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Completed Phase 2 Interventional Results available

Sofosbuvir in Combination With Pegylated Interferon and Ribavirin and in Treatment-Naive Hepatitis C-infected Patients

ClinicalTrials.gov ID: NCT01188772

Public ClinicalTrials.gov record NCT01188772. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 24, 2026, 2:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-center, Placebo-Controlled, Dose Ranging Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Following Oral Administration of PSI-7977 in Combination With Pegylated Interferon and Ribavirin in Treatment-Naïve Patients With Chronic HCV Infection Genotype 1, and an Open Label Assessment of PSI-7977 in Patients With HCV Genotypes 2 or 3

Study identification

NCT ID
NCT01188772
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Gilead Sciences
Industry
Enrollment
147 participants

Conditions and interventions

Interventions

  • Sofosbuvir Drug
  • Placebo to match sofosbuvir Drug
  • PEG Drug
  • RBV Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2010
Primary completion
Mar 31, 2011
Completion
Apr 30, 2012
Last update posted
Apr 20, 2014

2010 – 2012

United States locations

U.S. sites
22
U.S. states
14
U.S. cities
20
Facility City State ZIP Site status
Alabama Liver and Digestive Specialists Montgomery Alabama
Advanced Clinical Research Institute Anaheim California
SCTI Research Foundation Coronado California
Cedars Sinai Medical Center Los Angeles California
Dr. Jay Lalezari San Francisco California
Dr. Natalie Bzowej San Francisco California
Dr. David Nelson Gainesville Florida
Orlando Immunology Center Orlando Florida
Gastrointestinal Specialists of Georgia Marietta Georgia
University of Chicago Chicago Illinois
Dr. Mark Sulkowski Lutherville Maryland
Liver Research Center Beth Israel Deaconess Medical Center Boston Massachusetts
Kansas City Gastroenterology and Hepatology Kansas City Missouri
Dr. Bruce Bacon St Louis Missouri
North Shore University Hospital Manhasset New York
Dr. Ira Jacobson New York New York
Mount Sinai School of Medicine New York New York
Dr. Jama Darling Chapel Hill North Carolina
Dr. Raj Reddy Philadelphia Pennsylvania
Columbia Gastroenterology and Liver Associates Columbia South Carolina
Dr. Eric Lawitz San Antonio Texas
Digestive Disease Institute Virginia Mason Medical Center Seattle Washington

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01188772, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 20, 2014 · Synced Jul 24, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01188772 live on ClinicalTrials.gov.

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