A Study of CDX-011 (CR011-vcMMAE) in Patients With Advanced GPNMB-expressing Breast Cancer
Public ClinicalTrials.gov record NCT01156753. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Randomized, Multicenter Study of CDX-011 (CR011-vcMMAE) in Patients With Advanced GPNMB-expressing Breast Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to see whether CDX-011 is effective in treating patients who have advanced breast cancer that makes a protein called glycoprotein NMB (GPNMB), and who have already received (or were not candidates for) all available approved therapies for their breast cancer. This study will also further characterize the safety of CDX-011 treatment in this patient population.
Study identification
- NCT ID
- NCT01156753
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 120 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2010 (Type not available)
- Primary completion
- Oct 2012 (Actual)
- Completion
- Nov 2012 (Actual)
- Last update posted
- Jul 2, 2017
2010 – 2012
United States locations
- U.S. sites
- 24
- U.S. states
- 15
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University of Alabama at Birmingham Comprehensive Cancer Center | Birmingham | Alabama | 35294 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| Breastlink Medical Group | Long Beach | California | 90806 | — |
| The Angeles Clinic and Research Institute | Los Angeles | California | 90025 | — |
| USC/Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94143 | — |
| Florida Cancer Specialists | West Coast | Florida | — | — |
| Peachtree Hematology-Oncology Consultants PC | Atlanta | Georgia | 30318 | — |
| Georgia Cancer Specialists | Atlanta | Georgia | 30341 | — |
| Orchard Healthcare Research Inc. | Skokie | Illinois | 60076 | — |
| Cancer Treatment Centers of America at Midwestern Regional Medical Center | Zion | Illinois | 60099 | — |
| Cancer Care of Louisiana | New Orleans | Louisiana | 70115 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Montana Cancer Institute Foundation | Missoula | Montana | 59802 | — |
| Clinical Research Alliance Inc. | Lake Success | New York | 11042 | — |
| Weill Cornell Breast Center/Weill Cornell Medical College | New York | New York | 10065 | — |
| Montefiore-Einstein Cancer Center | The Bronx | New York | 10467 | — |
| Levine Cancer Institute/Blumenthal Cancer Center | Charlotte | North Carolina | 28203 | — |
| Oncology Hematology Care | Cincinnati | Ohio | 45242 | — |
| Guthrie Clinic, Ltd. | Sayre | Pennsylvania | 18840 | — |
| South Carolina Oncology Associates | Columbia | South Carolina | 29210 | — |
| Santee Hematology Oncology, Inc. | Sumter | South Carolina | 29150 | — |
| Center for Biomedical Research | Knoxville | Tennessee | 37909 | — |
| Sarah Cannon Research Institution | Nashville | Tennessee | 37203 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01156753, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 2, 2017 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01156753 live on ClinicalTrials.gov.