Efficacy Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Platinum-Refractory Head and Neck Cancers
Public ClinicalTrials.gov record NCT01166542. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Double-blind, Multicenter Two-Stage Adaptive Phase 3 Study of Intravenous Administration of REOLYSIN (Reovirus Type 3 Dearing) in Combination With Paclitaxel and Carboplatin Versus the Chemotherapy Alone in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck Who Have Progressed on or After Prior Platinum-Based Chemotherapy
Study identification
- NCT ID
- NCT01166542
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Oncolytics Biotech
- Industry
- Enrollment
- 167 participants
Conditions and interventions
Interventions
- REOLYSIN Biological
- Carboplatin Drug
- Paclitaxel Drug
- Placebo Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2010
- Primary completion
- Mar 31, 2012
- Completion
- Apr 30, 2014
- Last update posted
- Nov 4, 2014
2010 – 2014
United States locations
- U.S. sites
- 21
- U.S. states
- 16
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Arizona Oncology Associates | Tucson | Arizona | 85715 | — |
| Providence Health and Services | Burbank | California | 91505 | — |
| Wilshire Oncology Medical Group | Corona | California | 92879 | — |
| BMS Physician Practice, A Medical Corporation DBA Medical Oncology Care Associates | Orange | California | 92868 | — |
| Rocky Mountain Cancer Centers | Denver | Colorado | 80218 | — |
| Pasco Hernando Oncology Associates, PA | New Port Richey | Florida | 34652 | — |
| Emory University - Winship Cancer Institute | Altanta | Georgia | 30322 | — |
| Alexian Brothers Hospital Network | Elk Grove Village | Illinois | 60007 | — |
| Mary Bird Perkinds Cancer Center - Baton Rouge | Baton Rouge | Louisiana | 70809 | — |
| Johns Hopkins Sidney Kimmel Comprehensive Cancer Center | Baltimore | Maryland | 21231 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 59169 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Case Comprehensive Cancer Center, University Hospitals Case Medical Center | Cleveland | Ohio | 44106 | — |
| Mercy Cancer Center | Toledo | Ohio | 43623 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Texas Oncology- Sammons Cancer Center | Dallas | Texas | 75246 | — |
| Cancer Therapy and Research Center at UTHSCSA | San Antonio | Texas | 78229 | — |
| Texas Oncology - Tyler | Tyler | Texas | 75702 | — |
| Columbia Basin Hematology and Oncology | Kennewick | Washington | 99336 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 56 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01166542, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 4, 2014 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01166542 live on ClinicalTrials.gov.