To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee
Public ClinicalTrials.gov record NCT01160822. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double Blind, Placebo and Naproxen Controlled, Multi-center, Study to Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee
Study identification
- NCT ID
- NCT01160822
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 169 participants
Conditions and interventions
Conditions
Interventions
- Canakinumab Biological
- Naproxen Drug
- Placebo to Naproxen Drug
- Placebo to canakinumab Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 40 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2010
- Primary completion
- Jun 30, 2011
- Completion
- Jun 30, 2011
- Last update posted
- Oct 29, 2012
2010 – 2011
United States locations
- U.S. sites
- 8
- U.S. states
- 7
- U.S. cities
- 8
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group, LLC | Anniston | Alabama | 36207 | — |
| Arizona Arthritis & Rheumatology Research, PLLC | Mesa | Arizona | 85202 | — |
| San Diego Arthritis & Osteoporosis Medical Clinic | San Diego | California | 92108 | — |
| Westlake Medical Research | Westlake Village | California | 91361 | — |
| Rush-Presbyterian St. Lukes Medical Center | Chicago | Illinois | 60612 | — |
| Cotton O'Neil Clinical Research Institute | Topeka | Kansas | 66606 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Volunteer Research Group | Knoxville | Tennessee | 37920 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01160822, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 29, 2012 · Synced May 11, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01160822 live on ClinicalTrials.gov.