The HeartWare™ Ventricular Assist System as Destination Therapy of Advanced Heart Failure: the ENDURANCE Trial
Public ClinicalTrials.gov record NCT01166347. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Randomized, Controlled, Un-blinded, Multi-Center Clinical Trial to Evaluate the HeartWare™ Ventricular Assist System (VAS) for Destination Therapy of Advanced Heart Failure
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the safety and effectiveness of the HeartWare Ventricular Assist System in patients with chronic Stage D/ New York Heart Association (NYHA) Class IIIB/IV left ventricular failure who have received and failed optimal medical therapy, and who are ineligible for cardiac transplantation.
Study identification
- NCT ID
- NCT01166347
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 451 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2010 (Type not available)
- Primary completion
- May 2014 (Actual)
- Completion
- May 2017 (Actual)
- Last update posted
- Sep 6, 2018
2010 – 2017
United States locations
- U.S. sites
- 48
- U.S. states
- 27
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Mayo Clinic Hospital - Phoenix | Phoenix | Arizona | 85054 | — |
| The University of Southern California | Los Angeles | California | 90033 | — |
| Sharp Memorial | San Diego | California | 92123 | — |
| Stanford University School of Medicine | Stanford | California | 94305 | — |
| University of Colorado Hospital - Leprino | Aurora | Colorado | 80045 | — |
| Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| University of Florida - Gainesville | Gainesville | Florida | 32610 | — |
| University of Miami/Jackson Memorial Hospital | Miami | Florida | 33136 | — |
| Tampa Transplant Institute/Tampa General Hospital | Tampa | Florida | 33606 | — |
| The Emory Clinic Inc. | Atlanta | Georgia | 30322 | — |
| Saint Joseph Hospital of Atlanta | Atlanta | Georgia | 30342 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453 | — |
| IU Health Methodist | Indianapolis | Indiana | 46202 | — |
| Saint Vincent Health | Indianapolis | Indiana | 46260 | — |
| Jewish Hospital | Louisville | Kentucky | 40202 | — |
| John Ochsner Heart & Vascular Institute | New Orleans | Louisiana | 70115 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| University of Michigan Hospital | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Abbott Northwestern | Minneapolis | Minnesota | 55407 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| St. Mary's Hospital - Mayo | Rochester | Minnesota | 55902 | — |
| Washington University/Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| New York Presbyterian Hospital/Columbia | New York | New York | 10032 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University Medical Center | Columbus | Ohio | 43210 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| University of Pennsylvania Hospital | Philadelphia | Pennsylvania | 19104 | — |
| UPMC Presbyterian | Pittsburgh | Pennsylvania | 15213 | — |
| Baylor University Medical Center | Dallas | Texas | 75246 | — |
| University of Texas - South Western | Dallas | Texas | 75390 | — |
| Texas Heart Institute | Houston | Texas | 77030 | — |
| The Methodist Hospital | Houston | Texas | 77030 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| Innova Heart and Vascular Institute Research - Cardiac Vascular & Thoracic Surgery Associates, PC | Falls Church | Virginia | 22042 | — |
| Sentara Norfolk | Norfolk | Virginia | 23507 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Northwest Cardiothoracic &Transplant Surgeons | Spokane | Washington | 99204 | — |
| Saint Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01166347, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 6, 2018 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01166347 live on ClinicalTrials.gov.