Antihypertensive Treatment of Acute Cerebral Hemorrhage-II
Public ClinicalTrials.gov record NCT01176565. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH)-II: A Phase III Randomized Multicenter Clinical Trial of Blood Pressure Reduction for Hypertension in Acute Intracerebral Hemorrhage
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The specific aims of this study are to: 1. Definitively determine the therapeutic benefit of the intensive treatment relative to the standard treatment in the proportion of patients with death and disability (mRS 4-6) at 3 months among subjects with ICH who are treated within 4.5 hours of symptom onset. 2. Evaluate the therapeutic benefit of the intensive treatment relative to the standard treatment in the subjects' quality of life as measured by EuroQol at 3 months. 3. Evaluate the therapeutic benefit of the intensive treatment relative to the standard treatment in the proportion of hematoma expansion (defined as increase from baseline hematoma volume of at least 33%) and in the change from baseline peri-hematoma volume at 24 hours on the serial computed tomographic (CT) scans. 4. Assess the safety of the intensive treatment relative to the standard treatment in the proportion of subjects with treatment-related serious adverse events (SAEs) within 72 hours.
Study identification
- NCT ID
- NCT01176565
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,000 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 15, 2011 (Actual)
- Primary completion
- Dec 21, 2015 (Actual)
- Completion
- Mar 8, 2016 (Actual)
- Last update posted
- Apr 25, 2017
2011 – 2016
United States locations
- U.S. sites
- 116
- U.S. states
- 36
- U.S. cities
- 90
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAB Comprehensive Stroke Center | Birmingham | Alabama | 35249 | — |
| Maricopa Medical Center | Phoenix | Arizona | 85008 | — |
| Mayo Clinic Pheonix | Scottsdale | Arizona | 85259 | — |
| Banner University Medical Center - South Campus | Tuscon | Arizona | 85713 | — |
| Banner University Medical Center - University Campus | Tuscon | Arizona | 85724 | — |
| Community Regional Medical Center of Fresno | Fresno | California | 93721 | — |
| University of California San Diego | La Jolla | California | 92093 | — |
| Long Beach Memorial Medical Center | Long Beach | California | 90806 | — |
| Ronald Regan UCLA Medical Center | Los Angeles | California | 90095-9574 | — |
| Hoag Memorial Hospital Presbyterian | Newport Beach | California | 92658 | — |
| Stanford University | Palo Alto | California | 94304 | — |
| Sutter Roseville Medical Center | Roseville | California | 95661 | — |
| UC Davis Medical Center | Sacramento | California | 95817 | — |
| UCSF Medical Center | San Francisco | California | 94143 | — |
| Good Samaritan Hospital | San Jose | California | 95124 | — |
| Santa Clara Valley Medical Center | Santa Clara | California | 95138 | — |
| Colorado Neurological Institute | Englewood | Colorado | 80113 | — |
| Yale - New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Christiana Hospital | Newark | Delaware | 19718 | — |
| University of Florida Gainesville | Gainesville | Florida | 32611 | — |
| Baptist Medical Center Jacksonville | Jacksonville | Florida | 32207 | — |
| Mayo Clinic - Jacksonville | Jacksonville | Florida | 32224 | — |
| University of South Florida, Tampa General Hospital | Tampa | Florida | 33612 | — |
| Grady Memorial Hospital | Atlanta | Georgia | 30303 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Eastern Idaho Medical Consultants | Idaho Falls | Idaho | 83404 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Southern Illinois University Memorial Medical Center | Springfield | Illinois | 62794-9643 | — |
| Lutheran Hospital Indiana | Fort Wayne | Indiana | 46804 | — |
| Parkview Hospital | Fort Wayne | Indiana | 46805 | — |
| Kansas University Medical Center | Kansas City | Kansas | 66160 | — |
| University of Kentucky | Lexington | Kentucky | 40536-0296 | — |
| University of Louisville | Louisville | Kentucky | 40292 | — |
| West Jefferson Medical Center | Marrero | Louisiana | 70072 | — |
| Interim LSU Hospital | New Orleans | Louisiana | 70112 | — |
| Tulane Medical Center | New Orleans | Louisiana | 70112 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Louisiana State University Health Sciences Center, Shreveport | Shreveport | Louisiana | 71103 | — |
| Maine Medical Center | South Portland | Maine | 04106 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Wayne State University - Detroit Receiving Hospital | Detroit | Michigan | 48201 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Sinai-Grace Hospital | Detroit | Michigan | 48235 | — |
| Allegiance Health | Jackson | Michigan | 49201 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Essentia Health St. Mary's Medical Center | Duluth | Minnesota | 55805 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55404 | — |
| St. Cloud Hospital | Saint Cloud | Minnesota | 56303 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Saint Luke's Neuroscience Institute | Kansas City | Missouri | 64111 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| Cooper University Hospital | Camden | New Jersey | 08103 | — |
| St. Joseph's Regional Medical Center | Clifton | New Jersey | 07012 | — |
| New Jersey Neuroscience Institute, JFK Medical Center | Edison | New Jersey | 08818 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| University of New Mexico | Albuquerque | New Mexico | 87131 | — |
| New York City Health and Hospitals Corp. / Kings County Hospital | Brooklyn | New York | 11203 | — |
| Mamoides Medical Center | Brooklyn | New York | 11219 | — |
| Sister of Charity/Buffalo Mercy Hospital, Catholic Health System | Buffalo | New York | 14214 | — |
| UHS Wilson Medical Center | Johnson City | New York | 13790 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| SUNY Downstate | New York | New York | 10029 | — |
| Columbia University | New York | New York | 10032 | — |
| Lincoln Medical and Mental Health Center | New York | New York | 10451 | — |
| Rochester General Hospital | Rochester | New York | 14621 | — |
| Strong Stroke Center | Rochester | New York | 14642 | — |
| Mission Hospital | Asheville | North Carolina | 28801-4601 | — |
| Guilford Neurologic Associates | Greenboro | North Carolina | 27405 | — |
| Vidant Medical Center | Greenville | North Carolina | 27834 | — |
| Novant Clinical Research Institute/Forsyth Medical Center | Winston-Salem | North Carolina | 27103 | — |
| Wake Forest Baptist Medical Center (Wake Forest School of Medicine) | Winston-Salem | North Carolina | 27157 | — |
| Akron General Hospital | Akron | Ohio | 44307 | — |
| University Hospitals Case Medical Center | Cleveland | Ohio | 44106 | — |
| Ohio State University - Wexner Medical Center | Columbus | Ohio | 43210 | — |
| University of Toledo Medical Center | Toledo | Ohio | 43614 | — |
| Oklahoma University Health Sciences Center (OUHSC) | Oklahoma City | Oklahoma | 73104 | — |
| Providence Brain and Spine Institute | Portland | Oregon | 97225 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| Lehigh Valley Health Network | Allentown | Pennsylvania | 18103 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | — |
| Penn State Univ/ Hershey Med Center | Hershey | Pennsylvania | 17033 | — |
| Hahnemann University Hospital | Philadelphia | Pennsylvania | 19102 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Temple University | Philadelphia | Pennsylvania | 19140 | — |
| UPMC Presbyterian Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC-Mercy Hospital | Pittsburgh | Pennsylvania | 15219 | — |
| Reading Hospital | West Reading | Pennsylvania | 19611 | — |
| Wellspan York Hospital | York | Pennsylvania | 17403 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Palmetto Health | Columbia | South Carolina | 29203 | — |
| Vanderbilt Stroke Center | Nashville | Tennessee | 37232 | — |
| Seton Medical Center Austin | Austin | Texas | 78705 | — |
| St. David's Medical Center | Austin | Texas | 78705 | — |
| University Medical Center Brackenridge | Austin | Texas | 78705 | — |
| UT Southwestern - Parkland Hospital | Dallas | Texas | 75235 | — |
| Texas Tech University Health Sciences Center | El Paso | Texas | 79430 | — |
| Valley Baptist Medical Center | Harlingen | Texas | 78550 | — |
| Memorial Herman - Texas Medical Center | Houston | Texas | 77024 | — |
| Baylor College of Medicine - Ben Taub Community Hospital | Houston | Texas | 77030 | — |
| Baylor College of Medicine - St. Luke's Episcopal Hospital | Houston | Texas | 77030 | — |
| Methodist Hospital - The Neurological Institute | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| Virginia Commonwealth University Medical Center | Richmond | Virginia | 23298-0631 | — |
| West Virginia University - Ruby Memorial Hospital | Morgantown | West Virginia | 26506 | — |
| Medical College of Wisconsin | Milwakee | Wisconsin | 53226 | — |
| Aurora St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 55 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01176565, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 25, 2017 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01176565 live on ClinicalTrials.gov.