Primary completion
May 31, 2014
Completion
Aug 31, 2014
Last update posted
May 11, 2016

2010 – 2014

United States locations

U.S. sites
18
U.S. states
8
U.S. cities
16
Facility City State ZIP Site status
Achieve Clinical Research Birmingham Alabama 35209
Achieve Clinical Research Birmingham Alabama 35216
Arizona Center for Cancer Care Glendale Arizona 85306
Pacific Cancer Medical Center Anaheim California 92801
Beverly Hills Cancer Center Beverly Hills California 90211
Wilshire Oncology Medical Group, Inc. Corona California 92879
Southwest Cancer Center Escondido California 92025
Hematology Oncology Associates, INC. Oakland California 94609
San Jose Medical Center San Jose California 95124
Central Coast Medical Oncology Corporation Santa Maria California 93454
Pasco-Pinellas Oncology New Port Richey Florida 34652
Hematology Oncology Associates of the Treasure Coast Port Saint Lucie Florida 34952
Rush University Medical Center Chicago Illinois 60612
Indiana University Simon Cancer Center Indianapolis Indiana 46202
Horizon Oncology Center Lafayette Indiana 47905
Massachusetts General Hospital Boston Massachusetts 02114
Tennessee Cancer Specialists Oncology Clinical Trials Center for Biomedical Research Knoxville Tennessee 37909
Tennessee Cancer Specialists, Oncology Clincial Trials Center for Biomedical Research Knoxville Tennessee 37909

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01151046, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 11, 2016 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01151046 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →