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Not listed Phase 2 Interventional

Extension Study With Tosedostat in Relapsed/Refractory Acute Myeloid Leukemia

ClinicalTrials.gov ID: NCT01180426

Public ClinicalTrials.gov record NCT01180426. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 1:22 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

The TOPAZ Study: A Long-Term Extension Study in Elderly Subjects With Relapsed/Refractory Acute Myeloid Leukemia to Allow Continued Therapy With Tosedostat

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the long-term efficacy and safety profile of tosedostat in elderly patients suffering from refractory or relapsed Acute Myeloid Leukemia.

Study identification

NCT ID
NCT01180426
Recruitment status
Not listed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Chroma Therapeutics
Industry
Enrollment
30 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
60 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2010
Primary completion
May 31, 2013
Completion
May 31, 2013
Last update posted
Feb 14, 2012

2010 – 2013

United States locations

U.S. sites
6
U.S. states
6
U.S. cities
6
Facility City State ZIP Site status
UCLA Division of Hematology/Oncology Los Angeles California 90095
University of Michigan Ann Arbor Michigan 48109-2800
John Theurer Cancer Center Hackensack New Jersey 07601
New York Presbyterian Hospitacl New York New York 10021
Duke University Medical Center Durham North Carolina 27710
MD Anderson Houston Texas 77030-4009

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01180426, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 14, 2012 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01180426 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →